Gene · 5660
PSAP: prosaposin
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PSAP: prosaposin. Genes, record 5660. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5660
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P07602 | Prosaposin | 524 | 21 | Ensembl, GeneID, HGNC |
Source UniProt
Patents150
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| WO 2026210020 A1 | 2026-10-08 | 140 | P07602 | Espacenet |
| JP 2026071207 A | 2026-04-28 | 1750 | P07602 | Espacenet |
| JP 2026067851 A | 2026-04-21 | 298 | P07602 | Espacenet |
| US 12570963 B2 | 2026-03-10 | 16 | P07602 | Espacenet |
| WO 2026048718 A | 2026-03-05 | 15 | P07602 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 59384 | P07602 | Espacenet |
| US 12516298 B2 | 2026-01-06 | 16 | P07602 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 11213 | P07602 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 11676 | P07602 | Espacenet |
| JP 2025160208 A | 2025-10-22 | 10 | P07602 | Espacenet |
1 to 10 of 150
See all 150 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,304
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PSAP papers | Newest fiscal year |
|---|---|---|---|
| P01AG019724 | Frontotemporal Dementia: Genes, Images, and Emotions | 10 | 2025 |
| R01NS088448 | Function of TMEM106B in Neurodegeneration | 9 | 2025 |
| R01NS095954 | Lysosomal Function of Progranulin and Neurodegeneration | 8 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 7 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| ZIAHG200336 | Genetic and clinical studies of Gaucher disease and other lysosomal disorders | 6 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 5 | 2025 |
| U19AG063911 | ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2) | 5 | 2025 |
| U24AG021886 | National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD) | 5 | 2025 |
| P30CA062203 | Cancer Center Support Grant | 4 | 2025 |
1 to 10 of 1,304Source NIH's project files
See all 1,304 nih grantsPapers2,070
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| AZP2006 in Parkinson's disease models: A promising new neuroprotective treatment involving lysosomal homeostasis and the Progranulin/Prosaposin complex. | PLoS One | 2026 | 42814712 | PubTator, text mining | PubMed |
| A guide to selecting high-performing antibodies for Prosaposin (UniProt ID: P07602) for use in western blot and immunoprecipitation. | F1000Res | 2026 | 42802730 | PubTator, text mining | PubMed |
| Leukodystrophy in Tanzania: A Case Study Highlighting Diagnostic Dilemmas and Clinical Implications. | Clin Case Rep | 2026 | 42787314 | PubTator, text mining | PubMed |
| Large-scale genomic analysis places Chinese CC398 as a persistent human-associated MSSA lineage apart from the dominant global LA-MRSA clade. | mSystems | 2026 | 42725741 | PubTator, text mining | PubMed |
| Plasma proteomic profiling of septic shock and acute pancreatitis identifies shared signatures and disease-specific pathways. | Sci Rep | 2026 | 42702635 | PubTator, text mining | PubMed |
| Systematic characterizations of a urinary protein, prosaposin, as a novel inhibitor of calcium oxalate stone formation. | Int J Biol Macromol | 2026 | 42632498 | PubTator, text mining | PubMed |
| Integrating machine learning and multi-omics analysis to identify and validate key genes associated with periodontitis. | Acta Odontol Scand | 2026 | 42615493 | PubTator, text mining | PubMed |
Translating single-cell RNA sequencing into monocyte direct leukocyte subpopulation-transcript abundance assay ratio-based biomarkers (IFI27/PSAP or IFI27/CTSS) for clinical detection of viral infection. | Pathology | 2026 | 42595652 | PubTator, text mining | PubMed |
| Integrative analysis reveals multitarget associations of liquid crystal monomer in ovulatory dysfunction: insights from composite and subtype-specific Mendelian randomization. | F S Sci | 2026 | 42586262 | PubTator, text mining | PubMed |
| APOE Genotypes Modulate the Relationship of Hypertension With Alzheimer's Disease: Associations and Clues of Peripheral Mechanisms. | Biol Psychiatry Glob Open Sci | 2026 | 42569203 | PubTator, text mining | PubMed |
1 to 10 of 2,070
See all 2,070 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5660
GET https://conductscience.org/api/genes/v1/5660/patents?page=2