Gene · 56829
ZC3HAV1: zinc finger CCCH-type containing, antiviral 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ZC3HAV1: zinc finger CCCH-type containing, antiviral 1. Genes, record 56829. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/56829
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q7Z2W4 | Zinc finger CCCH-type antiviral protein 1 | 902 | 7 | Ensembl, GeneID, HGNC |
Source UniProt
Patents20
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 70219 | Q7Z2W4 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 1060 | Q7Z2W4 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 1060 | Q7Z2W4 | Espacenet |
| US 11884978 B2 | 2024-01-30 | 813 | Q7Z2W4 | Espacenet |
| US 11873486 B2 | 2024-01-16 | 17 | Q7Z2W4 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 98894 | Q7Z2W4 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 201865 | Q7Z2W4 | Espacenet |
| US 11293927 B2 | 2022-04-05 | 23 | Q7Z2W4 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 12770 | Q7Z2W4 | Espacenet |
| WO 2020043864 A1 | 2020-03-05 | 2864 | Q7Z2W4 | Espacenet |
1 to 10 of 20
See all 20 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,110
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ZC3HAV1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA014051 | Cancer Center Support (Core) Grant | 9 | 2025 |
| P20GM113117 | Chemical Biology of Infectious Disease | 8 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 8 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 4 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 4 | 2025 |
| P30CA069533 | OHSU Knight Cancer Institute | 4 | 2025 |
| R01AI129269 | Olfactory and neurological manifestations of acute and post-acute murine COVID-19 | 4 | 2025 |
| R01AI158704 | Functional analysis of host and viral determinants for ZAP inhibition | 4 | 2025 |
| R01DK069710 | The Role of Nuclear PARPs in Signal-Regulated Transcription | 4 | 2025 |
1 to 10 of 1,110Source NIH's project files
See all 1,110 nih grantsPapers1,573
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Interferon-stimulated restriction factors in enterovirus infection: A review on the mechanisms and antiviral roles of shiftless (C19orf66). | Virology | 2027 | 42784970 | PubTator, text mining | PubMed |
| A feline coronavirus nucleocapsid protein disrupts ZC3HAV1-viral RNA association to counteract host RNA-level restriction. | PLoS Pathog | 2026 | 42758786 | PubTator, text mining | PubMed |
| BRAF fusions define therapeutic vulnerability and tyrosine kinase inhibitor resistance in non-small cell lung cancer. | Lung Cancer | 2026 | 42546514 | PubTator, text mining | PubMed |
| An integrative epigenomic and single-cell framework identifies a prognostic DNA methylation risk score and ZNF638 silencing in urothelial carcinoma. | J Transl Med | 2026 | 42443907 | PubTator, text mining | PubMed |
| Comprehensive investigation of hypoxia-associated genes and their predictive significance in osteosarcoma. | Transl Oncol | 2026 | 42322695 | PubTator, text mining | PubMed |
| Correction to "Lycorine Derivative Inhibits SARS-CoV-2 Replication by Reducing -1 Programmed Ribosomal Frameshifting via Targeting ZAP". | MedComm (2020) | 2026 | 42253944 | PubTator, text mining | PubMed |
| Lost in translation: interferon-stimulated genes targeting flavivirus protein synthesis. | J Virol | 2026 | 42240343 | PubTator, text mining | PubMed |
| SPRY domains encode ubiquitin ligase specificity for ZAP and RIG-I. | PLoS Pathog | 2026 | 42102160 | PubTator, text mining | PubMed |
| Evolutionary Conservation, Expansion and Diversification of Interferon stimulated genes (ISG) in Vertebrates: insights from fish. | Biomed J | 2026 | 42055280 | PubTator, text mining | PubMed |
| The long isoform of ZAP coordinates multiple enzymes to mediate complete decay of target transcripts. | Cell Rep | 2026 | 42054207 | PubTator, text mining | PubMed |
1 to 10 of 1,573
See all 1,573 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/56829
GET https://conductscience.org/api/genes/v1/56829/patents