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Gene · 5630

PRPH: peripherin

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PRPH: peripherin. Genes, record 5630. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5630

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Gene

Symbol
PRPH
HGNC
Name
peripherin
HGNC
NCBI Gene ID
5630
NCBI Gene
HGNC ID
HGNC:9461
HGNC
Ensembl
ENSG00000135406
NCBI Gene
Aliases
NEF4, PRPH1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P41219Peripherin4700Ensembl, GeneID, HGNC

Source UniProt

Patents75

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4821560 A22026-10-1420P41219Espacenet
JP 2026004568 A2026-01-1457374P41219Espacenet
EP 4670794 A22025-12-314P41219Espacenet
JP 2025539844 A2025-12-0958P41219Espacenet
WO 2025199149 A12025-09-256017P41219Espacenet
KR 1020250115413 A2025-07-3058P41219Espacenet
US 12310997 B22025-05-2714P41219Espacenet
JP 2025039615 A2025-03-2120P41219Espacenet
US 12246046 B22025-03-1139P41219Espacenet
KR 1020250023600 A2025-02-1814P41219Espacenet

1 to 10 of 75

See all 75 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,173

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePRPH papersNewest fiscal year
R01EY010609Mechanism of photoreceptor cell degeneration in animal models of retinal diseases112025
R01NS114567Precision Medicine for the Peripheral Nervous System Disorder Familiar Dysautonomia62025
P30EY001583P30 Core Grant For Vision Research52025
P30EY001792P30 Core Grant for Vision Research52025
P30EY005722Center Core Grant for Vision Research52025
R01DE017914Molecular Interactions during Neural Crest Formation52025
R01EY006855Models for Therapy of Hereditary Retinal Degeneration52025
U19NS130608Human Nociceptor and Spinal Cord Molecular Signature Center52025
P30EY000331Vision Research Core at UCLA42025
P30EY014800University of Utah Core Vision Research Grant42025

1 to 10 of 1,173Source NIH's project files

See all 1,173 nih grants

Papers1,636

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Establishment of a human pluripotent stem cell-derived sensory neuron platform for studying diabetes-associated metabolic and oxidative stress-induced neuronal injury.J Neurosci Methods202742826868PubTator, text miningPubMed
Bioactive keratin-pectin methacrylate multifilament nerve conduits for functional regeneration across segmental nerve defects.Int J Biol Macromol202642748994PubTator, text miningPubMed
Article commentary on: 'Serum peripherin as a disease biomarker in hereditary transthyretin amyloidosis: a multicenter cohort study'.Amyloid202642683509PubTator, text miningPubMed
Opioid Exposure Induces the Expression of the Purinergic Receptor P2RY11 in Human Nociceptors.Cells202642645192PubTator, text miningPubMed
Modeling sympathetic neuro-cardiac interactions in a hiPSC-based microphysiological system.Lab Chip202642635618PubTator, text miningPubMed
Unmyelinated nerve fibers distributed in the human crural fascia of Thiel-embalmed cadavers.Sci Rep202642365064PubTator, text miningPubMed
Optimizing NGN2 Dosage Enhances the Neuronal Enrichment of iPSC-Derived Neuronal Cultures.Mol Cell Proteomics202642309337PubTator, text miningPubMed
Evaluation of serum neurofilament light chain, GFAP, and peripherin as biomarkers in hereditary transthyretin amyloidosis.Sci Rep202642259879PubTator, text miningPubMed
From Axonal Growth to Neurodegeneration: The Dual Role of Neurofilament Dynamics in Health and Disease.NeuroSci202642200920PubTator, text miningPubMed
Cytosolic heat shock protein 90 is required for photoreceptor outer segment development and vision.J Biol Chem202642184858PubTator, text miningPubMed

1 to 10 of 1,636

See all 1,636 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5630

GET https://conductscience.org/api/genes/v1/5630/patents?page=2