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Gene · 583

BBS2: Bardet-Biedl syndrome 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. BBS2: Bardet-Biedl syndrome 2. Genes, record 583. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/583

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Gene

Symbol
BBS2
HGNC
Name
Bardet-Biedl syndrome 2
HGNC
NCBI Gene ID
583
NCBI Gene
HGNC ID
HGNC:967
HGNC
Ensembl
ENSG00000125124
NCBI Gene
Aliases
BBS, RP74
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9BXC9BBSome complex member BBS27210Ensembl, GeneID, HGNC

Source UniProt

Patents20

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515744 A2026-05-19250Q9BXC9Espacenet
JP 2026004568 A2026-01-1438588Q9BXC9Espacenet
EP 4650780 A22025-11-191145Q9BXC9Espacenet
JP 2025517970 A2025-06-121145Q9BXC9Espacenet
JP 2025062604 A2025-04-148253Q9BXC9Espacenet
JP 2025032204 A2025-03-1125093Q9BXC9Espacenet
EP 4461818 A22024-11-1325093Q9BXC9Espacenet
WO 2024214081 A12024-10-17250Q9BXC9Espacenet
JP 2023058610 A2023-04-2525093Q9BXC9Espacenet
US 11446398 B22022-09-208253Q9BXC9Espacenet

1 to 10 of 20

See all 20 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants722

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleBBS2 papersNewest fiscal year
R01GM089933Quality Control of the cilia proteome82025
P30DK084567Mayo Center for Cell Signaling in Gastroenterology62025
R01GM060992Intraflagellar Transport Proteins in Mice52025
I01BX004249Neuronal Mechanisms of Obesity-Induced Hypertension42025
ZIAHD000641Physiology, Psychology, and Genetics of Obesity42025
P30DK026687New York Obesity Research Center32025
P30EY025580Multidisciplinary Investigations in Visual Science32025
R01DK099160Molecular dissection of the ciliary gate32025
R01DK106404Obesity in ciliopathies: How neuronal primary cilia control appetite32025
R01MH101244Functional and population genetic architectures of complex disease32025

1 to 10 of 722Source NIH's project files

See all 722 nih grants

Papers1,279

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A comprehensive overview of genetic mutations in Iranian patients with Bardet-Biedl syndrome.Mol Genet Metab Rep202642774553PubTator, text miningPubMed
Serpin-driven green camouflage and NIR fluorescence in frogs.Sci Adv202642748236PubTator, text miningPubMed
Antigravity Versus Body-Weight-Supported Treadmill Training in Lower-Limb Arthroplasty Rehabilitation: A Randomized Controlled Pilot Trial.J Clin Med202642452380PubTator, text miningPubMed
You can't fight in here! This is BBS!Behav Brain Sci202642379988PubTator, text miningPubMed
Coats-like exudative vasculopathy in a patient with Bardet-Biedl syndrome.Am J Ophthalmol Case Rep202642338809PubTator, text miningPubMed
Distinct correlations between clinical and laboratory-based instrumented balance measures in individuals with multiple sclerosis: a cross-sectional study.Sci Rep202642337379PubTator, text miningPubMed
Clinical heterogeneity associated with Bardet-Biedl syndrome-related genes in presumed non-syndromic inherited retinal disease.Front Cell Dev Biol202642311504PubTator, text miningPubMed
Extracellular stressors change BBSome expression of benign mesothelial and primary pleural mesothelioma cells and affect cell adhesion and migration.Physiol Rep202642304840PubTator, text miningPubMed
An Adaptive Multiparameter Penalty Selection Method for Multiconstraint and Multiblock ADMM.IEEE Open J Signal Process202642021766PubTator, text miningPubMed
A Pilot Study on the Short-Term Effects of an Electric Knee-Ankle-Foot Orthosis on Gait Performance and Physiological Cost Index in Patients With Hemiplegia: Influence of Initial Balance Ability Assessed by the Berg Balance Scale.
Biomed Res Int202641937684PubTator, text miningPubMed

1 to 10 of 1,279

See all 1,279 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/583

GET https://conductscience.org/api/genes/v1/583/patents