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Gene · 57332

CBX8: chromobox 8

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CBX8: chromobox 8. Genes, record 57332. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/57332

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Gene

Symbol
CBX8
HGNC
Name
chromobox 8
HGNC
NCBI Gene ID
57332
NCBI Gene
HGNC ID
HGNC:15962
HGNC
Ensembl
ENSG00000141570
NCBI Gene
Aliases
HPC3, PC3, RC1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9HC52Chromobox protein homolog 83893Ensembl, GeneID, HGNC

Source UniProt

Patents18

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-192706Q9HC52Espacenet
EP 4640849 A22025-10-29335Q9HC52Espacenet
EP 4641201 A22025-10-292293Q9HC52Espacenet
JP 2025519096 A2025-06-24335Q9HC52Espacenet
JP 2025517969 A2025-06-122293Q9HC52Espacenet
JP 2025517970 A2025-06-122706Q9HC52Espacenet
US 11446398 B22022-09-2015229Q9HC52Espacenet
JP 2022524081 A2022-04-27118200Q9HC52Espacenet
US 11078247 B22021-08-031647Q9HC52Espacenet
JP 2019033757 A2019-03-0722651Q9HC52Espacenet

1 to 10 of 18

See all 18 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,511

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCBX8 papersNewest fiscal year
P30CA008748Cancer Center Support Grant92025
P01AI100148Developing Immunogens to Elicit Broadly Neutralizing anti-HIV-1 Antibodies52025
P30CA016672Cancer Center Support Grant52025
P30CA023168Cancer Center Support Grant52025
P30CA014236Cancer Center Support Grant (CCSG)32025
P30CA016086Cancer Center Support Grant32025
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant32025
P30CA044579University of Virginia Cancer Center Support Grant32025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center32025
P30CA076292Moffitt Cancer Center Support Grant32025

1 to 10 of 1,511Source NIH's project files

See all 1,511 nih grants

Papers1,904

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Body-composition phenotype axes provide additional explanatory information for cardiorespiratory fitness and liver-related metabolic risk within BMI strata.Front Nutr202642741279PubTator, text miningPubMed
Targeting the PRMT5-CBX8 axis overcomes dual barriers of CD8⁺ T cell exclusion and tumor stemness for sensitizing TNBC to anti-PD-1 therapy.Oncogene202642736388PubTator, text miningPubMed
Antioxidant dietary patterns mitigate pain and raise psychological wellbeing in ovarian endometrioma: surgical status shapes associations.Front Nutr202642656205PubTator, text miningPubMed
WDR72 Promotes Neuroblastoma Stemness and Progression by Sequestering TRIM31-Mediated Degradation of CBX8.Adv Sci (Weinh)202642531598PubTator, text miningPubMed
Developmental Brain Network Trajectories Differentiate Resilience and Vulnerability to Psychosis in 22q11.2 Deletion Syndrome.Biol Psychiatry Glob Open Sci202642502641PubTator, text miningPubMed
ZNF695 Promotes Colorectal Cancer Progression Through Transcriptional Activation of CBX8 and Subsequent Wnt/β-Catenin Signaling Activation.Mol Carcinog202642472386PubTator, text miningPubMed
Evaluating mining-related metal inputs in reservoir sediments using chemometrics and Monte Carlo simulation: A complementary environmental forensic perspective.Environ Res202642288277PubTator, text miningPubMed
The MLLT3 YEATS domain binds histone marks (H3K9/18/27ac/cr) and ncRNA (7SK), linking transcription and RNA signaling to regulate hematopoiesis.Cell Rep202642268713PubTator, text miningPubMed
Mechanism of AF9 (MLLT3)-Partner Dissociation in Mixed-Lineage Leukemia-Rearranged Leukemia.JACS Au202642063817PubTator, text miningPubMed
CBX8 suppresses autophagy-dependent senescence in colorectal cancer by modulating the mTOR signaling pathway.Int J Biol Sci202641943835PubTator, text miningPubMed

1 to 10 of 1,904

See all 1,904 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/57332

GET https://conductscience.org/api/genes/v1/57332/patents