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ACTA1: actin alpha 1, skeletal muscle

1 protein, 97 patents, 0 drugs, 0 trials, 9,491 NIH grants and 29,035 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolACTA1HGNC
Nameactin alpha 1, skeletal muscleHGNC
NCBI Gene ID58NCBI Gene
HGNC IDHGNC:129HGNC
EnsemblENSG00000143632NCBI Gene
AliasesACTA, ASMA, CFTD, CFTD1, CFTDM, CMYO2A, CMYO2B, CMYO2C, CMYP2A, CMYP2B, CMYP2C, MPFD, NEM1, NEM2, NEM3, SHPMNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P68133Actin, alpha skeletal muscle3775Ensembl, GeneID, HGNCUniProt

Patents 97

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1436117P68133Espacenet
EP 4641201 A22025-10-298240P68133Espacenet
JP 2025524943 A2025-08-014P68133Espacenet
JP 2025517969 A2025-06-128240P68133Espacenet
JP 2025062604 A2025-04-141498P68133Espacenet
EP 4522755 A22025-03-197P68133Espacenet
EP 4522755 A22025-03-198P68133Espacenet
EP 4522755 A22025-03-199P68133Espacenet
JP 2025013347 A2025-01-24111P68133Espacenet
US 12201675 B22025-01-21111P68133Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 9491

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant672,025NIH's project files
P30CA008748Cancer Center Support Grant422,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award342,025NIH's project files
P30DK084567Mayo Center for Cell Signaling in Gastroenterology332,025NIH's project files
P50AA011999Southern California Research Center for ALPD and Cirrhosis322,025NIH's project files
P30DK034989Yale Liver Center312,025NIH's project files
P30CA006516Dana-Farber/Harvard Cancer Center212,025NIH's project files
P30CA060553The Robert H. Lurie Comprehensive Cancer Center212,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase202,025NIH's project files
P30CA014520UW Comprehensive Cancer Center Support202,025NIH's project files

Papers 29035

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824375PubTator, text miningPubMed
42821141PubTator, text miningPubMed
42818108PubTator, text miningPubMed
42814861PubTator, text miningPubMed
42808027PubTator, text miningPubMed
42805572PubTator, text miningPubMed
42804605PubTator, text miningPubMed
42804009PubTator, text miningPubMed
42801718PubTator, text miningPubMed
42800691PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license