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Gene · 5783

PTPN13: protein tyrosine phosphatase non-receptor type 13

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PTPN13: protein tyrosine phosphatase non-receptor type 13. Genes, record 5783. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5783

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Gene

Symbol
PTPN13
HGNC
Name
protein tyrosine phosphatase non-receptor type 13
HGNC
NCBI Gene ID
5783
NCBI Gene
HGNC ID
HGNC:9646
HGNC
Ensembl
ENSG00000163629
NCBI Gene
Aliases
FAP-1, PNP1, PTP-BAS, PTP-BL, PTP1E, PTPL1, PTPLE, hPTP1E
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q12923Tyrosine-protein phosphatase non-receptor type 132,48512Ensembl, GeneID, HGNC

Source UniProt

Patents39

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026049460 A2026-03-181Q12923Espacenet
JP 2026004568 A2026-01-1460068Q12923Espacenet
EP 4650780 A22025-11-1913444Q12923Espacenet
EP 4641201 A22025-10-2915366Q12923Espacenet
JP 2025517969 A2025-06-1215366Q12923Espacenet
JP 2025517970 A2025-06-1213444Q12923Espacenet
US 11827937 B22023-11-2884Q12923Espacenet
US 11446398 B22022-09-2069157Q12923Espacenet
WO 2022176958 A2022-08-259Q12923Espacenet
JP 2022524081 A2022-04-27172128Q12923Espacenet

1 to 10 of 39

See all 39 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants903

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePTPN13 papersNewest fiscal year
P30CA016672Cancer Center Support Grant92025
R01CA069202Structure/Function of Protein Tyrosine Phosphatases72025
P30CA015704Cancer Center Support Grant52025
P30CA046934University of Colorado Cancer Center Support Grant52025
P30CA051008Georgetown University Lombardi Comprehensive Cancer Center Support Grant42025
P30CA076292Moffitt Cancer Center Support Grant42025
P30CA022453CANCER CENTER SUPPORT GRANT32025
R01AG052622Probing organismal proteostasis through the response to intracellular infection32025
R01ES028096Chemical Probes to Study Formaldehyde Biology32025
UL1TR001863Yale Clinical and Translational Science Award32025

1 to 10 of 903Source NIH's project files

See all 903 nih grants

Papers1,279

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
The protein tyrosine phosphatase interactome: beyond catalytic activity.Trends Biochem Sci202642823268PubTator, text miningPubMed
CNTN5 Promotes Invasion and Metastasis in Non-Small Cell Lung Cancer by Regulating YAP1 Nuclear Translocation.J Gene Med202642765163PubTator, text miningPubMed
When membranes fail: FAP-1 and the mega roots of MF.Blood202642720173PubTator, text miningPubMed
PTPN13 Contributes to Ebola Virus-Induced Immune Dysregulation via Dephosphorylation of IRF3 and PI3K-p85.Viruses202642515581PubTator, text miningPubMed
A Quantitative Assessment of Upper Limb Motor Function Across Disease Stages in Hereditary Transthyretin Amyloidosis.J Peripher Nerv Syst202642246655PubTator, text miningPubMed
SHH drives gastric cancer-associated fibroblast activation via ACLY-dependent acetyl-CoA metabolism and histone acetylation.Discov Oncol202642228286PubTator, text miningPubMed
DGAT1 Drives Racially Divergent Fibroblast Activation via ERK1/2-Dependent Tumorigenic Signaling in Prostate Cancer.Cancer Res Commun202642118850PubTator, text miningPubMed
Anti-SIA-cIgG enhances chemotherapy effectiveness through PTPN13-regulated tumor stemness in head and neck squamous cell carcinoma.J Transl Int Med202642046805PubTator, text miningPubMed
PDLIM4 promotes dephosphorylation of STAT transcription factors by recruiting PTP-BL and inhibits Th1, Th2, and Th17 cell differentiation.Int Immunol202642028851PubTator, text miningPubMed
AlloPath: A method for identifying protein allosteric pathway based on transfer entropy and hidden Markov model.Int J Biol Macromol202641985803PubTator, text miningPubMed

1 to 10 of 1,279

See all 1,279 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5783

GET https://conductscience.org/api/genes/v1/5783/patents?page=2