Gene · 58476
TP53INP2: tumor protein p53 inducible nuclear protein 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TP53INP2: tumor protein p53 inducible nuclear protein 2. Genes, record 58476. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/58476
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q8IXH6 | Tumor protein p53-inducible nuclear protein 2 | 220 | 7 | Ensembl, GeneID, HGNC |
Source UniProt
Patents39
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 9524 | Q8IXH6 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 9524 | Q8IXH6 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 37474 | Q8IXH6 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 37475 | Q8IXH6 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 37474 | Q8IXH6 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 37475 | Q8IXH6 | Espacenet |
| US 11676731 B2 | 2023-06-13 | 82 | Q8IXH6 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 37474 | Q8IXH6 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 37475 | Q8IXH6 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 94022 | Q8IXH6 | Espacenet |
1 to 10 of 39
See all 39 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,038
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TP53INP2 papers | Newest fiscal year |
|---|---|---|---|
| ZIADA000527 | Medicinal Chemistry of Drugs Acting on Central and Peripheral Opioid Receptors | 6 | 2025 |
| R01DA012864 | Mechanisms and Cellular Function of Opioid Receptor Endocytosis | 5 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 5 | 2025 |
| R01DA008863 | Regulation Of Opioid Receptor Signaling by Endogenous Peptides | 4 | 2025 |
| R28AA012725 | Brain Tissue Resource Center for Alcohol Research | 4 | 2025 |
| ZIAMH002793 | PET Radiopharmaceutical Sciences | 4 | 2025 |
| R01AI164266 | AI-based platform for predicting emerging vaccine-escape variants and designing mutation-proof antibodies | 3 | 2025 |
| R01MH063266 | Roles of nuleus accumbens CREB and Kappa function in depression | 3 | 2025 |
| R01NS038261 | Amygdala pain mechanisms | 3 | 2025 |
| T32DA007027 | Training in the pharmacology of abused drugs | 3 | 2025 |
1 to 10 of 1,038Source NIH's project files
See all 1,038 nih grantsPapers1,281
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Aging-associated loss of CPEB4 impairs mitochondrial adaptation and promotes stress-induced senescence in alveolar type II cells. | Mech Ageing Dev | 2026 | 42764119 | PubTator, text mining | PubMed |
| Initial HIV Therapy for Adults and Treatment-Associated Weight Gain: The Opti-DOR Randomized Clinical Trial. | JAMA | 2026 | 42536019 | PubTator, text mining | PubMed |
| Modular synthesis and bioevaluation of novel fused-β-carbolines as kappa opioid receptor modulators. | Eur J Med Chem | 2026 | 42435554 | PubTator, text mining | PubMed |
| Pharmacological Stratification of Public Bioactivity Databases: A Reusable, OECD-Anchored Curation and Benchmarking Framework Demonstrated for Opioid Receptors. | bioRxiv | 2026 | 42395542 | PubTator, text mining | PubMed |
| Pharmacological Characterization of SLL-022CCP, a Selective κ‑Opioid Receptor Agonist with Potent Antinociceptive Effects and Low Central Side Effects. | ACS Omega | 2026 | 42368158 | PubTator, text mining | PubMed |
| Development and Biological Characterization of Fluorescent Dynorphins for the Visualization of Kappa Opioid Receptors. | J Med Chem | 2026 | 42247579 | PubTator, text mining | PubMed |
| Mechanistic insights into the therapeutic properties of delta opioid receptor. | Sci Adv | 2026 | 41880505 | PubTator, text mining | PubMed |
| To Switch or not to Switch: are there any Antiretroviral Strategies to Attenuate Weight Gain in People with HIV? | Curr HIV/AIDS Rep | 2026 | 41880067 | PubTator, text mining | PubMed |
| Short and Long Non-Coding RNAs in Renal Cell Carcinoma. | Noncoding RNA | 2026 | 41874142 | PubTator, text mining | PubMed |
| Lysosomal down-regulation of the mu opioid receptor is opposed by the Retromer complex. | Sci Adv | 2026 | 41861010 | PubTator, text mining | PubMed |
1 to 10 of 1,281
See all 1,281 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/58476
GET https://conductscience.org/api/genes/v1/58476/patents?page=2