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Gene · 571

BACH1: BACH transcriptional regulator 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. BACH1: BACH transcriptional regulator 1. Genes, record 571. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/571

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Gene

Symbol
BACH1
HGNC
Name
BACH transcriptional regulator 1
HGNC
NCBI Gene ID
571
NCBI Gene
HGNC ID
HGNC:935
HGNC
Ensembl
ENSG00000156273
NCBI Gene
Aliases
BACH-1, BTBD24
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O14867Transcription regulator protein BACH173612Ensembl, GeneID, HGNC

Source UniProt

Patents55

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1439278O14867Espacenet
JP 2026004568 A2026-01-1439279O14867Espacenet
EP 4650780 A22025-11-193307O14867Espacenet
EP 4641201 A22025-10-292881O14867Espacenet
JP 2025147176 A2025-10-0614779O14867Espacenet
WO 2025173787 A2025-08-216O14867Espacenet
JP 2025517969 A2025-06-122881O14867Espacenet
JP 2025517970 A2025-06-123307O14867Espacenet
JP 2025062604 A2025-04-149994O14867Espacenet
JP 2025062604 A2025-04-149995O14867Espacenet

1 to 10 of 55

See all 55 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,920

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleBACH1 papersNewest fiscal year
ZIAAG000741Roles Of DNA Helicases In Pathways Required For Maintenance Of Genomic Stability252025
ZIAAG000753Fanconi Anemia Pathway252025
ZIAAG000752Model Genetic Systems to Study DNA Repair162025
P01CA092584Structural Cell Biology of DNA Repair Machines132025
P30CA008748Cancer Center Support Grant82025
R01DK050107Transcriptional Control of Hemoglobin Synthesis and Erythrocyte Development82025
T32AG052374USC-Buck Geroscience Training in the Biology of Aging82025
P30CA016672Cancer Center Support Grant62025
P30ES001247Environmental Agents as Modulators of Disease Processes62025
P50CA116201Mayo Clinic Breast Cancer SPORE62025

1 to 10 of 1,920Source NIH's project files

See all 1,920 nih grants

Papers2,758

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
HBx Enhances the Nrf2/ARE-dependent Antioxidant Response by Promoting Nuclear Export and Downregulation of Bach1.Kobe J Med Sci202642805912PubTator, text miningPubMed
Ferroptosis-driven cell death perpetuates the chronic inflammatory cycle in periodontitis: a single-cell transcriptomic study.Front Cell Dev Biol202642780883PubTator, text miningPubMed
Cell type-specific histone acetylation landscape in Alzheimer's disease reveals a putative role of MITF in microglia.bioRxiv202642779635PubTator, text miningPubMed
Heme as a versatile signaling molecule: Coordinating mitochondrial metabolism with global cellular responses.J Biol Chem202642705539PubTator, text miningPubMed
Structural and thermodynamic analysis of BRCA1 BRCT variants identified in Middle Eastern breast cancer cohorts.Protein Pept Lett202642692369PubTator, text miningPubMed
Endothelial EPAS1 as a prognostic and therapeutic target in acute myocardial infarction: integrative bioinformatics, Mendelian randomization and experimental validation.Front Pharmacol202642614148PubTator, text miningPubMed
BACH1/HO-1 axis dysregulation links Down syndrome to Alzheimer-like neurodegeneration.Neurochem Int202642532345PubTator, text miningPubMed
Elevated BACH1 Contributes to Mitochondrial Succinylome Remodeling and Trophoblast Bioenergetic Dysfunction in Preeclampsia.Antioxidants (Basel)202642510566PubTator, text miningPubMed
Targeting the hsa-miR-155-5p-BACH1-MMP-9 Signaling Hub in Lung Cancer: A Novel Anticancer Mechanism of Thymoquinone.Biomolecules202642509749PubTator, text miningPubMed
Clinical Relevance of BACH1 Expression in Non-Small Cell Lung Cancer.Int J Cancer202642503861PubTator, text miningPubMed

1 to 10 of 2,758

See all 2,758 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/571

GET https://conductscience.org/api/genes/v1/571/patents?page=2