Gene · 5649
RELN: reelin
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. RELN: reelin. Genes, record 5649. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5649
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P78509 | Reelin | 3,460 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents40
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 12516 | P78509 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 13759 | P78509 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 11314 | P78509 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7547 | P78509 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 7547 | P78509 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 13759 | P78509 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 12516 | P78509 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 34717 | P78509 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 11314 | P78509 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 11314 | P78509 | Espacenet |
1 to 10 of 40
See all 40 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants3,176
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | RELN papers | Newest fiscal year |
|---|---|---|---|
| P30CA021765 | Cancer Center Support Grant (CCSG) | 14 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 11 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 11 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 8 | 2025 |
| U24AG021886 | National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD) | 8 | 2025 |
| R01NS058721 | ACC: Callosal Agenesis as a Window into Common Neurodevelopmental Disorders | 7 | 2025 |
| R01NS081297 | The Development and Integration of Early Born SST-Expressing Interneurons in the Cortex | 5 | 2025 |
| R24HD000836 | Laboratory of Developmental Biology | 5 | 2025 |
| R35GM128915 | Molecular Principles Governing Mitochondrial and Peroxisomal Remodeling as Drivers of Cell Fate and Identity | 5 | 2025 |
| R37NS035129 | Human Epilepsy Genetics - Mosaic Mutations in Focal Epilepsy | 5 | 2025 |
1 to 10 of 3,176Source NIH's project files
See all 3,176 nih grantsPapers3,990
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Zygosity-Dependent Phenotypic Spectrum of RELN-Related Disorders: 10 New Patients and Genotype-Phenotype Correlations Across 48 Kindreds. | Hum Mutat | 2026 | 42761500 | PubTator, text mining | PubMed |
| Integrative analysis of single-cell multi-omics reveals heterogeneity in piriform cortex principal neurons and their selective vulnerability in Alzheimer's disease. | Clin Transl Med | 2026 | 42728785 | PubTator, text mining | PubMed |
| Lymphatics-epicardial cross talk via Reelin controls cardiac growth. | Genes Dev | 2026 | 42728022 | PubTator, text mining | PubMed |
| The neuronal network of small cell lung cancer: a narrative review of the role of the nervous system in the pathogenesis and progression. | Transl Lung Cancer Res | 2026 | 42723782 | PubTator, text mining | PubMed |
| High reelin expression may explain why a subgroup of entorhinal cortex neurons functions as an initial nucleation site of Alzheimer's disease. | PLoS Comput Biol | 2026 | 42640981 | PubTator, text mining | PubMed |
| Functional Reelin signaling deficits without interneuron loss are associated with neuroblast misplacement after non-convulsive status epilepticus. | Neurobiol Dis | 2026 | 42637105 | PubTator, text mining | PubMed |
| Alzheimer's Disease DNA Methylation Index (AD-DMI) and its Association with Late-Life Cognitive Function. | NPJ Dement | 2026 | 42583477 | PubTator, text mining | PubMed |
| Molecular links between reelin downregulation, topoisomerase IIβ alterations, and proteins involved in Alzheimer pathology in human SH-SY5Y neuroblastoma cell line. | Exp Brain Res | 2026 | 42377581 | PubTator, text mining | PubMed |
| Broader autism phenotype, the default mode network, and brain entropy: A network-level hypothesis. | Res Neurodivers | 2026 | 42369596 | PubTator, text mining | PubMed |
| The association study of genetic variants with developing musical aptitude in humans. | Vavilovskii Zhurnal Genet Selektsii | 2026 | 42245177 | PubTator, text mining | PubMed |
1 to 10 of 3,990
See all 3,990 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5649
GET https://conductscience.org/api/genes/v1/5649/patents?page=2