ConductScience.org, home

Gene · 5688

PSMA7: proteasome 20S subunit alpha 7

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. PSMA7: proteasome 20S subunit alpha 7. Genes, record 5688. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5688

On this page

Gene

Symbol
PSMA7
HGNC
Name
proteasome 20S subunit alpha 7
HGNC
NCBI Gene ID
5688
NCBI Gene
HGNC ID
HGNC:9536
HGNC
Ensembl
ENSG00000101182
NCBI Gene
Aliases
C6, HEL-S-276, HSPC, RC6-1, XAPC7
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O14818Proteasome subunit alpha type-7248177Ensembl, GeneID, HGNC

Source UniProt

Patents53

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1459525O14818Espacenet
EP 4650780 A22025-11-198857O14818Espacenet
JP 2025517970 A2025-06-128857O14818Espacenet
US 11694765 B22023-07-04186O14818Espacenet
US 11446398 B22022-09-2067893O14818Espacenet
JP 2022524081 A2022-04-27170864O14818Espacenet
US 11078247 B22021-08-039061O14818Espacenet
US 11047010 B22021-06-293125O14818Espacenet
US 10865447 B22020-12-153125O14818Espacenet
JP 2020072653 A2020-05-14307O14818Espacenet

1 to 10 of 53

See all 53 patents

Drugs7

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
BORTEZOMIBCHEMBL32504126S proteasome inhibitorINHIBITORChEMBL
BORTEZOMIB D-MANNITOLCHEMBL531512226S proteasome inhibitorINHIBITORChEMBL
CARFILZOMIBCHEMBL45188726S proteasome inhibitorINHIBITORChEMBL
IXAZOMIBCHEMBL214129626S proteasome inhibitorINHIBITORChEMBL
IXAZOMIB CITRATECHEMBL354543226S proteasome inhibitorINHIBITORChEMBL
MARIZOMIBCHEMBL37140520S proteasome inhibitorINHIBITORChEMBL
OPROZOMIBCHEMBL210388426S proteasome inhibitorINHIBITORChEMBL

Trials1,241

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07605416CARFILZOMIBPHASE2ClinicalTrials.gov
NCT07601100BORTEZOMIBPHASE1/PHASE2ClinicalTrials.gov
NCT07600151BORTEZOMIBPHASE1/PHASE2ClinicalTrials.gov
NCT07513129BORTEZOMIBPHASE1ClinicalTrials.gov
NCT07479979CARFILZOMIBPHASE1/PHASE2ClinicalTrials.gov
NCT07464210BORTEZOMIBPHASE2ClinicalTrials.gov
NCT07463807CARFILZOMIBPHASE1/PHASE2ClinicalTrials.gov
NCT07428369BORTEZOMIBPHASE2/PHASE3ClinicalTrials.gov
NCT07391657BORTEZOMIBPHASE3ClinicalTrials.gov
NCT07391657CARFILZOMIBPHASE3ClinicalTrials.gov

1 to 10 of 1,241

See all 1,241 trials

NIH grants851

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePSMA7 papersNewest fiscal year
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control72025
P30CA008748Cancer Center Support Grant62025
U54DK106829Stem Cell and Transplantation Biology42025
RM1HG009490Center for Genomic Editing and Recording: Development and Application of Next-Generation Genome and Epigenome Editing Methods to Advance the Study and Treatment of Human Disease32025
ZICES102445Gene Expression and Microarrays32025
P30AI027763UCSF-Bay Area Center for AIDS Research22025
P30CA016086Cancer Center Support Grant22025
P30CA021765Cancer Center Support Grant (CCSG)22025
R01DK103794Systematic Genetic Dissection of Human Erythropoiesis22025
R35GM122480Proteomics and model organism humanization to decode human genetics22025

1 to 10 of 851Source NIH's project files

See all 851 nih grants

Papers1,135

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Homo-aro-cholestane glycosides from Ypsilandra thibetica modulate the expansion of human cord blood hematopoietic stem and progenitor cells.Bioorg Chem202642772100PubTator, text miningPubMed
Differential analysis of urinary stable downregulated proteins in male patients after colorectal cancer surgery.Front Oncol202642707234PubTator, text miningPubMed
Hyaluronic acid-phosphatidylcholine complexes as reductionist mimics of extracellular vesicle-mediated boundary lubrication in synovial joints.Acta Biomater202642034303PubTator, text miningPubMed
Multi-omic profiling converges on proteasome subunits PSMA7/PSMB2 as targets of the sepsis-protective agent Handelin.Front Immunol202641939900PubTator, text miningPubMed
Integrative analysis of the PSMA family identifies PSMA6 as an adverse prognostic biomarker promoting bladder cancer cell proliferation.Int J Med Sci202641799753PubTator, text miningPubMed
Biomimetic Cell Membrane-coated Nanovaccines in Anti-tumor Immunotherapy.Theranostics202641799199PubTator, text miningPubMed
Microfluidic Nanocomposite Lubricating Microgels Localized Deliver Celastrol for Remodeling the Immune Microenvironment to Enhance Osteoarthritis Treatment.Research (Wash D C)202641767600PubTator, text miningPubMed
Lactylation-based machine algorithm combined with multi-omics analysis to predict prognosis in cervical cancer.Oncol Lett202641743011PubTator, text miningPubMed
Proteomic Analysis of Human Chronic Traumatic Encephalopathy Brain Implicates Proteasome and Ribosome Dysfunction in Disease Progression.bioRxiv202641726919PubTator, text miningPubMed
Matrix stiffness induces Ca2+-DCLK1-PIP5K1A mechanotransduction as a context-specific amplifier in pancreatic cancer progression and chemotherapy resistance.Exp Hematol Oncol202641692802PubTator, text miningPubMed

1 to 10 of 1,135

See all 1,135 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5688

GET https://conductscience.org/api/genes/v1/5688/patents?page=2