Gene · 5737
PTGFR: prostaglandin F receptor
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PTGFR: prostaglandin F receptor. Genes, record 5737. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5737
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P43088 | Prostaglandin F2-alpha receptor | 359 | 8 | Ensembl, GeneID, HGNC |
Source UniProt
Patents61
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 59419 | P43088 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 59420 | P43088 | Espacenet |
| EP 4667578 A2 | 2025-12-24 | 213 | P43088 | Espacenet |
| EP 4667578 A2 | 2025-12-24 | 214 | P43088 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 8833 | P43088 | Espacenet |
| JP 2025131621 A | 2025-09-09 | 213 | P43088 | Espacenet |
| JP 2025131621 A | 2025-09-09 | 214 | P43088 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 3624 | P43088 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 3624 | P43088 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 8833 | P43088 | Espacenet |
1 to 10 of 61
See all 61 patentsDrugs11
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action | Source |
|---|---|---|---|---|
| AL-12182 | CHEMBL184999 | Prostanoid FP receptor agonist | AGONIST | ChEMBL |
| BIMATOPROST | CHEMBL1200963 | Prostanoid FP receptor agonist | AGONIST | ChEMBL |
| CARBOPROST | CHEMBL1237122 | Prostanoid FP receptor agonist | AGONIST | ChEMBL |
| CARBOPROST TROMETHAMINE | CHEMBL1237105 | Prostanoid FP receptor agonist | AGONIST | ChEMBL |
| DINOPROST | CHEMBL815 | Prostanoid FP receptor agonist | AGONIST | ChEMBL |
| DINOPROST TROMETHAMINE | CHEMBL1200896 | Prostanoid FP receptor agonist | AGONIST | ChEMBL |
| LATANOPROST | CHEMBL1051 | Prostanoid FP receptor agonist | AGONIST | ChEMBL |
| LATANOPROSTENE BUNOD | CHEMBL2364612 | Prostanoid FP receptor agonist | AGONIST | ChEMBL |
| SEPETAPROST | CHEMBL4297633 | Prostanoid FP receptor agonist | AGONIST | ChEMBL |
| TAFLUPROST | CHEMBL1963683 | Prostanoid FP receptor agonist | AGONIST | ChEMBL |
1 to 10 of 11
See all 11 drugsTrials425
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT07495852 | TRAVOPROST | PHASE3 | ClinicalTrials.gov | |
| NCT07435012 | LATANOPROST | PHASE3 | ClinicalTrials.gov | |
| NCT07400926 | TRAVOPROST | ClinicalTrials.gov | ||
| NCT07325240 | LATANOPROST | PHASE4 | ClinicalTrials.gov | |
| NCT07228221 | TRAVOPROST | PHASE4 | ClinicalTrials.gov | |
| NCT07218796 | BIMATOPROST | PHASE3 | ClinicalTrials.gov | |
| NCT07218783 | BIMATOPROST | PHASE3 | ClinicalTrials.gov | |
| NCT07154797 | BIMATOPROST | ClinicalTrials.gov | ||
| NCT07082816 | LATANOPROST | PHASE3 | ClinicalTrials.gov | |
| NCT07075718 | TRAVOPROST | PHASE2/PHASE3 | ClinicalTrials.gov |
1 to 10 of 425
See all 425 trialsNIH grants557
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PTGFR papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
| ZIAHD002400 | The Role Of Subclinical Infection And Cytokines In Preterm Parturition | 3 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 2 | 2025 |
| P30ES013508 | Center of Excellence in Environmental Toxicology | 2 | 2025 |
| P30EY008126 | Core Grant in Vision Research | 2 | 2025 |
| P30EY014801 | Miami Center for Vision Research | 2 | 2025 |
| P51OD011092 | Support for National Primate Research Center | 2 | 2025 |
| U01CA200462 | MD Anderson Cancer Center EDRN- Clinical Validation Center for Early Detection of Ovarian Cancer with a multiple marker algorithm | 2 | 2025 |
| U54GM104942 | West Virginia Clinical and Translational Science Institute: A Statewide Organization Building Research Excellence and Engaging Communities to Improve Health | 2 | 2025 |
| I50RX003002 | Center for the Prevention and Treatment of Visual Loss | 1 | 2025 |
1 to 10 of 557Source NIH's project files
See all 557 nih grantsPapers1,138
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Establishment of a Predictive Model for Mortality in Sepsis Patients Using WGCNA and Machine Learning Algorithms. | J Inflamm Res | 2026 | 42605381 | PubTator, text mining | PubMed |
| Topical latanoprost acid for female androgenetic alopecia: a pilot proof-of-concept trial with mechanistic evidence of prostaglandin F2α receptor activation. | Pharmacol Rep | 2026 | 42430069 | PubTator, text mining | PubMed |
| An environmentally relevant phthalate mixture impairs ovulatory prostaglandin and progesterone receptor pathways in human granulosa cells in vitro. | Environ Int | 2026 | 41807910 | PubTator, text mining | PubMed |
| Regulatory roles of bioactive lipids in vascular homeostasis and remodeling. | Med Rev (2021) | 2026 | 41783891 | PubTator, text mining | PubMed |
| Use of genetics in the prediction of success in male pattern hair loss therapy and mechanistic studies. | Front Pharmacol | 2026 | 41769701 | PubTator, text mining | PubMed |
| Structural and Biophysical Analyses of Human Prostamide/Prostaglandin F Synthase with Two Active Form-Mimicking Mutations. | Biomolecules | 2026 | 41750332 | PubTator, text mining | PubMed |
| Bioengineering of extracellular vesicles with scaffold proteins for drug delivery. | J Nanobiotechnology | 2026 | 41680844 | PubTator, text mining | PubMed |
| Unveiling novel potential drug targets for lung cancer through Mendelian randomization analysis. | Sci Rep | 2025 | 41436647 | PubTator, text mining | PubMed |
| Novel N‑Arylquinoline-4-carboxamide Derivatives as Prostaglandin F Receptor Antagonists. | ACS Med Chem Lett | 2025 | 41257019 | PubTator, text mining | PubMed |
| Glaucoma diagnosis and treatment in the era of precision medicine. | Pharmacogenomics | 2025 | 41147667 | PubTator, text mining | PubMed |
1 to 10 of 1,138
See all 1,138 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5737
GET https://conductscience.org/api/genes/v1/5737/patents?page=2