Gene · 57332
CBX8: chromobox 8
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CBX8: chromobox 8. Genes, record 57332. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/57332
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9HC52 | Chromobox protein homolog 8 | 389 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents18
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 2706 | Q9HC52 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 335 | Q9HC52 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 2293 | Q9HC52 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 335 | Q9HC52 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 2293 | Q9HC52 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2706 | Q9HC52 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 15229 | Q9HC52 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 118200 | Q9HC52 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 1647 | Q9HC52 | Espacenet |
| JP 2019033757 A | 2019-03-07 | 22651 | Q9HC52 | Espacenet |
1 to 10 of 18
See all 18 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,511
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CBX8 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 9 | 2025 |
| P01AI100148 | Developing Immunogens to Elicit Broadly Neutralizing anti-HIV-1 Antibodies | 5 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| P30CA023168 | Cancer Center Support Grant | 5 | 2025 |
| P30CA014236 | Cancer Center Support Grant (CCSG) | 3 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 3 | 2025 |
| P30CA023074 | University of Arizona Cancer Center - Cancer Center Support Grant | 3 | 2025 |
| P30CA044579 | University of Virginia Cancer Center Support Grant | 3 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 3 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 1,511Source NIH's project files
See all 1,511 nih grantsPapers1,904
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Body-composition phenotype axes provide additional explanatory information for cardiorespiratory fitness and liver-related metabolic risk within BMI strata. | Front Nutr | 2026 | 42741279 | PubTator, text mining | PubMed |
| Targeting the PRMT5-CBX8 axis overcomes dual barriers of CD8⁺ T cell exclusion and tumor stemness for sensitizing TNBC to anti-PD-1 therapy. | Oncogene | 2026 | 42736388 | PubTator, text mining | PubMed |
| Antioxidant dietary patterns mitigate pain and raise psychological wellbeing in ovarian endometrioma: surgical status shapes associations. | Front Nutr | 2026 | 42656205 | PubTator, text mining | PubMed |
| WDR72 Promotes Neuroblastoma Stemness and Progression by Sequestering TRIM31-Mediated Degradation of CBX8. | Adv Sci (Weinh) | 2026 | 42531598 | PubTator, text mining | PubMed |
| Developmental Brain Network Trajectories Differentiate Resilience and Vulnerability to Psychosis in 22q11.2 Deletion Syndrome. | Biol Psychiatry Glob Open Sci | 2026 | 42502641 | PubTator, text mining | PubMed |
| ZNF695 Promotes Colorectal Cancer Progression Through Transcriptional Activation of CBX8 and Subsequent Wnt/β-Catenin Signaling Activation. | Mol Carcinog | 2026 | 42472386 | PubTator, text mining | PubMed |
| Evaluating mining-related metal inputs in reservoir sediments using chemometrics and Monte Carlo simulation: A complementary environmental forensic perspective. | Environ Res | 2026 | 42288277 | PubTator, text mining | PubMed |
| The MLLT3 YEATS domain binds histone marks (H3K9/18/27ac/cr) and ncRNA (7SK), linking transcription and RNA signaling to regulate hematopoiesis. | Cell Rep | 2026 | 42268713 | PubTator, text mining | PubMed |
| Mechanism of AF9 (MLLT3)-Partner Dissociation in Mixed-Lineage Leukemia-Rearranged Leukemia. | JACS Au | 2026 | 42063817 | PubTator, text mining | PubMed |
| CBX8 suppresses autophagy-dependent senescence in colorectal cancer by modulating the mTOR signaling pathway. | Int J Biol Sci | 2026 | 41943835 | PubTator, text mining | PubMed |
1 to 10 of 1,904
See all 1,904 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/57332
GET https://conductscience.org/api/genes/v1/57332/patents