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Gene · 5730

PTGDS: prostaglandin D2 synthase

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. PTGDS: prostaglandin D2 synthase. Genes, record 5730. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/5730

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
PTGDS
HGNC
Name
prostaglandin D2 synthase
HGNC
NCBI Gene ID
5730
NCBI Gene
HGNC ID
HGNC:9592
HGNC
Ensembl
ENSG00000107317
NCBI Gene
Aliases
L-PGDS, LPGDS, PDS, PGD2, PGDS, PGDS2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P41222Prostaglandin-H2 D-isomerase19017Ensembl, GeneID, HGNC

Source UniProt

Patents72

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026028973 A2026-02-055P41222Espacenet
JP 2026004568 A2026-01-1459396P41222Espacenet
JP 2026004568 A2026-01-1459400P41222Espacenet
EP 4650780 A22025-11-198983P41222Espacenet
JP 2025147176 A2025-10-0611041P41222Espacenet
JP 2025529142 A2025-09-047486P41222Espacenet
US 12371689 B22025-07-297486P41222Espacenet
JP 2025517970 A2025-06-128983P41222Espacenet
JP 2025028160 A2025-02-2811041P41222Espacenet
KR 1020250010750 A2025-01-2111041P41222Espacenet

1 to 10 of 72

See all 72 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
ANTRAFENINECHEMBL345524Prostaglandin-H2 D-isomerase inhibitorINHIBITOR

Source ChEMBL

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,333

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
U19AI095219Pathophysiologic and Therapeutic Mechanisms of Aspirin Exacerbated Respiratory Disease192025
T32AI007306Immunologic Basis of Resistance and Hypersensitivity162025
R01AI078908Control of Pulmonary Inflammation by Leukotriene E4152025
T32HL007024Cardiovascular Epidemiology Institutional Training112025
U19AI070535Airway Inflammation and Airway Remodeling in Severe Asthma102025
P30ES013508Center of Excellence in Environmental Toxicology92025
R01AI136041Eicosanoid Networks in Aspirin Hypersensitivity92025
U01DK060984Prospective renal insufficiency cohort evaluation: PRICE82025
ZIAAI000249The Pathogenesis, Diagnosis, and Treatment of Systemic Mast Cell Disorders82025
U01DK060902Chronic Renal Insufficiency Cohort (CRIC) Study Clinical Center72025

1 to 10 of 2,333Source NIH's project files

See all 2,333 nih grants

Papers4,402

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42755176PubTator, text miningPubMed
42742904PubTator, text miningPubMed
42723880PubTator, text miningPubMed
42680028PubTator, text miningPubMed
42628887PubTator, text miningPubMed
42610087PubTator, text miningPubMed
42609827PubTator, text miningPubMed
42605717PubTator, text miningPubMed
42512007PubTator, text miningPubMed
42509739PubTator, text miningPubMed

1 to 10 of 4,402

See all 4,402 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

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GET https://conductscience.org/api/genes/v1/5730/patents?page=2