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Gene · 57697

FANCM: FA complementation group M

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FANCM: FA complementation group M. Genes, record 57697. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/57697

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Gene

Symbol
FANCM
HGNC
Name
FA complementation group M
HGNC
NCBI Gene ID
57697
NCBI Gene
HGNC ID
HGNC:23168
HGNC
Ensembl
ENSG00000187790
NCBI Gene
Aliases
FAAP250, KIAA1596, POF15, SPGF28
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8IYD8Fanconi anemia group M protein2,0487Ensembl, GeneID, HGNC

Source UniProt

Patents24

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1445853Q8IYD8Espacenet
EP 4641201 A22025-10-292202Q8IYD8Espacenet
JP 2025108697 A2025-07-232Q8IYD8Espacenet
JP 2025517969 A2025-06-122202Q8IYD8Espacenet
US 11976334 B22024-05-07154Q8IYD8Espacenet
US 11446398 B22022-09-2030691Q8IYD8Espacenet
US 11400116 B22022-08-024743Q8IYD8Espacenet
JP 2022534138 A2022-07-2728Q8IYD8Espacenet
JP 2022524081 A2022-04-27133662Q8IYD8Espacenet
KR 1020220012339 A2022-02-032Q8IYD8Espacenet

1 to 10 of 24

See all 24 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,222

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFANCM papersNewest fiscal year
P30CA008748Cancer Center Support Grant252025
P30CA016672Cancer Center Support Grant192025
ZIAAG000741Roles Of DNA Helicases In Pathways Required For Maintenance Of Genomic Stability152025
ZIAAG000746Repair of localized DNA damage152025
P01CA092584Structural Cell Biology of DNA Repair Machines142025
R01HL052725Molecular Pathogenesis of Fanconi Anemia132025
ZIAAG000753Fanconi Anemia Pathway112025
P30CA006973Regional Oncology Research Center102025
R01GM058015Recombinational Mechanisms of DNA Repair102025
ZIAAG000688Investigate the DNA damage response pathway of Fanconi anemia and BRCA proteins102025

1 to 10 of 1,222Source NIH's project files

See all 1,222 nih grants

Papers1,618

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
FANCM restrains structural genome evolution and defines a synthetic lethal dependency in BRCA1 -deficient breast cancer.bioRxiv202642818548PubTator, text miningPubMed
MMEJ repair of breaks at TA repeats maintains ecDNA and cancer fitness.Nature202642778593PubTator, text miningPubMed
FANCM is required for the PAX3::FOXO1-driven oncogenic program in rhabdomyosarcoma.Cell Rep202642715099PubTator, text miningPubMed
Real-World Germline Testing Patterns and Clinical Implications of HRR-Associated Germline Variants in Pancreatic Ductal Adenocarcinoma.Cancers (Basel)202642649894PubTator, text miningPubMed
Disulfide engineering of the FANCM-MHF complex reveals constraints on crosslink design in symmetric oligomers.Protein Sci202642606197PubTator, text miningPubMed
Concordant high-grade glioma in monozygotic twins with germline variants in ATM, FANCC, and FANCM: a case report on combined DNA repair deficiency.Neurooncol Adv202642494996PubTator, text miningPubMed
Germline Multigene Panel Testing in Women With Invasive Lobular Cancer.JAMA Netw Open202642418202PubTator, text miningPubMed
Multi-omics analysis in suspected hereditary breast and ovarian cancer cases reveals novel candidate susceptibility factors.NPJ Breast Cancer202642380125PubTator, text miningPubMed
Genetic Determinants of T-Cell Homeostasis in Critical Illness: An Exploratory Analysis of Immune Gene Variants and TREC Dynamics.J Pers Med202642346589PubTator, text miningPubMed
Germline Predisposition in Pediatric Central Nervous System Tumors: Insights from a Multigene Panel Study.Oncol Res202642232602PubTator, text miningPubMed

1 to 10 of 1,618

See all 1,618 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/57697

GET https://conductscience.org/api/genes/v1/57697/patents?page=2