ConductScience.org, home

Library / Genes

PTBP1: polypyrimidine tract binding protein 1

1 protein, 31 patents, 0 drugs, 0 trials, 3,146 NIH grants and 5,578 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPTBP1HGNC
Namepolypyrimidine tract binding protein 1HGNC
NCBI Gene ID5725NCBI Gene
HGNC IDHGNC:9583HGNC
EnsemblENSG00000011304NCBI Gene
AliasesHNRNP-I, HNRNPI, HNRPI, PTB, PTB-1, PTB-T, PTB2, PTB3, PTB4, STADS, pPTBNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P26599Polypyrimidine tract-binding protein 155713Ensembl, GeneID, HGNCUniProt

Patents 31

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1458513P26599Espacenet
EP 4650780 A22025-11-197371P26599Espacenet
JP 2025517970 A2025-06-127371P26599Espacenet
US 12186353 B22025-01-0714P26599Espacenet
US 11694765 B22023-07-04286P26599Espacenet
US 11446398 B22022-09-2065284P26599Espacenet
JP 2022524081 A2022-04-27168255P26599Espacenet
EP 3890771 A12021-10-1314P26599Espacenet
US 11078247 B22021-08-039104P26599Espacenet
JP 2020072653 A2020-05-14357P26599Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3146

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant232,025NIH's project files
P30CA008748Cancer Center Support Grant192,025NIH's project files
ZIAAG000511Post-transcriptional control of Proliferation, Stress Response & Carcinogenesis122,025NIH's project files
R35GM118048Signal-Induced Regulation of Alternative RNA Processing102,025NIH's project files
P01CA013106Targeting Transcription and Splicing in Cancer92,025NIH's project files
P30CA016058Cancer Center Support Grant82,025NIH's project files
P30CA045508CSHL Cancer Center Support Grant82,025NIH's project files
ZIAHL006158Mechanisms of nonsense-mediated mRNA decay target selection82,025NIH's project files
P30ES017885Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD)72,025NIH's project files
R01NS055251Voltage-Gated Calcium Channels in Nociceptors and Mechanoreceptors72,025NIH's project files

Papers 5578

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818787PubTator, text miningPubMed
42803655PubTator, text miningPubMed
42801686PubTator, text miningPubMed
42792595PubTator, text miningPubMed
42791954PubTator, text miningPubMed
42790162PubTator, text miningPubMed
42759326PubTator, text miningPubMed
42742668PubTator, text miningPubMed
42739211PubTator, text miningPubMed
42728347PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license