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Gene · 57733

GBA3: glucosylceramidase beta 3 (gene/pseudogene)

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GBA3: glucosylceramidase beta 3 (gene/pseudogene). Genes, record 57733. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/57733

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Gene

Symbol
GBA3
HGNC
Name
glucosylceramidase beta 3 (gene/pseudogene)
HGNC
NCBI Gene ID
57733
NCBI Gene
HGNC ID
HGNC:19069
HGNC
Ensembl
ENSG00000249948
NCBI Gene
Aliases
CBG, CBGL1, GLUC, KLRP, KLrP
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9H227Cytosolic beta-glucosidase4695GeneID, HGNC

Source UniProt

Patents10

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2025525334 A2025-08-05371Q9H227Espacenet
WO 2025093745 A12025-05-08175Q9H227Espacenet
WO 2025035031 A12025-02-1352Q9H227Espacenet
JP 2023553904 A2023-12-26968Q9H227Espacenet
US 9512448 B22016-12-0645Q9H227Espacenet
US 8586006 B22013-11-1915625Q9H227Espacenet
US 7740664 B22010-06-22376Q9H227Espacenet
JP 2010500568 A2010-01-0737096Q9H227Espacenet
EP 2057465 A22009-05-1315625Q9H227Espacenet
WO 2008079406 A22008-07-03376Q9H227Espacenet

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,654

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGBA3 papersNewest fiscal year
P30ES013508Center of Excellence in Environmental Toxicology92025
R01AI118891Viral modulation of epitranscriptomic mechanisms92025
R01CA160254Serum Glyco-Markers of Early Hepatocellular Carcinoma Using a Mass Spec Approach82025
P30CA016520Abramson Cancer Center Support Grant72025
P30CA008748Cancer Center Support Grant62025
P30ES017885Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD)62025
T32HG002760Institutional Training in the Genomic Sciences62025
P30CA016086Cancer Center Support Grant52025
R01GM094231COMPUTATIONAL TOOLS FOR MASS SPECTROMETRY-BASED INTERACTOME DATA52025
R01GM130091Quantitative Characterization of Glycopeptide Isomers52025

1 to 10 of 1,654Source NIH's project files

See all 1,654 nih grants

Papers1,720

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Reliable luciferase immunoprecipitation system assays for the detection of porcine reproductive and respiratory syndrome virus antibodies.Vet J202642365893PubTator, text miningPubMed
Specificity profiling of SARS-CoV-2 PLpro using proteome-derived libraries of linear peptides suggests secondary preference for basic motifs.Arch Biochem Biophys202642214738PubTator, text miningPubMed
E50A Mutation Increases the Bioluminescence Activity of picALuc.Biosensors (Basel)202641892059PubTator, text miningPubMed
Recent Developments and Applications of Capillary and Microchip Electrophoresis in Proteomics and Peptidomics (2023-2025).J Sep Sci202641877532PubTator, text miningPubMed
Deciphering the STAT3-PXN positive feedback loop in GBM, IDH-wildtype: transcriptional regulation and inhibition of YB-1 ubiquitination.Cell Death Discov202641872167PubTator, text miningPubMed
A genus-wide interaction atlas across NS4B orthologues identifies a conserved role for UFMylation in orthoflavivirus replication.Nat Commun202641826287PubTator, text miningPubMed
Functional study of two flexible regions of the hepatitis E virus ORF1 replicase.PLoS One202641805850PubTator, text miningPubMed
Application of a novel myristoylproteomics approach identifies GLIPR2 as a key pro-ferroptotic substrate in non-small cell lung cancer.Mater Today Bio202641782991PubTator, text miningPubMed
Prolyl tRNA Synthetase Is Required for Mammarenavirus Multiplication.Viruses202641754545PubTator, text miningPubMed
Super-Resolution Imaging of Nuclear Pore Responses to Mechanical Stress and Energy Depletion.Viruses202641754510PubTator, text miningPubMed

1 to 10 of 1,720

See all 1,720 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/57733

GET https://conductscience.org/api/genes/v1/57733/grants?page=2