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Gene · 56829

ZC3HAV1: zinc finger CCCH-type containing, antiviral 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ZC3HAV1: zinc finger CCCH-type containing, antiviral 1. Genes, record 56829. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/56829

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Gene

Symbol
ZC3HAV1
HGNC
Name
zinc finger CCCH-type containing, antiviral 1
HGNC
NCBI Gene ID
56829
NCBI Gene
HGNC ID
HGNC:23721
HGNC
Ensembl
ENSG00000105939
NCBI Gene
Aliases
ARTD13, FLB6421, FLJ13288, MGC48898, PARP13, ZAP, ZC3H2, ZC3HDC2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q7Z2W4Zinc finger CCCH-type antiviral protein 19027Ensembl, GeneID, HGNC

Source UniProt

Patents20

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1470219Q7Z2W4Espacenet
EP 4650780 A22025-11-191060Q7Z2W4Espacenet
JP 2025517970 A2025-06-121060Q7Z2W4Espacenet
US 11884978 B22024-01-30813Q7Z2W4Espacenet
US 11873486 B22024-01-1617Q7Z2W4Espacenet
US 11446398 B22022-09-2098894Q7Z2W4Espacenet
JP 2022524081 A2022-04-27201865Q7Z2W4Espacenet
US 11293927 B22022-04-0523Q7Z2W4Espacenet
US 11078247 B22021-08-0312770Q7Z2W4Espacenet
WO 2020043864 A12020-03-052864Q7Z2W4Espacenet

1 to 10 of 20

See all 20 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,110

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleZC3HAV1 papersNewest fiscal year
P30CA014051Cancer Center Support (Core) Grant92025
P20GM113117Chemical Biology of Infectious Disease82025
P30CA016672Cancer Center Support Grant82025
P30CA008748Cancer Center Support Grant72025
P30CA015704Cancer Center Support Grant42025
P30CA021765Cancer Center Support Grant (CCSG)42025
P30CA069533OHSU Knight Cancer Institute42025
R01AI129269Olfactory and neurological manifestations of acute and post-acute murine COVID-1942025
R01AI158704Functional analysis of host and viral determinants for ZAP inhibition42025
R01DK069710The Role of Nuclear PARPs in Signal-Regulated Transcription42025

1 to 10 of 1,110Source NIH's project files

See all 1,110 nih grants

Papers1,573

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Interferon-stimulated restriction factors in enterovirus infection: A review on the mechanisms and antiviral roles of shiftless (C19orf66).Virology202742784970PubTator, text miningPubMed
A feline coronavirus nucleocapsid protein disrupts ZC3HAV1-viral RNA association to counteract host RNA-level restriction.PLoS Pathog202642758786PubTator, text miningPubMed
BRAF fusions define therapeutic vulnerability and tyrosine kinase inhibitor resistance in non-small cell lung cancer.Lung Cancer202642546514PubTator, text miningPubMed
An integrative epigenomic and single-cell framework identifies a prognostic DNA methylation risk score and ZNF638 silencing in urothelial carcinoma.J Transl Med202642443907PubTator, text miningPubMed
Comprehensive investigation of hypoxia-associated genes and their predictive significance in osteosarcoma.Transl Oncol202642322695PubTator, text miningPubMed
Correction to "Lycorine Derivative Inhibits SARS-CoV-2 Replication by Reducing -1 Programmed Ribosomal Frameshifting via Targeting ZAP".MedComm (2020)202642253944PubTator, text miningPubMed
Lost in translation: interferon-stimulated genes targeting flavivirus protein synthesis.J Virol202642240343PubTator, text miningPubMed
SPRY domains encode ubiquitin ligase specificity for ZAP and RIG-I.PLoS Pathog202642102160PubTator, text miningPubMed
Evolutionary Conservation, Expansion and Diversification of Interferon stimulated genes (ISG) in Vertebrates: insights from fish.Biomed J202642055280PubTator, text miningPubMed
The long isoform of ZAP coordinates multiple enzymes to mediate complete decay of target transcripts.Cell Rep202642054207PubTator, text miningPubMed

1 to 10 of 1,573

See all 1,573 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/56829

GET https://conductscience.org/api/genes/v1/56829/patents