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Gene · 57338

JPH3: junctophilin 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. JPH3: junctophilin 3. Genes, record 57338. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/57338

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Gene

Symbol
JPH3
HGNC
Name
junctophilin 3
HGNC
NCBI Gene ID
57338
NCBI Gene
HGNC ID
HGNC:14203
HGNC
Ensembl
ENSG00000154118
NCBI Gene
Aliases
CAGL237, HDL2, JP-3, JP3, TNRC22
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8WXH2Junctophilin-37480Ensembl, GeneID, HGNC

Source UniProt

Patents18

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1450511Q8WXH2Espacenet
EP 4641201 A22025-10-292792Q8WXH2Espacenet
JP 2025529142 A2025-09-042182Q8WXH2Espacenet
US 12371689 B22025-07-292182Q8WXH2Espacenet
JP 2025517969 A2025-06-122792Q8WXH2Espacenet
JP 2025032204 A2025-03-1130180Q8WXH2Espacenet
EP 4461818 A22024-11-1330180Q8WXH2Espacenet
JP 2023058610 A2023-04-2530180Q8WXH2Espacenet
US 11446398 B22022-09-2042393Q8WXH2Espacenet
US 11400116 B22022-08-024690Q8WXH2Espacenet

1 to 10 of 18

See all 18 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,098

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleJPH3 papersNewest fiscal year
P30DK017047Diabetes Research Center202025
P30DK035816Nutrition Obesity Research Center112025
P01HL116263HDL Function in Human Disease72025
P01HL128203Multi-disciplinary Approaches to HDL Structure, Assembly, and Functional Heterogeneity52025
R01NS098819Molecular effects of metformin, PKR and TBI on C9orf72 ALS/FTD42025
I01BX000900Effect of SMSr on VLDL metabolism and atherosclerosis32025
P01CA092584Structural Cell Biology of DNA Repair Machines32025
P30CA138313Medical University of South Carolina - Cancer Center Support Grant32025
P30DK040561Boston Area Nutrition Obesity Research Center (NORC)32025
P30DK056341Washington University Nutrition Obesity Research Center32025

1 to 10 of 1,098Source NIH's project files

See all 1,098 nih grants

Papers2,271

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Lipid and High-Density Lipoprotein (HDL) Subfraction Changes in Premenopausal and Postmenopausal Women With Breast Cancer Receiving Hormonal Therapy.Cureus202642292016PubTator, text miningPubMed
Integrated 2D-3D Proteomic Profiling Identifies MLK4 as a Microenvironment-Responsive Regulator of Chemotherapeutic Resistance in Human Glioblastoma Cells.Biol Cell202642068033PubTator, text miningPubMed
Dissociation Between Cholesteryl Ester Transfer Protein Mass and Activity in Coronary Artery Disease Patients with Elevated High-Density Lipoprotein Cholesterol: Implications for High-Density Lipoprotein Function and Residual Cardiovascular Risk.
Anatol J Cardiol202642037376PubTator, text miningPubMed
Unraveling the genetic architecture of non-Huntington chorea: a biobank-scale study of rare variants and repeat expansions.NPJ Genom Med202641957010PubTator, text miningPubMed
JPH3 Facilitates Cisplatin Resistance in Anaplastic Thyroid Cancer via Activation of the JAK-STAT Signaling Pathway.Cancer Med202641862190PubTator, text miningPubMed
The effect of cold ischemia time on hypoxia, EMT, and apoptosis pathways in normal colon mucosa.PLoS One202641860925PubTator, text miningPubMed
A narrative review of impacts of apolipoproteins on atherosclerotic coronary plaques.NPJ Cardiovasc Health202641775966PubTator, text miningPubMed
Effects of Sodium Glucose Cotransporter 2 (SGLT2) Inhibitors on Lipid Profiles in Type 2 Diabetes: A Systematic Review.Cureus202641773139PubTator, text miningPubMed
Effects of Phenolic Acids-Rich Brussels Chicory on Fasting and Postprandial Vascular Function, HDL Functions, and Subclass Profiles in Healthy Overweight Men: A Randomized, Controlled, Single-Blind, Three-Way Crossover Study.
Mol Nutr Food Res202641761871PubTator, text miningPubMed
Detection of germline variants in human population chronically exposed to high level natural background radiation in Kerala coast.Genes Environ202641761368PubTator, text miningPubMed

1 to 10 of 2,271

See all 2,271 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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