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Gene · 56288

PARD3: par-3 family cell polarity regulator

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PARD3: par-3 family cell polarity regulator. Genes, record 56288. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/56288

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Gene

Symbol
PARD3
HGNC
Name
par-3 family cell polarity regulator
HGNC
NCBI Gene ID
56288
NCBI Gene
HGNC ID
HGNC:16051
HGNC
Ensembl
ENSG00000148498
NCBI Gene
Aliases
ASIP, Baz, Bazooka, PAR-3, PAR3, PAR3alpha, PARD-3, PARD3A, PPP1R118, SE2-5L16, SE2-5LT1, SE2-5T2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8TEW0Partitioning defective 3 homolog1,3561Ensembl, GeneID, HGNC

Source UniProt

Patents22

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1457069Q8TEW0Espacenet
EP 4641201 A22025-10-299775Q8TEW0Espacenet
JP 2025517969 A2025-06-129775Q8TEW0Espacenet
JP 2025032204 A2025-03-1132884Q8TEW0Espacenet
EP 4461818 A22024-11-1332884Q8TEW0Espacenet
JP 2023058610 A2023-04-2532884Q8TEW0Espacenet
JP 2022141755 A2022-09-29441Q8TEW0Espacenet
US 11446398 B22022-09-2061191Q8TEW0Espacenet
US 11400116 B22022-08-024577Q8TEW0Espacenet
JP 2022524081 A2022-04-27164162Q8TEW0Espacenet

1 to 10 of 22

See all 22 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,605

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePARD3 papersNewest fiscal year
P30CA008748Cancer Center Support Grant132025
P40OD010440Caenorhabditis Genetics Center112025
P30CA016672Cancer Center Support Grant82025
R35GM118096Regulating cell fate and shaping the body plan during morphogenesis and their alteration during oncogenesis72025
P30CA021765Cancer Center Support Grant (CCSG)52025
P40OD018537Bloomington Drosophila Stock Center at Indiana University52025
R01NS032457Cell Identity Determination in Human Brain: Somatic Mutation and Cell Lineage52025
R37AR027883Cell adhesion and tissue dynamics in the skin52025
T32HD007348Developmental Biology Training Program52025
P30CA030199Cancer Center Support Grant (CCSG)42025

1 to 10 of 1,605Source NIH's project files

See all 1,605 nih grants

Papers1,937

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Centrosome migration and apical membrane formation during epithelial polarization in MDCK cysts.Elife202642708509PubTator, text miningPubMed
An Intact PHD Finger and PHD-BRD Interdomain Linker Are Crucial for Binding of the Chromatin Remodeler Factor TIP5 to the Histone Octamer.Biomolecules202642650875PubTator, text miningPubMed
scRNA-Seq Links CD8 Effector T Cells to Periodontitis via Transcriptional Reprogramming and Enhanced PARs Signaling.Oral Dis202642638197PubTator, text miningPubMed
Endometrial Repair and Regenerative Medicine: From Broad-Spectrum Regeneration to Precision Intervention.Reprod Sci202642509440PubTator, text miningPubMed
[Identification and validation of plasma biomarkers for mild cognitive impairment based on mRNA N6-methyladenosine methylome analysis].Zhonghua Liu Xing Bing Xue Za Zhi202642373483PubTator, text miningPubMed
aPKC-ζ III promotes trophoblast fusion by altering Par-3 interactions with Hippo signaling kinase LATS1.Stem Cell Reports202642349426PubTator, text miningPubMed
PAR3-mediated coordination of hepatocyte proliferation, maturation, and architecture in liver development and regeneration.Nat Commun202642285921PubTator, text miningPubMed
Correction to "Human papillomavirus (HPV)-18 E6 oncoprotein interferes with the epithelial cell polarity Par3 protein".Mol Oncol202642231790PubTator, text miningPubMed
Corrigendum to: "Pard3 promotes corneal epithelial stratification and homeostasis by regulating apical-basal polarity, cytoskeletal organization and tight junction-mediated barrier function" [Ocul Surf 37 (2025) 201-215, https://doi.org/10.1016/j.jtos.2025.04.001].
Ocul Surf202642092634PubTator, text miningPubMed
Inflammation Does Not Mediate Relationships between BMI/BMI-for-Age Z-Score and Retinol or Retinol-Binding Protein in Adult Women or Young Children without Underweight, Wasting, or Malaria: An Analysis of 24 Surveys.
Curr Dev Nutr202642077216PubTator, text miningPubMed

1 to 10 of 1,937

See all 1,937 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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