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PTCH1: patched 1

1 protein, 50 patents, 0 drugs, 0 trials, 4,224 NIH grants and 8,554 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPTCH1HGNC
Namepatched 1HGNC
NCBI Gene ID5727NCBI Gene
HGNC IDHGNC:9585HGNC
EnsemblENSG00000185920NCBI Gene
AliasesBCNS, BCNS1, NBCCS, PTC, PTC1, PTCH, SLC65B1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q13635Protein patched homolog 11,44716Ensembl, GeneID, HGNCUniProt

Patents 50

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4705273 A22026-03-11205Q13635Espacenet
EP 4641201 A22025-10-295697Q13635Espacenet
JP 2025529142 A2025-09-043609Q13635Espacenet
US 12371689 B22025-07-293609Q13635Espacenet
JP 2025517969 A2025-06-125697Q13635Espacenet
JP 2025013347 A2025-01-24205Q13635Espacenet
JP 2024123008 A2024-09-107537Q13635Espacenet
EP 4406585 A22024-07-31205Q13635Espacenet
US 11725217 B22023-08-152Q13635Espacenet
US 11649272 B22023-05-1644Q13635Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4224

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant692,025NIH's project files
P30CA008748Cancer Center Support Grant682,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)502,025NIH's project files
P01CA096832NORMAL & NEOPLASTIC GROWTH IN THE BRAIN462,025NIH's project files
R01CA159859Dysregulation of the Core Binding Factor Complex Inhibits Differentiation and Drives Group 4 Medulloblastoma362,025NIH's project files
P30CA006973Regional Oncology Research Center262,025NIH's project files
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-2028262,025NIH's project files
R01AR046786Stromal Regulation of Basal Cell Carcinoma Formation222,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant202,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award172,025NIH's project files

Papers 8554

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818167PubTator, text miningPubMed
42805854PubTator, text miningPubMed
42720515PubTator, text miningPubMed
42715142PubTator, text miningPubMed
42712018PubTator, text miningPubMed
42707049PubTator, text miningPubMed
42680131PubTator, text miningPubMed
42667406PubTator, text miningPubMed
42658353PubTator, text miningPubMed
42650114PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license