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Gene · 5803

PTPRZ1: protein tyrosine phosphatase receptor type Z1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PTPRZ1: protein tyrosine phosphatase receptor type Z1. Genes, record 5803. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5803

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Gene

Symbol
PTPRZ1
HGNC
Name
protein tyrosine phosphatase receptor type Z1
HGNC
NCBI Gene ID
5803
NCBI Gene
HGNC ID
HGNC:9685
HGNC
Ensembl
ENSG00000106278
NCBI Gene
Aliases
HPTPZ, HPTPzeta, PTP-ZETA, PTP18, PTPRZ, PTPZ, R-PTP-zeta-2, RPTPB, RPTPbeta, phosphacan
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P23471Receptor-type tyrosine-protein phosphatase zeta2,3156Ensembl, GeneID, HGNC

Source UniProt

Patents38

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026110866 A2026-05-289P23471Espacenet
US 12636345 B22026-05-2620P23471Espacenet
JP 2026004568 A2026-01-1460200P23471Espacenet
EP 4650780 A22025-11-1911022P23471Espacenet
EP 4640849 A22025-10-291685P23471Espacenet
EP 4641201 A22025-10-2911444P23471Espacenet
JP 2025529142 A2025-09-043652P23471Espacenet
US 12371689 B22025-07-293652P23471Espacenet
EP 4573109 A22025-06-2510P23471Espacenet
JP 2025519096 A2025-06-241685P23471Espacenet

1 to 10 of 38

See all 38 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants896

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePTPRZ1 papersNewest fiscal year
ZIAHL000659ADP-ribosylation Cycles112025
P30CA021765Cancer Center Support Grant (CCSG)42025
P01CA116087H. pylori-induced Inflammation and Gastric Cancer32025
P30CA008748Cancer Center Support Grant32025
P30CA016058Cancer Center Support Grant32025
P30CA016672Cancer Center Support Grant32025
T32CA009686Training Grant In Tumor Biology32025
I01BX000252Chromatin-based regulation of neural stem cells22025
P01CA163205Circumventing Barriers to Effective Oncolytic Virotherapy of Malignant Gliomas22025
P30AG066509University of Washington Alzheimer's Disease Research Center22025

1 to 10 of 896Source NIH's project files

See all 896 nih grants

Papers1,425

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrated network toxicology and multiomics analyses reveal the mechanisms underlying trimethyltin chloride-induced epilepsy and the ameliorative effects of astaxanthin via NFKB1 and IL6.Ecotoxicol Environ Saf202642810259PubTator, text miningPubMed
Identification of Glioblastoma Cell Surface Proteins and Assessment of Their Expression Across Patient-Derived Stem-Like Cell Cultures.J Proteome Res202642695909PubTator, text miningPubMed
Roles of IL-34 in neurological diseases: neuroprotection, inflammatory regulation, and myeloid plasticity.Front Immunol202642694581PubTator, text miningPubMed
Artificial intelligence-based diagnostic model for identifying PTPRZ1-MET fusion in a clinically defined secondary glioblastoma cohort.Mol Biomed202642547688PubTator, text miningPubMed
A human corticospinal organoid-slice connectoid model informs enhancer strategies for post-injury axon regrowth.Cell Rep202642201810PubTator, text miningPubMed
Cerebrospinal fluid soluble protein tyrosine phosphatase receptor type Z detected with human natural killer-1 antibody as a practical biomarker for glioma diagnosis.Neurooncol Adv202642145875PubTator, text miningPubMed
Nationwide genomic data analysis of central nervous system tumors in Japan based on C-CAT database.Int J Clin Oncol202642089945PubTator, text miningPubMed
The 15-year bibliometric landscape of glioblastoma vaccines: Emergence of combinatorial immunotherapy.Hum Vaccin Immunother202641919662PubTator, text miningPubMed
MET fusions and splicing variants in glioma: a landscape integrating clinical, pathological, and survival features.J Pathol Clin Res202641910014PubTator, text miningPubMed
Precision Immunotherapeutics for Glioblastoma: Current Approaches and Emerging Strategies in 2026.Cells202641892350PubTator, text miningPubMed

1 to 10 of 1,425

See all 1,425 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5803

GET https://conductscience.org/api/genes/v1/5803/patents?page=2