Gene · 5731
PTGER1: prostaglandin E receptor 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PTGER1: prostaglandin E receptor 1. Genes, record 5731. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5731
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P34995 | Prostaglandin E2 receptor EP1 subtype | 402 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents23
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026062654 A | 2026-04-10 | 46 | P34995 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 59401 | P34995 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 3619 | P34995 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 3619 | P34995 | Espacenet |
| EP 4491229 A2 | 2025-01-15 | 206 | P34995 | Espacenet |
| WO 2024230934 A1 | 2024-11-14 | 331 | P34995 | Espacenet |
| JP 2023156353 A | 2023-10-24 | 46 | P34995 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 67453 | P34995 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 342 | P34995 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 170424 | P34995 | Espacenet |
1 to 10 of 23
See all 23 patentsDrugs3
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials37
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT07601646 | ALPROSTADIL | PHASE2 | ClinicalTrials.gov | |
| NCT06768177 | ALPROSTADIL | ClinicalTrials.gov | ||
| NCT05774236 | DINOPROSTONE | PHASE3 | ClinicalTrials.gov | |
| NCT05761418 | DINOPROSTONE | PHASE3 | ClinicalTrials.gov | |
| NCT05342467 | DINOPROSTONE | PHASE2 | ClinicalTrials.gov | |
| NCT04536363 | ALPROSTADIL | PHASE2 | ClinicalTrials.gov | |
| NCT04505943 | DINOPROSTONE | ClinicalTrials.gov | ||
| NCT04505917 | DINOPROSTONE | ClinicalTrials.gov | ||
| NCT04301349 | DINOPROSTONE | PHASE3 | ClinicalTrials.gov | |
| NCT04299854 | DINOPROSTONE | ClinicalTrials.gov |
1 to 10 of 37
See all 37 trialsNIH grants1,217
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PTGER1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 10 | 2025 |
| R01NS100947 | Inflammatory regulation of epileptogenesis after status epilepticus | 8 | 2025 |
| R01HL058506 | G Protein-Coupled Receptor Regulation in Airway Myocytes | 7 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 6 | 2025 |
| P30CA134274 | UNIVERSITY OF MARYLAND GREENEBAUM CANCER CENTERSUPPORT GRANT | 6 | 2025 |
| P30ES005605 | Environmental Health Sciences Research Center | 5 | 2025 |
| P30CA086862 | Cancer Center Support Grant | 4 | 2025 |
| P30ES006694 | Southwest Environmental Health Sciences Center | 4 | 2025 |
| P42ES013661 | Iowa Superfund Research Program: Airborne PCBs: Sources, Exposures, Toxicities, Remediation | 3 | 2025 |
| R01AI078908 | Control of Pulmonary Inflammation by Leukotriene E4 | 3 | 2025 |
1 to 10 of 1,217Source NIH's project files
See all 1,217 nih grantsPapers2,455
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Development of sustainable natural waste-reinforced epoxy composites for potential building applications. | RSC Adv | 2026 | 42644081 | PubTator, text mining | PubMed |
| A Three-Dimensional Hyaluronic Acid-Based Scaffold Model for Electroporation-Enhanced Resveratrol Therapy in Triple-Negative Breast Cancer. | Cell Biochem Biophys | 2026 | 42599649 | PubTator, text mining | PubMed |
| The dual pathological roles and targeted therapy of PGE2: from receptor signaling networks to disease microenvironment modulation. | Front Pharmacol | 2026 | 42528719 | PubTator, text mining | PubMed |
| The update of prostaglandin E2 receptor subtype 4 (EP4) in inflammatory diseases. | Genes Dis | 2026 | 42494643 | PubTator, text mining | PubMed |
Retraction notice to "Identification of autophagy-related biomarker and analysis of immune infiltrates in diabetic nephropathy: PTGER1 protein macromolecular structure and function" [Int. J. Biol. Macromol. 311 (2025) 144063]. | Int J Biol Macromol | 2026 | 42481317 | PubTator, text mining | PubMed |
| Leishmanicidal Potential of Eugenia pyriformis Cambess. (Myrtaceae) Leaf Extracts: Metabolomics and Mechanism of Action. | Chem Biodivers | 2026 | 42407029 | PubTator, text mining | PubMed |
| Cardiovascular safety profile of prostaglandin E and prostacyclin analogues: Clinical reports and ex vivo studies on human coronary arteries. | Prostaglandins Leukot Essent Fatty Acids | 2026 | 42385560 | PubTator, text mining | PubMed |
| Redox-sensitive GPCR signaling drives Gq-dependent Ca2+ mobilization and cytokine production in human bronchial epithelial cells. | Am J Physiol Cell Physiol | 2026 | 42314770 | PubTator, text mining | PubMed |
| The bromodomain protein Bdf3 is sufficient to activate expression of a procyclin gene in bloodstream stage African trypanosomes. | mSphere | 2026 | 42223268 | PubTator, text mining | PubMed |
| Screening Epitopes Through Comparative Analysis of Children and Mice Immune Responses to Pertussis Toxin Subunits (S1-S5) Induced by Whole-Cell Pertussis Vaccination. | Vaccines (Basel) | 2026 | 42188785 | PubTator, text mining | PubMed |
1 to 10 of 2,455
See all 2,455 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5731
GET https://conductscience.org/api/genes/v1/5731/patents?page=2