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Gene · 5745

Papers2,698

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Discovery and characterization of potent and efficacious small-molecule parathyroid hormone Receptor-1 (PTH1R) antagonists for the treatment of hypercalcemia.Bioorg Med Chem Lett202742822604PubTator, text miningPubMed
Eiken syndrome presenting as pseudohypoparathyroidism due to PTH1R gene pathogenic variant.JCEM Case Rep202642824313PubTator, text miningPubMed
Statement of Retraction: Convallatoxin suppresses osteosarcoma cell proliferation, migration, invasion, and enhances osteogenic differentiation by downregulating parathyroid hormone receptor 1 (PTHR1) expression and inactivating Wnt/β-catenin pathway.
Bioengineered202642821801PubTator, text miningPubMed
A novel PTH1R missense variant in a patient with early-onset primary hyperparathyroidism.Bone Rep202642751087PubTator, text miningPubMed
Spatial control of parathyroid hormone receptor-1 signaling dictates ligand-specific biological outcomes.Signal Transduct Target Ther202642722652PubTator, text miningPubMed
Structural basis of β-arrestin coupling and transducer selectivity in PAC1R.Acta Pharmacol Sin202642706324PubTator, text miningPubMed
Adynamic Bone Disease in Chronic Kidney Disease: From Parathyroid Hormone Suppression-Driven Remodeling Phenotype to Osteoanabolic Therapy.Am J Nephrol202642671953PubTator, text miningPubMed
Association of EBV EBNA1 C-terminal variations with severity of Invasive ductal carcinoma.Mol Biol Rep202642667440PubTator, text miningPubMed
De-Nterm-ining GLP1R signaling bias.Trends Pharmacol Sci202642660721PubTator, text miningPubMed
Skeletal dysplasias of the parathyroid hormone signaling cascade: radiological manifestations and molecular mechanisms.Pediatr Radiol202642631736PubTator, text miningPubMed
Case report: compound heterozygous PTH1R variant(s) in a patient with inactivating PTH/PTHrP signalling disorder type 1 (iPPSD1).J Pediatr Endocrinol Metab202642616834PubTator, text miningPubMed
The impact of parathyroid hormone replacement with palopegteriparatide on synthesis of 1,25-dihydroxy vitamin D in hypoparathyroidism.Expert Rev Clin Pharmacol202642605157PubTator, text miningPubMed
Therapeutic and Predicted Significance of PKLR in Patients With Cholangiocarcinoma.Cancer Rep (Hoboken)202642599115PubTator, text miningPubMed
Pharmacological effects of PTH1R agonists on jaw bone fracture, periodontitis, orthodontic treatment and MRONJ: a view from dosing regimen settings.J Oral Biosci202642503281PubTator, text miningPubMed
Threonine Phosphorylation Is a Bioreversible Surrogate of Proline Hydroxylation in a Collagen Triple Helix.J Am Chem Soc202642424232PubTator, text miningPubMed
The PTHR1/PKA/CREB1 axis promotes osteosarcoma progression by activating the PVT1/miR-590-3p/AXIN2 ceRNA network to induce epithelial-mesenchymal transition.Biol Direct202642374479PubTator, text miningPubMed
Regulation of cAMP levels in osteocytes by mechano-sensitive focal adhesion kinase and phosphodiesterase 8A.iScience202642231949PubTator, text miningPubMed
Multivalent antibody-based conjugates as new tools for tailored modulation of G protein-coupled receptors.Br J Pharmacol202642225334PubTator, text miningPubMed
[PTHrP-producing diffuse large B-cell lymphoma presenting with hypercalcemia at diagnosis].Rinsho Ketsueki202642128862PubTator, text miningPubMed
Spatiotemporal complexity and druggability of PTH1R: insights from small molecules and peptides.Mol Cell Endocrinol202642119631PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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