ConductScience.org, home

Gene · 5771

Papers2,250

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Loop dynamics, allostery, and function in protein tyrosine phosphatases: insights from molecular simulations.Biochem Soc Trans202641562625PubTator, text miningPubMed
New pathogenic PTPN2 variant leading to childhood interstitial lung disease.Thorax202641545210PubTator, text miningPubMed
Novel Protein Tyrosine Phosphatase Nonreceptor Type 2 (PTPN2) Inhibitors for Cancer Treatment.ACS Med Chem Lett202641531968PubTator, text miningPubMed
Mapping of PTP1B, TCPTP, SHP2, and Putative Substrates Reveals Novel Networks in Glomerular Podocytes.J Cell Physiol202641520218PubTator, text miningPubMed
Genotype subtyping approach to identify unnoticed variants in diseases from GWAS data.BioData Min202641519843PubTator, text miningPubMed
Beyond Bulk Metabolomics: Emerging Technologies for Defining Cell-Type Specific Metabolic Pathways in Health and Disease.Biomolecules202541463343PubTator, text miningPubMed
Juvenile-onset Systemic Lupus Erythematosus: Recent Advances in Pathogenesis and Treatment.Curr Rheumatol Rep202541410901PubTator, text miningPubMed
The synergistic pathogenic mechanism of Brucella melitensis M5-90 effector protein BspC in regulating host cell apoptosis, inflammation and oxidative stress.J Med Microbiol202541348573PubTator, text miningPubMed
A powerful bioorthogonal toolbox boosting the development of immune theranostics.Chem Sci202541262343PubTator, text miningPubMed
Targeting Protein Tyrosine Phosphatase Nonreceptor Type 2 with a Novel Inhibitor for the Treatment of Melanoma.J Med Chem202541204903PubTator, text miningPubMed
18p Deletion Syndrome Associated with Type 1 Diabetes and Hashimoto's Thyroiditis: A Case Report on Autoimmune Disorders and Genetic Factors.J Clin Res Pediatr Endocrinol202541194499PubTator, text miningPubMed
Targeting PTPN2 enhances human CAR T cell efficacy and the development of long-term memory in mouse xenograft models.Sci Transl Med202541160667PubTator, text miningPubMed
Uncovering the individual immunotherapeutic roles of PTPN1 and PTPN2 in T cells during dual inhibition.iScience202541142999PubTator, text miningPubMed
Spatiotemporally delivery of Cas9 ribonucleoprotein/DNAzyme logic systems using near-infrared upconversion nanomachine for precise immunotherapy.Acta Pharm Sin B202541132842PubTator, text miningPubMed
Development of Novel PTPN2/1 Inhibitors for the Treatment of Melanoma.J Med Chem202541047545PubTator, text miningPubMed
Impact of genotyping (PTPN2, rs2542151) and (MBOAT7, rs641738) in prediction of fibrosis in Metabolic dysfunction- associated steatotic liver disease' patients.Front Endocrinol (Lausanne)202541019340PubTator, text miningPubMed
PTPN2 acts as a tumor suppressor and therapeutic target in ovarian cancer.Biochem Biophys Res Commun202541005284PubTator, text miningPubMed
PTPN2-KO CAR-T Cells Demonstrate Enhanced Effector Function, CNS Infiltration, and Toxicity in a Non-Human Primate CAR-T Model.bioRxiv202541000930PubTator, text miningPubMed
In vivo CRISPR screens identify modifiers of CAR T cell function in myeloma.Nature202540993381PubTator, text miningPubMed
The type 1 diabetes candidate genes PTPN2 and BACH2 regulate the IFN-α-induced crosstalk between JAK/STAT and MAPKs pathways in human beta cells.EBioMedicine202540966855PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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