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Gene · 56896

DPYSL5: dihydropyrimidinase like 5

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. DPYSL5: dihydropyrimidinase like 5. Genes, record 56896. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/56896

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Gene

Symbol
DPYSL5
HGNC
Name
dihydropyrimidinase like 5
HGNC
NCBI Gene ID
56896
NCBI Gene
HGNC ID
HGNC:20637
HGNC
Ensembl
ENSG00000157851
NCBI Gene
Aliases
CRAM, CRMP-5, CRMP5, CV2, RTSC4, Ulip6
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9BPU6Dihydropyrimidinase-related protein 55643Ensembl, GeneID, HGNC

Source UniProt

Patents35

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1443799Q9BPU6Espacenet
JP 2026004568 A2026-01-1443800Q9BPU6Espacenet
EP 4641201 A22025-10-292946Q9BPU6Espacenet
JP 2025517969 A2025-06-122946Q9BPU6Espacenet
US 11446398 B22022-09-2024408Q9BPU6Espacenet
US 11446398 B22022-09-2024409Q9BPU6Espacenet
US 11446398 B22022-09-2024413Q9BPU6Espacenet
JP 2022524081 A2022-04-27127379Q9BPU6Espacenet
JP 2022524081 A2022-04-27127380Q9BPU6Espacenet
JP 2022524081 A2022-04-27127384Q9BPU6Espacenet

1 to 10 of 35

See all 35 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants415

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDPYSL5 papersNewest fiscal year
R01NS126227Seronegative Autoimmune Encephalopathies: Biomarker Discovery, Validation & Deep Phenotyping72025
UL1TR001863Yale Clinical and Translational Science Award62025
R01NS119263Anti-CV2 autoantibodies unmask a CRMP5/GluN2B pain signaling hub32025
K12EY021475UIC K12 independent Clinical Vision Scientist Development Program22025
P30CA008748Cancer Center Support Grant22025
P30CA068485Cancer Center Support Grant22025
P30EY010572Ophthalmology Core Facility22025
R35NS116843Continuous Neurogenesis in the Mammalian Hippocampus22025
R35NS137480Epitranscriptomic regulation in the mammalian nervous system22025
T32CA009531Training Program in the Biology of Cancer22025

1 to 10 of 415Source NIH's project files

See all 415 nih grants

Papers1,315

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Myasthenia gravis with thymoma-associated CRMP5/CV2 antibody-positive paraneoplastic neurological syndrome: a case report and literature review.Front Immunol202642807089PubTator, text miningPubMed
Spatially Contextualized Integrative Genomics Highlights Neuronal and Glial Regulatory Programs in Low Back Pain.J Pain Res202642699694PubTator, text miningPubMed
Correlation between Antiretinal Antibodies and OCT Manifestations in Nonparaneoplastic Autoimmune Retinopathy.Ophthalmol Sci202642437120PubTator, text miningPubMed
Glucocorticoid Signaling in PSC-Derived Neural Systems to Elucidate Mechanisms of Stress-Induced Psychiatric Vulnerability.Mol Neurobiol202642412256PubTator, text miningPubMed
Clinical features, imaging findings, and treatment outcomes of optic neuritis associated with anti-CRMP5 antibodies: a systematic review.J Neuroimmunol202642372569PubTator, text miningPubMed
Architects of the Developing Brain: Cytoskeleton-Organizing Molecules in Neurodevelopmental Disorders.Cells202641892327PubTator, text miningPubMed
Mixed Signals and Interspecies Variation in the Plasticity of Adult Mammal Brains.Cells202641892311PubTator, text miningPubMed
Integrative genomic and spatial transcriptomic analysis elucidates the oligodendrocyte-mediated etiology of epileptic cortical thinning.Epilepsia Open202641885647PubTator, text miningPubMed
Paraneoplastic neuromyelitis optica spectrum disorder with dual AQP4-IgG and CRMP5 antibodies following thymectomy: a case report.Front Neurosci202641878006PubTator, text miningPubMed
Morvan syndrome in a patient with progressing metastatic thymoma and myasthenia gravis.BMJ Case Rep202641856686PubTator, text miningPubMed

1 to 10 of 1,315

See all 1,315 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/56896

GET https://conductscience.org/api/genes/v1/56896/patents?page=2