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Gene · 57823

SLAMF7: SLAM family member 7

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SLAMF7: SLAM family member 7. Genes, record 57823. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/57823

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Gene

Symbol
SLAMF7
HGNC
Name
SLAM family member 7
HGNC
NCBI Gene ID
57823
NCBI Gene
HGNC ID
HGNC:21394
HGNC
Ensembl
ENSG00000026751
NCBI Gene
Aliases
19A, CD319, CRACC, CS1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9NQ25SLAM family member 73350Ensembl, GeneID, HGNC

Source UniProt

Patents425

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4713439 A12026-03-25248Q9NQ25Espacenet
JP 2026035661 A2026-03-04966Q9NQ25Espacenet
EP 4676978 A12026-01-1423Q9NQ25Espacenet
JP 2026004568 A2026-01-1463686Q9NQ25Espacenet
EP 4650780 A22025-11-198354Q9NQ25Espacenet
JP 2025164866 A2025-10-308Q9NQ25Espacenet
EP 4626924 A12025-10-081Q9NQ25Espacenet
JP 2025147176 A2025-10-0612320Q9NQ25Espacenet
US 12421291 B22025-09-23966Q9NQ25Espacenet
WO 2025191133 A12025-09-1856Q9NQ25Espacenet

1 to 10 of 425

See all 425 patents

Drugs2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
AZINTUXIZUMAB VEDOTINCHEMBL4297859SLAM family member 7 binding agentBINDING AGENTChEMBL
ELOTUZUMABCHEMBL1743010SLAM family member 7 inhibitorINHIBITORChEMBL

Trials65

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06785415ELOTUZUMABPHASE1/PHASE2ClinicalTrials.gov
NCT06518551ELOTUZUMABPHASE1/PHASE2ClinicalTrials.gov
NCT06208150ELOTUZUMABPHASE3ClinicalTrials.gov
NCT06163040ELOTUZUMABClinicalTrials.gov
NCT06158841ELOTUZUMABPHASE3ClinicalTrials.gov
NCT05981209ELOTUZUMABPHASE1ClinicalTrials.gov
NCT05730036ELOTUZUMABPHASE3ClinicalTrials.gov
NCT05675319ELOTUZUMABPHASE3ClinicalTrials.gov
NCT05560399ELOTUZUMABEARLY_PHASE1ClinicalTrials.gov
NCT05170789ELOTUZUMABPHASE2ClinicalTrials.gov

1 to 10 of 65

See all 65 trials

NIH grants1,610

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSLAMF7 papersNewest fiscal year
P30CA008748Cancer Center Support Grant332025
P30CA016672Cancer Center Support Grant252025
P01CA155258Integrative Oncogenomics of Multiple Myeloma202025
U19AI110495An autoimmune center of excellence for the study of IgG4-related disease122025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital102025
P30CA006927Comprehensive Cancer Center Program at Fox Chase92025
P50CA186781Mayo Clinic Multiple Myeloma SPORE92025
P30CA033572Cancer Center Support Grant72025
P30CA091842Cancer Center Support Grant72025
P01CA065493Off-the-Shelf Immune Effector Cells for Hematological Malignancies62025

1 to 10 of 1,610Source NIH's project files

See all 1,610 nih grants

Papers3,217

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Impaired antigen clearance of macrophages associates with heart failure and non-obstructive azoospermia: insights from transcriptomics, in silico knockout, and in vitro validation.Front Immunol202642812170PubTator, text miningPubMed
GPR56 and CD319 identify distinct cytotoxic-associated DP and DN T-cell subsets in early systemic lupus erythematosus.Clin Rheumatol202642745124PubTator, text miningPubMed
Proteomics in the discovery of biomarkers of major complications after allogeneic hematopoietic cell transplantation.Curr Opin Hematol202642673525PubTator, text miningPubMed
Abatacept Reduces CD319+ (SLAMF7) Cytotoxic T Cells and Cytokine Production in Systemic Sclerosis.Arthritis Rheumatol202642621795PubTator, text miningPubMed
CXCR6 and its correlated G protein-coupled receptors and PI3K-AKT pathways were associated with the progression of thyroid cancer.BMC Cancer202642432576PubTator, text miningPubMed
Expression of SLAMF7 on hairy cell leukemia indicates therapy option with SLAMF7-antibody Elotuzumab.Leuk Res Rep202642367242PubTator, text miningPubMed
Harnessing CAR-NK cells against multiple myeloma: current landscape and future directions.Mol Biol Rep202642240912PubTator, text miningPubMed
RNA binding protein YWHAZ mediates specific mRNA translation and regulates cell proliferation and apoptosis in diabetic foot ulcer.Front Med (Lausanne)202642180716PubTator, text miningPubMed
Elotuzumab enhances the anti-tumor activity of Vγ9Vδ2 T cells against primary effusion lymphoma.Eur J Pharmacol202642081990PubTator, text miningPubMed
Large Vessel Vasculitis: Recent Advances in Pathophysiology and Targeted Therapies.Drugs202642081084PubTator, text miningPubMed

1 to 10 of 3,217

See all 3,217 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/57823

GET https://conductscience.org/api/genes/v1/57823/patents?page=2