Gene · 5754
PTK7: protein tyrosine kinase 7 (inactive)
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PTK7: protein tyrosine kinase 7 (inactive). Genes, record 5754. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5754
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q13308 | Inactive tyrosine-protein kinase 7 | 1,070 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents130
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026509932 A | 2026-03-25 | 75 | Q13308 | Espacenet |
| EP 4683664 A1 | 2026-01-28 | 75 | Q13308 | Espacenet |
| US 12534529 B1 | 2026-01-27 | 198 | Q13308 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 60440 | Q13308 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 767 | Q13308 | Espacenet |
| KR 1020250162887 A | 2025-11-19 | 75 | Q13308 | Espacenet |
| JP 2025168320 A | 2025-11-07 | 1 | Q13308 | Espacenet |
| WO 2025231037 A1 | 2025-11-06 | 198 | Q13308 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 543 | Q13308 | Espacenet |
| WO 2025222052 A2 | 2025-10-23 | 198 | Q13308 | Espacenet |
1 to 10 of 130
See all 130 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants842
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PTK7 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| R35GM122485 | Understanding Signaling by Non-Canonical Receptor Tyrosine Kinases | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
| P30CA023074 | University of Arizona Cancer Center - Cancer Center Support Grant | 3 | 2025 |
| K12CA090628 | Paul Calabresi Program in Clinical/Translational Research at Mayo Clinic | 2 | 2025 |
| P20GM103443 | SD INBRE Administrative Supplement Extension | 2 | 2025 |
| P30CA014520 | UW Comprehensive Cancer Center Support | 2 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 2 | 2025 |
| P30CA016087 | Cancer Center Support Grant | 2 | 2025 |
| P30CA030199 | Cancer Center Support Grant (CCSG) | 2 | 2025 |
1 to 10 of 842Source NIH's project files
See all 842 nih grantsPapers1,606
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A 177Lu-Labeled Circular Bivalent Aptamer for PTK7-Targeting Radionuclide Therapy in Ovarian Cancer and Orthotopic Hepatoblastoma. | J Med Chem | 2026 | 42720498 | PubTator, text mining | PubMed |
| Identification of Glioblastoma Cell Surface Proteins and Assessment of Their Expression Across Patient-Derived Stem-Like Cell Cultures. | J Proteome Res | 2026 | 42695909 | PubTator, text mining | PubMed |
| Targeting Adaptive and Innate Immune Responses with Covalent Aptamers. | J Am Chem Soc | 2026 | 42619145 | PubTator, text mining | PubMed |
| The cell surface proteome of malignant peripheral nerve sheath tumors reveals therapeutic targets. | Neurooncol Adv | 2026 | 42598732 | PubTator, text mining | PubMed |
| Population Pharmacokinetics and Exposure-Response Analyses to Support Cofetuzumab Pelidotin (ABBV-647) Dose Optimization in Non-Small Cell Lung Cancer Patients. | Clin Pharmacol Ther | 2026 | 42596608 | PubTator, text mining | PubMed |
| Harnessing Synergistic Enthalpy-Entropy Regulation: An I-Motif-Based Modulating Design for Programming Stimulus-Responsive DNA Switches. | Angew Chem Int Ed Engl | 2026 | 42578610 | PubTator, text mining | PubMed |
| Circular Bivalent Aptamer Chimeras Leveraging LDLR-Mediated Lysosomal Shuttling for Targeted Protein Degradation. | J Med Chem | 2026 | 42449215 | PubTator, text mining | PubMed |
| MFAP2 secreted by TGF-β1-induced cancer-associated fibroblast cells promotes gastric cancer peritoneal metastasis through Src-STAT3-PTK7 axis. | Cell Death Discov | 2026 | 42420251 | PubTator, text mining | PubMed |
| Multi-omics investigation into the role of PTK7 as a driver of liver fibrosis. | Zhong Nan Da Xue Xue Bao Yi Xue Ban | 2026 | 42394493 | PubTator, text mining | PubMed |
| Late-Stage Carboranylation of Nucleos(t)ides Enabled by Minisci and Pd-Catalyzed B-N Cross-Coupling Reactions: Toward the Synthesis of Carboranyl-Modified Oligonucleotides. | J Am Chem Soc | 2026 | 42329658 | PubTator, text mining | PubMed |
1 to 10 of 1,606
See all 1,606 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5754
GET https://conductscience.org/api/genes/v1/5754/patents?page=2