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Gene · 58476

TP53INP2: tumor protein p53 inducible nuclear protein 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TP53INP2: tumor protein p53 inducible nuclear protein 2. Genes, record 58476. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/58476

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Gene

Symbol
TP53INP2
HGNC
Name
tumor protein p53 inducible nuclear protein 2
HGNC
NCBI Gene ID
58476
NCBI Gene
HGNC ID
HGNC:16104
HGNC
Ensembl
ENSG00000078804
NCBI Gene
Aliases
C20orf110, DKFZp434B2411, DKFZp434O0827, DOR, FLJ21759, FLJ23500, PINH, dJ1181N3.1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8IXH6Tumor protein p53-inducible nuclear protein 22207Ensembl, GeneID, HGNC

Source UniProt

Patents39

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-199524Q8IXH6Espacenet
JP 2025517970 A2025-06-129524Q8IXH6Espacenet
JP 2025032204 A2025-03-1137474Q8IXH6Espacenet
JP 2025032204 A2025-03-1137475Q8IXH6Espacenet
EP 4461818 A22024-11-1337474Q8IXH6Espacenet
EP 4461818 A22024-11-1337475Q8IXH6Espacenet
US 11676731 B22023-06-1382Q8IXH6Espacenet
JP 2023058610 A2023-04-2537474Q8IXH6Espacenet
JP 2023058610 A2023-04-2537475Q8IXH6Espacenet
US 11446398 B22022-09-2094022Q8IXH6Espacenet

1 to 10 of 39

See all 39 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,038

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTP53INP2 papersNewest fiscal year
ZIADA000527Medicinal Chemistry of Drugs Acting on Central and Peripheral Opioid Receptors62025
R01DA012864Mechanisms and Cellular Function of Opioid Receptor Endocytosis52025
UL1TR001863Yale Clinical and Translational Science Award52025
R01DA008863Regulation Of Opioid Receptor Signaling by Endogenous Peptides42025
R28AA012725Brain Tissue Resource Center for Alcohol Research42025
ZIAMH002793PET Radiopharmaceutical Sciences42025
R01AI164266AI-based platform for predicting emerging vaccine-escape variants and designing mutation-proof antibodies32025
R01MH063266Roles of nuleus accumbens CREB and Kappa function in depression32025
R01NS038261Amygdala pain mechanisms32025
T32DA007027Training in the pharmacology of abused drugs32025

1 to 10 of 1,038Source NIH's project files

See all 1,038 nih grants

Papers1,281

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Aging-associated loss of CPEB4 impairs mitochondrial adaptation and promotes stress-induced senescence in alveolar type II cells.Mech Ageing Dev202642764119PubTator, text miningPubMed
Initial HIV Therapy for Adults and Treatment-Associated Weight Gain: The Opti-DOR Randomized Clinical Trial.JAMA202642536019PubTator, text miningPubMed
Modular synthesis and bioevaluation of novel fused-β-carbolines as kappa opioid receptor modulators.Eur J Med Chem202642435554PubTator, text miningPubMed
Pharmacological Stratification of Public Bioactivity Databases: A Reusable, OECD-Anchored Curation and Benchmarking Framework Demonstrated for Opioid Receptors.bioRxiv202642395542PubTator, text miningPubMed
Pharmacological Characterization of SLL-022CCP, a Selective κ‑Opioid Receptor Agonist with Potent Antinociceptive Effects and Low Central Side Effects.ACS Omega202642368158PubTator, text miningPubMed
Development and Biological Characterization of Fluorescent Dynorphins for the Visualization of Kappa Opioid Receptors.J Med Chem202642247579PubTator, text miningPubMed
Mechanistic insights into the therapeutic properties of delta opioid receptor.Sci Adv202641880505PubTator, text miningPubMed
To Switch or not to Switch: are there any Antiretroviral Strategies to Attenuate Weight Gain in People with HIV?Curr HIV/AIDS Rep202641880067PubTator, text miningPubMed
Short and Long Non-Coding RNAs in Renal Cell Carcinoma.Noncoding RNA202641874142PubTator, text miningPubMed
Lysosomal down-regulation of the mu opioid receptor is opposed by the Retromer complex.Sci Adv202641861010PubTator, text miningPubMed

1 to 10 of 1,281

See all 1,281 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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