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MIB1: MIB E3 ubiquitin protein ligase 1

1 protein, 18 patents, 0 drugs, 0 trials, 2,208 NIH grants and 11,492 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolMIB1HGNC
NameMIB E3 ubiquitin protein ligase 1HGNC
NCBI Gene ID57534NCBI Gene
HGNC IDHGNC:21086HGNC
EnsemblENSG00000101752NCBI Gene
AliasesDIP-1, DIP1, KIAA1323, LVNC7, MIB, ZZANK2, ZZZ6NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q86YT6E3 ubiquitin-protein ligase MIB11,0066Ensembl, GeneID, HGNCUniProt

Patents 18

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-191913Q86YT6Espacenet
EP 4641201 A22025-10-291500Q86YT6Espacenet
JP 2025517969 A2025-06-121500Q86YT6Espacenet
JP 2025517970 A2025-06-121913Q86YT6Espacenet
US 11446398 B22022-09-2051639Q86YT6Espacenet
JP 2022524081 A2022-04-27154610Q86YT6Espacenet
US 11078247 B22021-08-036804Q86YT6Espacenet
JP 2017121240 A2017-07-1351830Q86YT6Espacenet
JP 2015518704 A2015-07-0651830Q86YT6Espacenet
US 8586006 B22013-11-1920377Q86YT6Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2208

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant742,025NIH's project files
P30CA016672Cancer Center Support Grant482,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant202,025NIH's project files
P30CA006973Regional Oncology Research Center182,025NIH's project files
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant162,025NIH's project files
P50CA097257Brain Tumor SPORE Grant162,025NIH's project files
P50CA116201Mayo Clinic Breast Cancer SPORE122,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase112,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award112,025NIH's project files
P30CA016087Cancer Center Support Grant102,025NIH's project files

Papers 11492

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42779918PubTator, text miningPubMed
42764320PubTator, text miningPubMed
42750818PubTator, text miningPubMed
42709160PubTator, text miningPubMed
42706558PubTator, text miningPubMed
42637882PubTator, text miningPubMed
42559314PubTator, text miningPubMed
42535165PubTator, text miningPubMed
42525816PubTator, text miningPubMed
42485805PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license