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HAMP: hepcidin antimicrobial peptide

1 protein, 358 patents, 1 drug, 1 trial, 3,247 NIH grants and 11,685 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolHAMPHGNC
Namehepcidin antimicrobial peptideHGNC
NCBI Gene ID57817NCBI Gene
HGNC IDHGNC:15598HGNC
EnsemblENSG00000105697NCBI Gene
AliasesHEPC, HFE2B, LEAP-1, LEAP1, PLTRNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P81172Hepcidin846Ensembl, GeneID, HGNCUniProt

Patents 358

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026067851 A2026-04-21136P81172Espacenet
EP 4650780 A22025-11-19549P81172Espacenet
JP 2025169942 A2025-11-141067P81172Espacenet
JP 2025169942 A2025-11-141068P81172Espacenet
JP 2025147176 A2025-10-066370P81172Espacenet
JP 2025147176 A2025-10-066371P81172Espacenet
JP 2025529142 A2025-09-046570P81172Espacenet
JP 2025128207 A2025-09-021P81172Espacenet
US 12371689 B22025-07-296570P81172Espacenet
JP 2025517970 A2025-06-12549P81172Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
LY-2787106CHEMBL2109440Hepcidin inhibitorINHIBITORChEMBL

Trials 1

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT01340976LY-2787106PHASE12018-10-03ClinicalTrials.gov

NIH grants 3247

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01DK095112Regulatory Role of Transferrin in Erythropoiesis and Iron Metabolism272,025NIH's project files
P30CA016672Cancer Center Support Grant182,025NIH's project files
T32GM008721Molecular Biology in Burns and Trauma162,025NIH's project files
P30CA062203Cancer Center Support Grant152,025NIH's project files
P30AG028740University of Florida Older Americans Independence Center (OAIC)142,025NIH's project files
P30DK040561Boston Area Nutrition Obesity Research Center (NORC)142,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award132,025NIH's project files
U54DK110858Center for Iron & Heme Disorders at the University of Utah122,025NIH's project files
ZIAHD001602Regulation Of Intracellular Iron Metabolism122,025NIH's project files
P30DA011041Reinvigorating HIV Prevention and Care for People Who Use Drugs: Accelerating Progress and Sustaining Gains in the Midst of Societal Disruption112,025NIH's project files

Papers 11685

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42822528PubTator, text miningPubMed
42819569PubTator, text miningPubMed
42817965PubTator, text miningPubMed
42814899PubTator, text miningPubMed
42811967PubTator, text miningPubMed
42810570PubTator, text miningPubMed
42800596PubTator, text miningPubMed
42795796PubTator, text miningPubMed
42795377PubTator, text miningPubMed
42795304PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license