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Gene · 57492

ARID1B: AT-rich interaction domain 1B

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ARID1B: AT-rich interaction domain 1B. Genes, record 57492. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/57492

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Gene

Symbol
ARID1B
HGNC
Name
AT-rich interaction domain 1B
HGNC
NCBI Gene ID
57492
NCBI Gene
HGNC ID
HGNC:18040
HGNC
Ensembl
ENSG00000049618
NCBI Gene
Aliases
6A3-5, BAF250B, BAF250b, BRIGHT, CSS1, DAN15, ELD/OSA1, KIAA1235, MRD12, OSA2, P250R, SMARCF2, p250R
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8NFD5AT-rich interactive domain-containing protein 1B2,3192Ensembl, GeneID, HGNC

Source UniProt

Patents0

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

None in this release.

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,129

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleARID1B papersNewest fiscal year
P30CA008748Cancer Center Support Grant712025
P30CA016672Cancer Center Support Grant262025
R01MH101221Rare Mutations and Autism Spectrum Disorders262025
P30CA010815Consolidated Basic Cancer Research Program132025
P30CA021765Cancer Center Support Grant (CCSG)132025
R01CA202919Mechanistic basis and therapeutic strategies for ARID1A mutation in ovarian cancer132025
R01CA113794The function of Snf5 (SMARCB1), an epigenetic tumor suppressor112025
P30CA006973Regional Oncology Research Center102025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant102025
R01CA172152Role of the SWI/SNF complex in tumor suppression102025

1 to 10 of 2,129Source NIH's project files

See all 2,129 nih grants

Papers2,473

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A guide to selecting high-performing antibodies for ARID1B (UniProt ID: Q8NFD5) for use in western blot and immunoprecipitation.F1000Res202642806975PubTator, text miningPubMed
ARID2 Loss Destabilizes PBAF and Drives Colorectal Cancer.Mol Carcinog202642762512PubTator, text miningPubMed
Multiomic Investigation of Shared Genetic Pathways in Paediatric Congenital Heart Disease and Neurodevelopmental Disorders.Hum Mutat202642633081PubTator, text miningPubMed
ARID1B mutations promote immune evasion in acute myeloid leukemia through upregulating VISTA expression.Int Immunopharmacol202642600271PubTator, text miningPubMed
Cryptic small-molecule binding sites in the ARID1B DNA-binding domain.Proc Natl Acad Sci U S A202642585010PubTator, text miningPubMed
Decoding the Complexity of Hepatocellular Carcinoma: Clinical Challenges and Targeting HuR as a Novel Therapeutic Strategy.Livers202642583674PubTator, text miningPubMed
Infantile giant intracranial-extracranial communicating mixed germ cell tumor with ARID1B gene mutation: a case report.Front Oncol202642558373PubTator, text miningPubMed
Genotypic and Phenotypic Profile of 50 Cases With Chromatin Remodeling Complexes-Related Neurological Disorders.CNS Neurosci Ther202642528014PubTator, text miningPubMed
Characterizing ARID1B-related disorders and variants of uncertain significance using DNA methylation.Eur J Hum Genet202642527582PubTator, text miningPubMed
[SMARCB1-deficient sinonasal adenocarcinoma: clinicopathological and molecular genetic characteristics of four cases].Zhonghua Bing Li Xue Za Zhi202642379852PubTator, text miningPubMed

1 to 10 of 2,473

See all 2,473 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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