Gene · 57007
ACKR3: atypical chemokine receptor 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ACKR3: atypical chemokine receptor 3. Genes, record 57007. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/57007
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P25106 | Atypical chemokine receptor 3 | 362 | 14 | Ensembl, GeneID, HGNC |
Source UniProt
Patents117
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026062654 A | 2026-04-10 | 34 | P25106 | Espacenet |
| JP 2026504180 A | 2026-02-03 | 4 | P25106 | Espacenet |
| JP 2026504180 A | 2026-02-03 | 5 | P25106 | Espacenet |
| EP 4680730 A2 | 2026-01-21 | 21 | P25106 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 41102 | P25106 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 2838 | P25106 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 16715 | P25106 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 234 | P25106 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 234 | P25106 | Espacenet |
| JP 2025522558 A | 2025-07-15 | 244 | P25106 | Espacenet |
1 to 10 of 117
See all 117 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,255
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ACKR3 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 11 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 9 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 9 | 2025 |
| R37AI058072 | Structural Basis for Chemokine Function | 9 | 2025 |
| P30CA046592 | University of Michigan Rogel Cancer Center Support Grant 2023-2028 | 8 | 2025 |
| R01AI161880 | It's a tug of war: structure, consequences, and inhibition of CXCR4 and ACKR3 responses to lymphocyte chemoattractant CXCL12 | 8 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 7 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 6 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 6 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 6 | 2025 |
1 to 10 of 2,255Source NIH's project files
See all 2,255 nih grantsPapers3,960
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| The CXCL12γ/ACKR3 Axis Is a Critical Determinant of Myocardial Angiogenesis and Functional Recovery After Infarction. | JACC Basic Transl Sci | 2026 | 42804830 | PubTator, text mining | PubMed |
| Combined detection of CXCR7 and CXCL12 for diagnosing acute myocardial infarction and predicting post-percutaneous coronary intervention major adverse cardiovascular events. | J Med Biochem | 2026 | 42781331 | PubTator, text mining | PubMed |
| Coordinated inflammatory macrophage and vascular smooth muscle cell remodeling signatures in human atherosclerosis: An integrative single-cell and bulk transcriptomic analysis. | J Cell Commun Signal | 2026 | 42695089 | PubTator, text mining | PubMed |
| Proadrenomedullin N-Terminal 20 Peptide (PAMP) Increases Proliferation and Induces Cytoskeleton Remodeling in Melanoma Cells Through the CXCR7/CXCR4/β-Arrestin Axis. | Molecules | 2026 | 42653874 | PubTator, text mining | PubMed |
| Single-cell transcriptomics reveals a correlation between inflammatory C7 fibroblasts in cervical tumor-adjacent normal tissues and cervical cancer progression. | Front Cell Dev Biol | 2026 | 42638795 | PubTator, text mining | PubMed |
| CXCL12/CXCR4 signaling governs ischemic neurovascular pathophysiology and repair: a multidimensional contextual analysis. | Angiogenesis | 2026 | 42625089 | PubTator, text mining | PubMed |
| KLF4 in Smooth Muscle Cell-Derived Progenitor Cells Is Essential for Angiotensin II-Induced Cardiac Inflammation and Fibrosis. | Arterioscler Thromb Vasc Biol | 2026 | 42619593 | PubTator, text mining | PubMed |
| Identification of Entacapone as a Novel β-Arrestin 1 Biased Antagonist of CXCR7. | Molecules | 2026 | 42588455 | PubTator, text mining | PubMed |
| Age- and sex-related differences in physiological rotation patterns of the cervical spine: A detailed upright multidetector CT analysis. | J Orthop Sci | 2026 | 42570901 | PubTator, text mining | PubMed |
| Comprehensive In Silico Analysis of the CXCL12, C55Y Mutation Reveals Structural and Functional Disruption in CXCR4/CXCR7 Signaling. | Evol Bioinform Online | 2026 | 42564356 | PubTator, text mining | PubMed |
1 to 10 of 3,960
See all 3,960 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/57007
GET https://conductscience.org/api/genes/v1/57007/patents?page=2