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PRTN3: proteinase 3

1 protein, 124 patents, 0 drugs, 0 trials, 2,607 NIH grants and 13,610 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPRTN3HGNC
Nameproteinase 3HGNC
NCBI Gene ID5657NCBI Gene
HGNC IDHGNC:9495HGNC
EnsemblENSG00000196415NCBI Gene
AliasesACPA, AGP7, C-ANCA, CANCA, MBN, MBT, NP-4, NP4, P29, PR-3, PR3NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P24158Myeloblastin2562Ensembl, GeneID, HGNCUniProt

Patents 124

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026513892 A2026-05-014P24158Espacenet
EP 4689095 A22026-02-114P24158Espacenet
JP 2026501772 A2026-01-161P24158Espacenet
JP 2026004568 A2026-01-1460205P24158Espacenet
JP 2026000906 A2026-01-06120P24158Espacenet
JP 2025541179 A2025-12-1825P24158Espacenet
KR 1020250174635 A2025-12-124P24158Espacenet
EP 4650780 A22025-11-19885P24158Espacenet
EP 4630459 A12025-10-1525P24158Espacenet
JP 2025147176 A2025-10-0610963P24158Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2607

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant332,025NIH's project files
ZIAAR041199Systemic Autoimmunity252,025NIH's project files
P30AR070253Joint Biology Consortium Resource-based Center212,025NIH's project files
T32AR007534Research Training in Rheumatology192,025NIH's project files
T32AR050942Training Program in Adult and Pediatric Rheumatology172,025NIH's project files
ZIAAR041204Vasculitis and Translational Medicine152,025NIH's project files
R01AI015614Pathogenesis of Fever in Man142,025NIH's project files
U54GM115458Great Plains IDeA-CTR142,025NIH's project files
P30AR072577VERITY: Value and Evidence in Rheumatology using bioInformaTics, and advanced analYtics122,025NIH's project files
R01AR063759Defining the influence of RA genetic susceptibility factors on T cell antigen specificity and functional state122,025NIH's project files

Papers 13610

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42816391PubTator, text miningPubMed
42801333PubTator, text miningPubMed
42796760PubTator, text miningPubMed
42796306PubTator, text miningPubMed
42789389PubTator, text miningPubMed
42786675PubTator, text miningPubMed
42783221PubTator, text miningPubMed
42767097PubTator, text miningPubMed
42761370PubTator, text miningPubMed
42733890PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license