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PTPRC: protein tyrosine phosphatase receptor type C

1 protein, 148 patents, 2 drugs, 3 trials, 30,895 NIH grants and 85,634 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPTPRCHGNC
Nameprotein tyrosine phosphatase receptor type CHGNC
NCBI Gene ID5788NCBI Gene
HGNC IDHGNC:9666HGNC
EnsemblENSG00000081237NCBI Gene
AliasesB220, CD45, CD45R, GP180, IMD105, L-CA, LCA, LY5, T200NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P08575Receptor-type tyrosine-protein phosphatase C1,3066Ensembl, GeneID, HGNCUniProt

Patents 148

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026210451 A12026-10-082P08575Espacenet
EP 4794715 A12026-08-261P08575Espacenet
EP 4771356 A12026-07-0812P08575Espacenet
JP 2026082951 A2026-05-1918P08575Espacenet
EP 4713005 A22026-03-25426P08575Espacenet
JP 2026000906 A2026-01-0631P08575Espacenet
EP 4661970 A12025-12-1762166P08575Espacenet
WO 2025252547 A12025-12-11137P08575Espacenet
EP 4660322 A12025-12-10137P08575Espacenet
JP 2025172753 A2025-11-2636P08575Espacenet

Drugs 2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
AHN-12CHEMBL2109480Leukocyte common antigen binding agentBINDING AGENTChEMBL
BC8 131ICHEMBL2109630Leukocyte common antigen binding agentBINDING AGENTChEMBL

Trials 3

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT01207076AHN-12PHASE1ClinicalTrials.gov
NCT00618696AHN-12PHASE1ClinicalTrials.gov
NCT00003870BC8 131IPHASE2ClinicalTrials.gov

NIH grants 30895

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant5482,025NIH's project files
P30CA016672Cancer Center Support Grant4702,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award1682,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)1572,025NIH's project files
P30AI027763UCSF-Bay Area Center for AIDS Research1372,025NIH's project files
P30CA015704Cancer Center Support Grant1352,025NIH's project files
P30CA016058Cancer Center Support Grant1302,025NIH's project files
P30CA016042Cancer Center Support Grant1202,025NIH's project files
U19AI057229Understanding Influenza and SARS-CoV-2 vaccine responses, in vivo and in vitro1192,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant1162,025NIH's project files

Papers 85634

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818647PubTator, text miningPubMed
42814600PubTator, text miningPubMed
42814317PubTator, text miningPubMed
42812197PubTator, text miningPubMed
42810632PubTator, text miningPubMed
42808463PubTator, text miningPubMed
42807419PubTator, text miningPubMed
42806714PubTator, text miningPubMed
42806169PubTator, text miningPubMed
42805482PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license