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Gene · 5737

PTGFR: prostaglandin F receptor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PTGFR: prostaglandin F receptor. Genes, record 5737. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5737

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Gene

Symbol
PTGFR
HGNC
Name
prostaglandin F receptor
HGNC
NCBI Gene ID
5737
NCBI Gene
HGNC ID
HGNC:9600
HGNC
Ensembl
ENSG00000122420
NCBI Gene
Aliases
FP
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P43088Prostaglandin F2-alpha receptor3598Ensembl, GeneID, HGNC

Source UniProt

Patents61

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1459419P43088Espacenet
JP 2026004568 A2026-01-1459420P43088Espacenet
EP 4667578 A22025-12-24213P43088Espacenet
EP 4667578 A22025-12-24214P43088Espacenet
EP 4650780 A22025-11-198833P43088Espacenet
JP 2025131621 A2025-09-09213P43088Espacenet
JP 2025131621 A2025-09-09214P43088Espacenet
JP 2025529142 A2025-09-043624P43088Espacenet
US 12371689 B22025-07-293624P43088Espacenet
JP 2025517970 A2025-06-128833P43088Espacenet

1 to 10 of 61

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Drugs11

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
AL-12182CHEMBL184999Prostanoid FP receptor agonistAGONISTChEMBL
BIMATOPROSTCHEMBL1200963Prostanoid FP receptor agonistAGONISTChEMBL
CARBOPROSTCHEMBL1237122Prostanoid FP receptor agonistAGONISTChEMBL
CARBOPROST TROMETHAMINECHEMBL1237105Prostanoid FP receptor agonistAGONISTChEMBL
DINOPROSTCHEMBL815Prostanoid FP receptor agonistAGONISTChEMBL
DINOPROST TROMETHAMINECHEMBL1200896Prostanoid FP receptor agonistAGONISTChEMBL
LATANOPROSTCHEMBL1051Prostanoid FP receptor agonistAGONISTChEMBL
LATANOPROSTENE BUNODCHEMBL2364612Prostanoid FP receptor agonistAGONISTChEMBL
SEPETAPROSTCHEMBL4297633Prostanoid FP receptor agonistAGONISTChEMBL
TAFLUPROSTCHEMBL1963683Prostanoid FP receptor agonistAGONISTChEMBL

1 to 10 of 11

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Trials425

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07495852TRAVOPROSTPHASE3ClinicalTrials.gov
NCT07435012LATANOPROSTPHASE3ClinicalTrials.gov
NCT07400926TRAVOPROSTClinicalTrials.gov
NCT07325240LATANOPROSTPHASE4ClinicalTrials.gov
NCT07228221TRAVOPROSTPHASE4ClinicalTrials.gov
NCT07218796BIMATOPROSTPHASE3ClinicalTrials.gov
NCT07218783BIMATOPROSTPHASE3ClinicalTrials.gov
NCT07154797BIMATOPROSTClinicalTrials.gov
NCT07082816LATANOPROSTPHASE3ClinicalTrials.gov
NCT07075718TRAVOPROSTPHASE2/PHASE3ClinicalTrials.gov

1 to 10 of 425

See all 425 trials

NIH grants557

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePTGFR papersNewest fiscal year
P30CA016672Cancer Center Support Grant32025
ZIAHD002400The Role Of Subclinical Infection And Cytokines In Preterm Parturition32025
P30CA068485Cancer Center Support Grant22025
P30ES013508Center of Excellence in Environmental Toxicology22025
P30EY008126Core Grant in Vision Research22025
P30EY014801Miami Center for Vision Research22025
P51OD011092Support for National Primate Research Center22025
U01CA200462MD Anderson Cancer Center EDRN- Clinical Validation Center for Early Detection of Ovarian Cancer with a multiple marker algorithm22025
U54GM104942West Virginia Clinical and Translational Science Institute: A Statewide Organization Building Research Excellence and Engaging Communities to Improve Health22025
I50RX003002Center for the Prevention and Treatment of Visual Loss12025

1 to 10 of 557Source NIH's project files

See all 557 nih grants

Papers1,138

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Establishment of a Predictive Model for Mortality in Sepsis Patients Using WGCNA and Machine Learning Algorithms.J Inflamm Res202642605381PubTator, text miningPubMed
Topical latanoprost acid for female androgenetic alopecia: a pilot proof-of-concept trial with mechanistic evidence of prostaglandin F2α receptor activation.Pharmacol Rep202642430069PubTator, text miningPubMed
An environmentally relevant phthalate mixture impairs ovulatory prostaglandin and progesterone receptor pathways in human granulosa cells in vitro.Environ Int202641807910PubTator, text miningPubMed
Regulatory roles of bioactive lipids in vascular homeostasis and remodeling.Med Rev (2021)202641783891PubTator, text miningPubMed
Use of genetics in the prediction of success in male pattern hair loss therapy and mechanistic studies.Front Pharmacol202641769701PubTator, text miningPubMed
Structural and Biophysical Analyses of Human Prostamide/Prostaglandin F Synthase with Two Active Form-Mimicking Mutations.Biomolecules202641750332PubTator, text miningPubMed
Bioengineering of extracellular vesicles with scaffold proteins for drug delivery.J Nanobiotechnology202641680844PubTator, text miningPubMed
Unveiling novel potential drug targets for lung cancer through Mendelian randomization analysis.Sci Rep202541436647PubTator, text miningPubMed
Novel N‑Arylquinoline-4-carboxamide Derivatives as Prostaglandin F Receptor Antagonists.ACS Med Chem Lett202541257019PubTator, text miningPubMed
Glaucoma diagnosis and treatment in the era of precision medicine.Pharmacogenomics202541147667PubTator, text miningPubMed

1 to 10 of 1,138

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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