Gene · 56947
MFF: mitochondrial fission factor
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. MFF: mitochondrial fission factor. Genes, record 56947. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/56947
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9GZY8 | Mitochondrial fission factor | 342 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents20
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2025529142 A | 2025-09-04 | 2607 | Q9GZY8 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 2607 | Q9GZY8 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 31505 | Q9GZY8 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 31505 | Q9GZY8 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 31505 | Q9GZY8 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 51825 | Q9GZY8 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 4615 | Q9GZY8 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 154796 | Q9GZY8 | Espacenet |
| JP 2020508652 A | 2020-03-26 | 31505 | Q9GZY8 | Espacenet |
| JP 2017121240 A | 2017-07-13 | 51855 | Q9GZY8 | Espacenet |
1 to 10 of 20
See all 20 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,119
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MFF papers | Newest fiscal year |
|---|---|---|---|
| R35GM122545 | The impact of dynamic actin polymerization on mitochondrial dynamics and function | 7 | 2025 |
| P20GM113132 | The Institute for Biomolecular Targeting | 6 | 2025 |
| P30CA014195 | Cancer Center Support Grant (CCSG) | 6 | 2025 |
| R01GM125844 | Defining Molecular Interactions that Drive Mitochondrial Fission | 6 | 2025 |
| ZIANS003123 | Role of mitochondria in neurodegenerative diseases | 5 | 2025 |
| P01CA120964 | Molecular Pathogenesis of the Hamartoma Syndromes | 4 | 2025 |
| R01AA011147 | Ethanol and aldehyde dehydrogenases in health and disease | 4 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 3 | 2025 |
| P30CA012197 | Cancer Center Support Grant | 3 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 1,119Source NIH's project files
See all 1,119 nih grantsPapers1,634
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Mitochondrial Quality Control: A Gatekeeper of Spermatogenesis. | J Vis Exp | 2026 | 42813713 | PubTator, text mining | PubMed |
| Recent advances in mitochondrial fission and fusion in diabetic cardiomyopathy. | Front Cardiovasc Med | 2026 | 42761440 | PubTator, text mining | PubMed |
| Mitochondrial fission factor senses and governs ferroptosis. | Nature | 2026 | 42749797 | PubTator, text mining | PubMed |
| Spire1 and active INF2 promote ER-mitochondria contacts to enhance mitochondrial fission factor-mediated mitochondrial fission. | FEBS J | 2026 | 42741824 | PubTator, text mining | PubMed |
| The identification of Drp1 patient mutations that limit interactions with Mff. | Mol Biol Cell | 2026 | 42555829 | PubTator, text mining | PubMed |
| Mitochondrial-derived vesicles drive budding-type fission of damaged lysosomes. | Nat Cell Biol | 2026 | 42477140 | PubTator, text mining | PubMed |
| AMPK activation by AICAR mitigates hypoxic corneal damage through rebuilding energy and metabolic homeostasis. | Chem Biol Interact | 2026 | 42392248 | PubTator, text mining | PubMed |
| Role of recombinant S100A13 expression in regulating mitochondrial fission and fusion in lung epithelial cells. | BBA Adv | 2026 | 42328016 | PubTator, text mining | PubMed |
| Unraveling the effector mechanism of citrulline on sow lactation and offspring growth: an integrative multi-omics analysis. | J Anim Sci Biotechnol | 2026 | 42298669 | PubTator, text mining | PubMed |
| MFF Promotes Aggressive Phenotypes and Immunosuppression in Lung Adenocarcinoma via Mitochondrial Dysregulation. | Curr Med Chem | 2026 | 42220150 | PubTator, text mining | PubMed |
1 to 10 of 1,634
See all 1,634 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/56947
GET https://conductscience.org/api/genes/v1/56947/patents