Gene · 5629
PROX1: prospero homeobox 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PROX1: prospero homeobox 1. Genes, record 5629. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5629
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q92786 | Prospero homeobox protein 1 | 737 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents73
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 59387 | Q92786 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 59389 | Q92786 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 59391 | Q92786 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 1483 | Q92786 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 8296 | Q92786 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15539 | Q92786 | Espacenet |
| JP 2025121934 A | 2025-08-20 | 2 | Q92786 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 1483 | Q92786 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 8296 | Q92786 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 34101 | Q92786 | Espacenet |
1 to 10 of 73
See all 73 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,651
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PROX1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA021765 | Cancer Center Support Grant (CCSG) | 17 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 14 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 13 | 2025 |
| R01DK062370 | Identifying Genes for Type 2 Diabetes: FUSION | 9 | 2025 |
| R01DK093757 | Genetic epidemiology of rare and regulatory variants for metabolic traits | 9 | 2025 |
| R01EY012200 | Pax6 as a key regulator of lens development | 9 | 2025 |
| R01HL133216 | Molecular Mechanisms Controlling Lymphatic Vascular Function in Health and Disease | 8 | 2025 |
| ZIAHG000024 | Genetic analysis of type II diabetes | 8 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 7 | 2025 |
| P30DK020572 | Michigan Diabetes Research Center (MDRC) | 7 | 2025 |
1 to 10 of 2,651Source NIH's project files
See all 2,651 nih grantsPapers3,195
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| PROX1-associated lymphatic reprogramming signatures in pediatric adamantinomatous craniopharyngioma: a comparative study with adult cases. | Front Pediatr | 2026 | 42819307 | PubTator, text mining | PubMed |
| Genetically engineered porcine liver: a new era in transplantation. | Int J Surg | 2026 | 42808109 | PubTator, text mining | PubMed |
| Molecular Distinctions, Diagnosis, and Mechanism-Based Therapies in Lipedema and Obesity. | Curr Issues Mol Biol | 2026 | 42793248 | PubTator, text mining | PubMed |
| Ferroptosis, immune activation and MASH-related HCC. | Gut | 2026 | 42722415 | PubTator, text mining | PubMed |
| Engineering lymphatic collecting vessel phenotypes through combined hyaluronic acid cues and oscillatory shear stress. | Cell Rep Methods | 2026 | 42697195 | PubTator, text mining | PubMed |
| Prox1: A Novel Barrier to Retinal Regeneration and a Potential Target for Vision Restoration. | WMJ | 2026 | 42623612 | PubTator, text mining | PubMed |
| Restoration of oscillatory shear stress in humans activates an endothelial protective genetic program and prevents DVT. | Blood | 2026 | 42611796 | PubTator, text mining | PubMed |
| Impaired lymphatic drainage in a child with hydrops fetalis and a novel variant in the PROX1 gene: case report and review of literature. | Front Cardiovasc Med | 2026 | 42591134 | PubTator, text mining | PubMed |
| Endothelial VEGFR2 insufficiency promotes the transition of lymphatic to hematopoietic transcriptional programs. | Angiogenesis | 2026 | 42503070 | PubTator, text mining | PubMed |
| The Scaffold Protein Liprin β-1 (PPFIBP1) and the Intermediate Filament Synemin: Potential New Markers of Lymphatic Endothelial Cells. | Cells | 2026 | 42346091 | PubTator, text mining | PubMed |
1 to 10 of 3,195
See all 3,195 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5629
GET https://conductscience.org/api/genes/v1/5629/patents?page=2