ConductScience.org, home

Library / Genes

MAVS: mitochondrial antiviral signaling protein

1 protein, 43 patents, 0 drugs, 0 trials, 4,347 NIH grants and 7,847 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolMAVSHGNC
Namemitochondrial antiviral signaling proteinHGNC
NCBI Gene ID57506NCBI Gene
HGNC IDHGNC:29233HGNC
EnsemblENSG00000088888NCBI Gene
AliasesCARDIF, Cardif, IPS-1, IPS1, KIAA1271, VISANCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q7Z434Mitochondrial antiviral-signaling protein54011Ensembl, GeneID, HGNCUniProt

Patents 43

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1453656Q7Z434Espacenet
EP 4650780 A22025-11-1913133Q7Z434Espacenet
EP 4641201 A22025-10-2914826Q7Z434Espacenet
JP 2025529142 A2025-09-042561Q7Z434Espacenet
US 12371689 B22025-07-292561Q7Z434Espacenet
JP 2025517969 A2025-06-1214826Q7Z434Espacenet
JP 2025517970 A2025-06-1213133Q7Z434Espacenet
US 11478530 B22022-10-254Q7Z434Espacenet
US 11446398 B22022-09-2051768Q7Z434Espacenet
US 11400116 B22022-08-024714Q7Z434Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4347

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P01CA019014Viral Oncogenesis, Latency, and Replication192,025NIH's project files
P30CA008748Cancer Center Support Grant182,025NIH's project files
P30DK034854Integrated Epithelial and Muscosal Biology172,025NIH's project files
P30CA016086Cancer Center Support Grant162,025NIH's project files
R01AI124346Innate immune signaling and stress response132,025NIH's project files
R01AI107301Genetic Viral and Host Adaptations to Breach Species Barriers of HCV122,025NIH's project files
R37AI101935Inflammatory Caspases in Innate Immunity and Inflammation122,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award122,025NIH's project files
P30AI073961Miami Center for AIDS Research92,025NIH's project files
P51OD011132Emory National Primate Research Center92,025NIH's project files

Papers 7847

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824253PubTator, text miningPubMed
42822072PubTator, text miningPubMed
42808786PubTator, text miningPubMed
42801537PubTator, text miningPubMed
42800308PubTator, text miningPubMed
42796675PubTator, text miningPubMed
42788674PubTator, text miningPubMed
42782124PubTator, text miningPubMed
42781243PubTator, text miningPubMed
42749230PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license