Gene · 5648
MASP1: MBL associated serine protease 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. MASP1: MBL associated serine protease 1. Genes, record 5648. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5648
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P48740 | Mannan-binding lectin serine protease 1 | 699 | 9 | Ensembl, GeneID, HGNC |
Source UniProt
Patents74
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 52507 | P48740 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 6224 | P48740 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 8323 | P48740 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6978 | P48740 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6978 | P48740 | Espacenet |
| WO 2025132452 A1 | 2025-06-26 | 11 | P48740 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 6224 | P48740 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 31233 | P48740 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 8323 | P48740 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 8323 | P48740 | Espacenet |
1 to 10 of 74
See all 74 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants897
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MASP1 papers | Newest fiscal year |
|---|---|---|---|
| R01AR051749 | Complement in the Pathogenesis of Autoimmune Arthritis | 14 | 2025 |
| R01DK078244 | Molecular Basis of Pathogenicity of IgA1-containing Immune Complexes | 6 | 2025 |
| ZIACP010121 | Molecular Epidemiology Studies of Occupational and Environmental Exposures | 4 | 2025 |
| I01RX000444 | Complement Factor H-based Therapeutic Strategies in Macular Degeneration | 3 | 2025 |
| R01DK076690 | Complement-mediated injury of the kidney: New mechanisms and novel therapies | 3 | 2025 |
| R01DK110023 | C3 Glomerulopathy -- A Collaborative Study | 3 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 2 | 2025 |
| P30CA034196 | Cancer Center Support (CORE) Grant | 2 | 2025 |
| P30CA086862 | Cancer Center Support Grant | 2 | 2025 |
| P30CA134274 | UNIVERSITY OF MARYLAND GREENEBAUM CANCER CENTERSUPPORT GRANT | 2 | 2025 |
1 to 10 of 897Source NIH's project files
See all 897 nih grantsPapers2,041
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Complement expression profiles in human glomerular mesangial cells, endothelial cells, podocytes and proximal tubular epithelial cells. | Front Immunol | 2026 | 42746023 | PubTator, text mining | PubMed |
| Traumatic Brain Injury in the Omics Era: Plasma and Extracellular Vesicle Proteomic Signatures in Polytrauma. | Med Sci (Basel) | 2026 | 42646564 | PubTator, text mining | PubMed |
| Point-of-care assessment of complement activation in the ICU: a feasibility study of rapid terminal complement complex detection in critical illness. | Front Immunol | 2026 | 42643423 | PubTator, text mining | PubMed |
| Sex-Associated Proteomic Signatures Persist Independent of Injury Severity and Shock Physiology in Acute Trauma. | Shock | 2026 | 42625553 | PubTator, text mining | PubMed |
| Diverging Liquid-Liquid Phase Separation Behavior of Different Recombinant Major Ampullate Spidroins. | Adv Sci (Weinh) | 2026 | 42621696 | PubTator, text mining | PubMed |
| Coordinated suppression of lectin complement pathway effectors and upregulation of SERPING1 defines a thrombo-inflammatory regulatory signature in Acute Coronary disease. | Mol Biol Rep | 2026 | 42606632 | PubTator, text mining | PubMed |
| Serum complement system activation in normal healing and atrophic non-union of human long bone fractures. | Front Immunol | 2026 | 42344890 | PubTator, text mining | PubMed |
| Screening and identification of key genes related to the immune microenvironment of rectal cancer influenced by radiotherapy based on bioinformatics methods. | Discov Oncol | 2026 | 42298234 | PubTator, text mining | PubMed |
| Prenatal Phenotype of Common Arterial Trunk With Tricuspid Atresia and Bilateral Cleft Lip-Palate With Novel MASP1 Variant. | Prenat Diagn | 2026 | 42185514 | PubTator, text mining | PubMed |
| Correlation of serum MAp44 protein concentration with degree of myocardial injury and 30-day prognosis in patients with acute myocardial infarction. | Am J Transl Res | 2026 | 42170458 | PubTator, text mining | PubMed |
1 to 10 of 2,041
See all 2,041 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5648
GET https://conductscience.org/api/genes/v1/5648/patents?page=2