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Gene · 5819

NECTIN2: nectin cell adhesion molecule 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NECTIN2: nectin cell adhesion molecule 2. Genes, record 5819. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5819

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Gene

Symbol
NECTIN2
HGNC
Name
nectin cell adhesion molecule 2
HGNC
NCBI Gene ID
5819
NCBI Gene
HGNC ID
HGNC:9707
HGNC
Ensembl
ENSG00000130202
NCBI Gene
Aliases
CD112, HVEB, Nectin-2, PRR2, PVRL2, PVRR2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q92692Nectin-25387Ensembl, GeneID, HGNC

Source UniProt

Patents155

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4831196 A22026-10-2821Q92692Espacenet
US 12624087 B22026-05-1221Q92692Espacenet
US 12612446 B22026-04-28462Q92692Espacenet
JP 2026049003 A2026-03-178Q92692Espacenet
JP 2026004568 A2026-01-1458296Q92692Espacenet
JP 2026500896 A2026-01-099Q92692Espacenet
EP 4650780 A22025-11-191386Q92692Espacenet
WO 2025235604 A12025-11-139Q92692Espacenet
WO 2025235605 A12025-11-139Q92692Espacenet
JP 2025166053 A2025-11-0521Q92692Espacenet

1 to 10 of 155

See all 155 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,062

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNECTIN2 papersNewest fiscal year
U24AG021886National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)232025
P01AI039671Costimulatory Mechanisms of Autoimmunity122025
P30EY001792P30 Core Grant for Vision Research122025
P30CA008748Cancer Center Support Grant112025
P30AG066468Alzheimer Disease Research Center92025
P30DK063491Diabetes Research Center (DRC)82025
P01CA111412NK cells, their receptors and cancer therapy72025
P30AG062429UCSD Shiley-Marcos Alzheimer's Disease Research Center P3072025
P30AG066444Alzheimer's Disease Research Center72025
P30AG072976Indiana Alzheimer's Disease Research Center72025

1 to 10 of 2,062Source NIH's project files

See all 2,062 nih grants

Papers2,573

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Correction: NECTIN2 depletion impairs migration and invasion in MDA-MB-231 breast cancer cells through LIMK1-associated cytoskeletal remodeling.PLoS One202642789498PubTator, text miningPubMed
Genetic Prioritization of Plasma Proteins Across Dementia Subtypes: A Proteome-Wide Mendelian Randomization and Bayesian Colocalization Analysis.Cell Mol Neurobiol202642782355PubTator, text miningPubMed
Proteome-wide genetic study identified therapeutic targets for early-onset and late-onset Alzheimer's disease.Int J Surg202642682321PubTator, text miningPubMed
NECTIN2 depletion impairs migration and invasion in MDA-MB-231 breast cancer cells through LIMK1-associated cytoskeletal remodeling.PLoS One202642664293PubTator, text miningPubMed
Linoleic acid metabolic reprogramming is linked to immunometabolic remodeling and post-transplant recurrence risk in hepatocellular carcinoma.Front Immunol202642643672PubTator, text miningPubMed
Single-Cell Transcriptome Analysis Reveals IRF1-Driven Epithelial States and Glycosaminoglycan-Glycolysis Coupling in Cisplatin-Resistant HGSOC.Cancer Inform202642605287PubTator, text miningPubMed
Endothelial Cell Proteins as Biomarkers in Susac Syndrome.Ann Clin Transl Neurol202642593056PubTator, text miningPubMed
Metabolism Pathway Blood Proteomic Differences in Lewy Body Dementia Compared to Alzheimer's Disease.Int J Mol Sci202642589529PubTator, text miningPubMed
Spatiotemporal dynamics of the tumor microenvironment in hepatocellular carcinoma during combination immunotherapy.Hepatol Commun202642566272PubTator, text miningPubMed
Single-Cell Transcriptional States of Human Leukocyte Antigen DR Positive CD4 Positive T Cells Linked to Genetic Susceptibility of Gastric Cancer.Immunol Invest202642560142PubTator, text miningPubMed

1 to 10 of 2,573

See all 2,573 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5819

GET https://conductscience.org/api/genes/v1/5819/patents?page=2