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Gene · 5670

PSG2: pregnancy specific beta-1-glycoprotein 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PSG2: pregnancy specific beta-1-glycoprotein 2. Genes, record 5670. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5670

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Gene

Symbol
PSG2
HGNC
Name
pregnancy specific beta-1-glycoprotein 2
HGNC
NCBI Gene ID
5670
NCBI Gene
HGNC ID
HGNC:9519
HGNC
Ensembl
ENSG00000242221
NCBI Gene
Aliases
CEA, PSBG2, PSG1, PSGGB
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P11465Pregnancy-specific beta-1-glycoprotein 23350Ensembl, GeneID, HGNC

Source UniProt

Patents29

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1458952P11465Espacenet
JP 2026004568 A2026-01-1458953P11465Espacenet
JP 2026004568 A2026-01-1458954P11465Espacenet
EP 4641201 A22025-10-2912802P11465Espacenet
JP 2025147176 A2025-10-0610983P11465Espacenet
JP 2025529142 A2025-09-047476P11465Espacenet
US 12371689 B22025-07-297476P11465Espacenet
JP 2025517969 A2025-06-1212802P11465Espacenet
JP 2025028160 A2025-02-2810983P11465Espacenet
KR 1020250010750 A2025-01-2110983P11465Espacenet

1 to 10 of 29

See all 29 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants956

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePSG2 papersNewest fiscal year
P30CA008748Cancer Center Support Grant262025
P30CA016672Cancer Center Support Grant162025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant52025
P30CA047904Cancer Center Support Grant52025
P30CA014520UW Comprehensive Cancer Center Support42025
ZIABC010944Strategies for Cancer Immunotherapy Development: Preclinical Studies42025
P30CA006973Regional Oncology Research Center32025
ZIABC010598Human Immune Responses to Tumor Antigens for Cancer Immunotherapy32025
P30CA006927Comprehensive Cancer Center Program at Fox Chase22025
P30CA010815Consolidated Basic Cancer Research Program22025

1 to 10 of 956Source NIH's project files

See all 956 nih grants

Papers3,544

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Kushenol E Attenuates AOM/DSS-induced Colorectal Tumorigenesis in Mice, Inhibits Proliferation, and Induces Apoptosis in HT-29 Colorectal Cancer Cells.Recent Pat Anticancer Drug Discov202642770354PubTator, text miningPubMed
Diagnosis of ovarian cancer using multiple biomarkers of CA 125, CA153, CA 19-9, CEA, HE4 and ROMA index.Ann Biol Clin (Paris)202642698297PubTator, text miningPubMed
Unique amino acid substitution within the spike glycoprotein S1 subunit promotes infectious bronchitis virus infection via enhancing viral attachment.mBio202642690048PubTator, text miningPubMed
Survival Outcomes of Patients With Colorectal Cancer After Primary Surgery: A Population-Based Study in Hainan, China.Cancer Med202642613306PubTator, text miningPubMed
PSG2 Impairs Human Trophoblast Function in Preeclampsia by Activating TGF-β/Smad3 to Suppress EMT and MMP2/9 Expression.Biol Reprod202642573986PubTator, text miningPubMed
Efficacy of Pazopanib for a Patient with FGFR1-Amplified Breast Cancer: A Case Report.Case Rep Oncol202642524362PubTator, text miningPubMed
Malignant transformation of mature ovarian teratoma into goblet cell adenocarcinoma: a case report.Gynecol Oncol Rep202642518873PubTator, text miningPubMed
A nomogram prediction model for brain metastases in patients with lung adenocarcinoma.Oncol Lett202642491225PubTator, text miningPubMed
Laparoscopic extended cholecystectomy with extended left hemi-hepatectomy (left lobe & S5), after interventional therapy and neoadjuvant chemotherapy for stage IIIb GBC.Surg Oncol202642485805PubTator, text miningPubMed
Inverse co-variation of circulating PIWIL2 and PIWIL4 in gastric adenocarcinoma: an exploratory ELISA-based study.Clin Proteomics202642402549PubTator, text miningPubMed

1 to 10 of 3,544

See all 3,544 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5670

GET https://conductscience.org/api/genes/v1/5670/patents?page=2