Gene · 57126
CD177: CD177 molecule
12 sourcesgene-search-2026-11-11-0.2.0
Download JSON
Cite this record
ConductScience Library. CD177: CD177 molecule. Genes, record 57126. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/57126
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q8N6Q3 | CD177 antigen | 437 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents8
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2025529142 A | 2025-09-04 | 5766 | Q8N6Q3 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 5766 | Q8N6Q3 | Espacenet |
| JP 2023519304 A | 2023-05-10 | 142 | Q8N6Q3 | Espacenet |
| KR 1020220160053 A | 2022-12-05 | 130 | Q8N6Q3 | Espacenet |
| WO 2015182580 A | 2015-12-03 | 3 | Q8N6Q3 | Espacenet |
| WO 2012169887 A2 | 2012-12-13 | 10 | Q8N6Q3 | Espacenet |
| JP 2010534828 A | 2010-11-11 | 3 | Q8N6Q3 | Espacenet |
| WO 2009013319 A1 | 2009-01-29 | 1 | Q8N6Q3 | Espacenet |
Drugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,218
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CD177 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 13 | 2025 |
| P01CA108671 | Myeloproliferative Neoplasms-Research Consortium | 7 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| P20GM103427 | Nebraska Research Network in Functional Genomics | 4 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 4 | 2025 |
| P30DK020572 | Michigan Diabetes Research Center (MDRC) | 4 | 2025 |
| T32GM008721 | Molecular Biology in Burns and Trauma | 4 | 2025 |
| P30AG028740 | University of Florida Older Americans Independence Center (OAIC) | 3 | 2025 |
| P30AR070253 | Joint Biology Consortium Resource-based Center | 3 | 2025 |
| P30CA014520 | UW Comprehensive Cancer Center Support | 3 | 2025 |
1 to 10 of 2,218Source NIH's project files
See all 2,218 nih grantsPapers3,864
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
Pre-transplant whole blood transcriptomic profiling identifies mRNAs linked to cirrhosis-associated immune dysfunction as candidate predictors of clinical outcomes after liver transplantation: an exploratory study. | Transpl Int | 2026 | 42729608 | PubTator, text mining | PubMed |
| Identification of Critical Genes for Recurrent Aphthous Ulcer by Transcriptome Data Analysis and Mendelian Randomization. | Oral Health Prev Dent | 2026 | 42714320 | PubTator, text mining | PubMed |
| Peripheral blood microarray-based transcriptomic and epigenetic analyses identify immune, inflammation, and metabolic dysregulation in Alzheimer's disease. | NPJ Dement | 2026 | 42687894 | PubTator, text mining | PubMed |
| A skin-kidney neutrophil axis links ultraviolet exposure to renal angiogenesis and tissue remodeling in healthy and lupus kidneys. | J Immunol | 2026 | 42679049 | PubTator, text mining | PubMed |
| Transcriptomic Markers of Immunosenescence in Cynomolgus Macaques: A Pilot Study. | Genes (Basel) | 2026 | 42650137 | PubTator, text mining | PubMed |
| Inhibition of salt-inducible kinases 2 and 3 reduces inflammatory signature in psoriasis. | J Invest Dermatol | 2026 | 42612789 | PubTator, text mining | PubMed |
| Restricted TCR Diversity and Expansion of CD177+CD8+ and TLR4+CD4+T Cell Subsets in Septic Shock-Associated Immunosuppression: A Single-Cell Multi-Omics Study. | MedComm (2020) | 2026 | 42609522 | PubTator, text mining | PubMed |
| The C5a-C5aR1 axis facilitates blood-brain barrier disruption induced by EV-A71 infection through neutrophil activation. | PLoS Pathog | 2026 | 42555657 | PubTator, text mining | PubMed |
| TGF-β1 drives neutrophil extracellular traps formation to promote CD8+ T cell exhaustion via the ERK-c-Fos-JunB axis, mediating gastric cancer immunotherapy resistance. | J Immunother Cancer | 2026 | 42552060 | PubTator, text mining | PubMed |
| Upregulated CD177 on neutrophils is implicated in sepsis pathogenesis and necroptosis-driven inflammation. | Front Immunol | 2026 | 42490847 | PubTator, text mining | PubMed |
1 to 10 of 3,864
See all 3,864 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/57126
GET https://conductscience.org/api/genes/v1/57126/grants?page=2