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Gene · 5660

PSAP: prosaposin

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PSAP: prosaposin. Genes, record 5660. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5660

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Gene

Symbol
PSAP
HGNC
Name
prosaposin
HGNC
NCBI Gene ID
5660
NCBI Gene
HGNC ID
HGNC:9498
HGNC
Ensembl
ENSG00000197746
NCBI Gene
Aliases
GLBA, PARK24, PSAPD, SAP1, SAP2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P07602Prosaposin52421Ensembl, GeneID, HGNC

Source UniProt

Patents150

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026210020 A12026-10-08140P07602Espacenet
JP 2026071207 A2026-04-281750P07602Espacenet
JP 2026067851 A2026-04-21298P07602Espacenet
US 12570963 B22026-03-1016P07602Espacenet
WO 2026048718 A2026-03-0515P07602Espacenet
JP 2026004568 A2026-01-1459384P07602Espacenet
US 12516298 B22026-01-0616P07602Espacenet
EP 4650780 A22025-11-1911213P07602Espacenet
EP 4641201 A22025-10-2911676P07602Espacenet
JP 2025160208 A2025-10-2210P07602Espacenet

1 to 10 of 150

See all 150 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,304

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePSAP papersNewest fiscal year
P01AG019724Frontotemporal Dementia: Genes, Images, and Emotions102025
R01NS088448Function of TMEM106B in Neurodegeneration92025
R01NS095954Lysosomal Function of Progranulin and Neurodegeneration82025
UL1TR001863Yale Clinical and Translational Science Award72025
P30CA008748Cancer Center Support Grant62025
ZIAHG200336Genetic and clinical studies of Gaucher disease and other lysosomal disorders62025
P30CA006973Regional Oncology Research Center52025
U19AG063911ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2)52025
U24AG021886National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)52025
P30CA062203Cancer Center Support Grant42025

1 to 10 of 1,304Source NIH's project files

See all 1,304 nih grants

Papers2,070

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
AZP2006 in Parkinson's disease models: A promising new neuroprotective treatment involving lysosomal homeostasis and the Progranulin/Prosaposin complex.PLoS One202642814712PubTator, text miningPubMed
A guide to selecting high-performing antibodies for Prosaposin (UniProt ID: P07602) for use in western blot and immunoprecipitation.F1000Res202642802730PubTator, text miningPubMed
Leukodystrophy in Tanzania: A Case Study Highlighting Diagnostic Dilemmas and Clinical Implications.Clin Case Rep202642787314PubTator, text miningPubMed
Large-scale genomic analysis places Chinese CC398 as a persistent human-associated MSSA lineage apart from the dominant global LA-MRSA clade.mSystems202642725741PubTator, text miningPubMed
Plasma proteomic profiling of septic shock and acute pancreatitis identifies shared signatures and disease-specific pathways.Sci Rep202642702635PubTator, text miningPubMed
Systematic characterizations of a urinary protein, prosaposin, as a novel inhibitor of calcium oxalate stone formation.Int J Biol Macromol202642632498PubTator, text miningPubMed
Integrating machine learning and multi-omics analysis to identify and validate key genes associated with periodontitis.Acta Odontol Scand202642615493PubTator, text miningPubMed
Translating single-cell RNA sequencing into monocyte direct leukocyte subpopulation-transcript abundance assay ratio-based biomarkers (IFI27/PSAP or IFI27/CTSS) for clinical detection of viral infection.
Pathology202642595652PubTator, text miningPubMed
Integrative analysis reveals multitarget associations of liquid crystal monomer in ovulatory dysfunction: insights from composite and subtype-specific Mendelian randomization.F S Sci202642586262PubTator, text miningPubMed
APOE Genotypes Modulate the Relationship of Hypertension With Alzheimer's Disease: Associations and Clues of Peripheral Mechanisms.Biol Psychiatry Glob Open Sci202642569203PubTator, text miningPubMed

1 to 10 of 2,070

See all 2,070 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5660

GET https://conductscience.org/api/genes/v1/5660/patents?page=2