Gene · 5764
PTN: pleiotrophin
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PTN: pleiotrophin. Genes, record 5764. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5764
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P21246 | Pleiotrophin | 168 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents75
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026090543 A | 2026-06-02 | 325 | P21246 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 58241 | P21246 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 11089 | P21246 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7494 | P21246 | Espacenet |
| WO 2025166063 A1 | 2025-08-07 | 13 | P21246 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 7494 | P21246 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 34223 | P21246 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 11089 | P21246 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 11089 | P21246 | Espacenet |
| KR 1020240176122 A | 2024-12-24 | 8 | P21246 | Espacenet |
1 to 10 of 75
See all 75 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,319
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PTN papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 5 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 5 | 2025 |
| R01HL063199 | The role of beta 2 integrins in macrophage fusion | 4 | 2025 |
| T32CA009686 | Training Grant In Tumor Biology | 4 | 2025 |
| UL1TR001866 | Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success | 4 | 2025 |
| ZIAHD000640 | Regulation Of Childhood Growth | 4 | 2025 |
| K12HD000850 | Pediatric Scientist Development Program | 3 | 2025 |
| P30AG072980 | Arizona Alzheimer's Disease Research Center | 3 | 2025 |
1 to 10 of 1,319Source NIH's project files
See all 1,319 nih grantsPapers2,418
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Airway cell-cell communication in smoking through integration of spatial and single-cell transcriptomics. | Respir Res | 2026 | 42827249 | PubTator, text mining | PubMed |
| The Polycystic Kidney Disease Cyst Transcriptome Defined by Integrating Spatial, Single Nuclear, and Bulk Transcriptomics. | Kidney360 | 2026 | 42804341 | PubTator, text mining | PubMed |
| Plasma and cerebrospinal fluid proteomics reveal distinct patterns of senescence and neuropathology in aging rhesus macaques. | Geroscience | 2026 | 42799938 | PubTator, text mining | PubMed |
| Single-Cell RNA Sequencing of Uterine Tissue from a 70-Day-Old Female Rabbit: Cellular Composition and Fibroblast-Associated Networks. | Genes (Basel) | 2026 | 42793025 | PubTator, text mining | PubMed |
| HMMR+ stromal cells drive human uterine development. | Cell Discov | 2026 | 42706229 | PubTator, text mining | PubMed |
| Integrated Bulk and Single-Cell Transcriptomic Analyses Identify a Five-Gene Signature Associated With Prognosis and the Tumor Microenvironment in Epstein-Barr Virus-Associated Gastric Cancer. | Genet Res (Camb) | 2026 | 42667220 | PubTator, text mining | PubMed |
| Deletion of Pleiotrophin protects against high-fat diet-induced liver metabolic disease, independently of the sexual dimorphism in dietary response. | Mol Biomed | 2026 | 42622926 | PubTator, text mining | PubMed |
| Pleiotrophin regulates presynaptic assembly and function through heparan sulfate-dependent binding to neurexin1. | Cell Rep | 2026 | 42585021 | PubTator, text mining | PubMed |
| ATP13A2 Promotes Endothelial Angiogenic Phenotypes and Is Associated With Poor Prognosis in Liver Hepatocellular Carcinoma. | Mol Carcinog | 2026 | 42574576 | PubTator, text mining | PubMed |
| Evaluation on the significance of miR-338-3p for preterm premature rupture of membranes with histologic chorioamnionitis. | Placenta | 2026 | 42485913 | PubTator, text mining | PubMed |
1 to 10 of 2,418
See all 2,418 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5764
GET https://conductscience.org/api/genes/v1/5764/patents?page=2