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PNPLA2: patatin like domain 2, triacylglycerol lipase
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Gene · 57104

Papers3,807

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

81 to 100 of 3,807

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TitleJournalYearPMIDFound bySource
YY1 nitration participates in DbCM cardiomyocyte lipotoxicity by inhibiting ANXA3-induced microlipophagy.Redox Biol202641702019PubTator, text miningPubMed
Lipid metabolism in homeostasis and disease.Signal Transduct Target Ther202641692800PubTator, text miningPubMed
Interplay between obesity-associated insulin resistance and immune system through the lens of evolutionary medicine.Mol Metab202641692338PubTator, text miningPubMed
MTARC1 Inactivation Remodels Lipid Droplets to Protect Against Metabolic Fatty Liver Disease.Liver Int202641641916PubTator, text miningPubMed
Neutral Lipid Storage Disease with Myopathy: A Case Report with a Novel PNPLA2 Mutation.Ann Indian Acad Neurol202641622608PubTator, text miningPubMed
Effects of dietary nanoplastics exposure on muscle quality, immunity, antioxidative capacity and digestive gland function of abalone (Haliotis discus hannai).Aquat Toxicol202641621143PubTator, text miningPubMed
Patatin-domain-containing (phospho)lipases under control: Mammalian co-regulators and pathogenic activation mechanisms.FEBS Open Bio202641618727PubTator, text miningPubMed
Dietary fucoidan supplementation ameliorates heat stress-induced liver injury in broilers via modulating peroxidation, lipid metabolism, and ferroptosis.Poult Sci202641587525PubTator, text miningPubMed
Aging, oxidative stress, and cataracts: Therapeutic prospects and translational insights into peroxiredoxin 6.Prog Retin Eye Res202641577330PubTator, text miningPubMed
Acetyl-CoA acyltransferase 2 palmitoylation drives liver fibrosis by inducing hepatic stellate cell ferroptosis.Redox Biol202641564793PubTator, text miningPubMed
A PNPLA3-NACC1-RIPK3 pathway mediates macrophage necroptosis and inflammation in MASLD.Hepatol Commun202641564367PubTator, text miningPubMed
Peripheral Administration of Hypertonic Saline Affects Nutrient Metabolism-related Gene Expression in Chicks.J Poult Sci202641551864PubTator, text miningPubMed
Arachidonic acid analog AACOCF3 suppresses cPLA2-negative NSCLC cell proliferation by targeting SSRP1 to activate the IFNα/β pathway.Biochem Pharmacol202641544858PubTator, text miningPubMed
An Adcy3 coding mutation causes partial loss of enzymatic function, contributing to obesity in a rat model by reducing lipolysis.Res Sq202641542040PubTator, text miningPubMed
Cancer cachexia: molecular basis and therapeutic advances.Signal Transduct Target Ther202641526343PubTator, text miningPubMed
Gut Microbiota-Derived Propionic Acid Mediates ApoA-I-Induced Amelioration of MASLD via Activation of GPR43-Ca2+-CAMKII-ATGL Hepatic Lipolysis.Int J Mol Sci202641516340PubTator, text miningPubMed
ATGL suppresses ferroptosis in acute myeloid leukemia cells by modulating the CEBPα/SCD1 axis and induces gilteritinib resistance.Cell Death Dis202641513623PubTator, text miningPubMed
Association between PNPLA3 rs738409 and susceptibility to etiology-specific liver cirrhosis: a systematic review and meta-analysis.BMC Med Genomics202641491174PubTator, text miningPubMed
Organelle-specific regulation of ferroptosis.Biol Direct202641484993PubTator, text miningPubMed
Cytosolic Versus Lysosomal Lipolysis in Adipose Tissue: Opposing Roles in Cardiometabolic Disease.Arterioscler Thromb Vasc Biol202641431923PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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