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CHD8: chromodomain helicase DNA binding protein 8
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Gene · 57680

Papers1,441

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 1,441

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TitleJournalYearPMIDFound bySource
CHD8-Dependent Chromatin Licensing Sustains Trophoblast Stem Cell Transcriptional Programs.Adv Sci (Weinh)202642801681PubTator, text miningPubMed
CRISPR-Enabled functional genomics in hPSCs-derived neural models for autism spectrum disorder.Metab Brain Dis202642747551PubTator, text miningPubMed
Whole-exome sequencing in individuals with obsessive-compulsive disorder and chronic tic disorders identifies 36 large-effect risk genes.Nat Neurosci202642680906PubTator, text miningPubMed
De novo chromatin remodelling variants in sporadic Chiari 1 malformation.Brain202642640505PubTator, text miningPubMed
An episignature informed systematic analysis to ascertain the clinical significance and consequences of CHD8 missense variants.Eur J Hum Genet202642575949PubTator, text miningPubMed
Advancements in the Understanding of the Genetics of Obsessive-Compulsive Disorder (OCD).Curr Psychiatry Rep202642536245PubTator, text miningPubMed
Genotypic and Phenotypic Profile of 50 Cases With Chromatin Remodeling Complexes-Related Neurological Disorders.CNS Neurosci Ther202642528014PubTator, text miningPubMed
Glial heterogeneity shapes region-specific angiogenesis and neurovascular integrity in the CNS.Sci Adv202642525738PubTator, text miningPubMed
Non-coding RNA dysregulation in autism spectrum disorder: Mechanisms, biomarkers, and therapeutic perspectives.Behav Brain Res202642480870PubTator, text miningPubMed
A Novel Variant of the CHD8 Gene in a Patient with Autism Spectrum Disorder.Genes (Basel)202642353758PubTator, text miningPubMed
Role of CHD chromatin remodelers in heart development.World J Pediatr202642323439PubTator, text miningPubMed
Convergent molecular signatures across eating disorders and obsessive-compulsive disorder in the human brain.Cell Rep202642295976PubTator, text miningPubMed
Adult-onset dystonia associated with CHD8 truncating variants: case series and targeted literature review.Neurogenetics202642237036PubTator, text miningPubMed
Offspring genetic diversity regulates rearing experiences that predict differential susceptibility to Chd8 haploinsufficiency.Commun Biol202642115306PubTator, text miningPubMed
Unraveling the Genetic and Molecular Architecture of Autism Spectrum Disorder: Implications for Clinical Genetics and Genomic Diagnostics.Int J Mol Sci202641977462PubTator, text miningPubMed
Chromatinopathies: clinically overlapping disorders, revealing novel variants and their DNA methylation signatures.Clin Epigenetics202641957673PubTator, text miningPubMed
Maternal opioid use disorder and hepatitis C infection in pregnancy reshape the peripheral immune landscape at term.EBioMedicine202641849830PubTator, text miningPubMed
Next-generation sequencing for DLBCL patients with early failure after frontline R-CHOP chemo-immunotherapy.Front Oncol202641788999PubTator, text miningPubMed
The gut as a central hub for multi-organ crosstalk in aging.Cell Mol Life Sci202641787017PubTator, text miningPubMed
Genetics and Epigenetics of Obsessive-Compulsive Disorder.Genes (Basel)202641751572PubTator, text miningPubMed

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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