Gene · 58498
MYL7: myosin light chain 7
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. MYL7: myosin light chain 7. Genes, record 58498. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/58498
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q01449 | Myosin regulatory light chain 2, atrial isoform | 175 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents22
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 54749 | Q01449 | Espacenet |
| JP 2024128028 A | 2024-09-20 | 27 | Q01449 | Espacenet |
| US 11760977 B2 | 2023-09-19 | 27 | Q01449 | Espacenet |
| JP 2023123507 A | 2023-09-05 | 305 | Q01449 | Espacenet |
| US 11685901 B2 | 2023-06-27 | 27 | Q01449 | Espacenet |
| JP 2022153580 A | 2022-10-12 | 27 | Q01449 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 54600 | Q01449 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 157571 | Q01449 | Espacenet |
| JP 2022504640 A | 2022-01-13 | 97 | Q01449 | Espacenet |
| EP 3863659 A1 | 2021-08-18 | 27 | Q01449 | Espacenet |
1 to 10 of 22
See all 22 patentsDrugs3
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials45
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT07557498 | MAVACAMTEN | ClinicalTrials.gov | ||
| NCT07541833 | MAVACAMTEN | ClinicalTrials.gov | ||
| NCT07529938 | MAVACAMTEN | ClinicalTrials.gov | ||
| NCT07383025 | MAVACAMTEN | ClinicalTrials.gov | ||
| NCT07361289 | MAVACAMTEN | ClinicalTrials.gov | ||
| NCT07210723 | DANICAMTIV | PHASE2/PHASE3 | ClinicalTrials.gov | |
| NCT07168655 | MAVACAMTEN | ClinicalTrials.gov | ||
| NCT07150299 | MAVACAMTEN | ClinicalTrials.gov | ||
| NCT07120776 | MAVACAMTEN | ClinicalTrials.gov | ||
| NCT07107373 | MAVACAMTEN | ClinicalTrials.gov |
1 to 10 of 45
See all 45 trialsNIH grants855
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MYL7 papers | Newest fiscal year |
|---|---|---|---|
| R01HL076485 | Engineering Vascularized Cardiac Muscle | 7 | 2025 |
| R01HL113006 | Human Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling | 7 | 2025 |
| R01HL128368 | Engineered Stem Cells for Cardiac Repair | 4 | 2025 |
| R01HL151505 | Oxylipin Signaling in Congenital Heart Disease | 4 | 2025 |
| P30CA014520 | UW Comprehensive Cancer Center Support | 3 | 2025 |
| P30DK017047 | Diabetes Research Center | 3 | 2025 |
| R01HL085844 | Functional interactions of cardiac ion channels | 3 | 2025 |
| R01HL130020 | Elucidating Mechanism of Cardiac Fibrosis with Cell Village of Pooled Human iPSCs | 3 | 2025 |
| R01HL131017 | Myocardial remuscularization by cardiac patch delivery of epicardial FSTL1 and CCND2 overexpressing cardiomyocytes | 3 | 2025 |
| R01HL133230 | Mechanisms for cell signaling in the control of cardiomyogenesis | 3 | 2025 |
1 to 10 of 855Source NIH's project files
See all 855 nih grantsPapers788
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| PIP3 antagonist as a molecular regulator in MSC-derived cardiomyocytes: Potential in vitro therapeutic implications for conotruncal heart defects. | J Genet Eng Biotechnol | 2026 | 42749427 | PubTator, text mining | PubMed |
| Human plasma-like medium enhances structural and metabolic maturation of human pluripotent stem cell-derived cardiomyocytes. | Bioeng Transl Med | 2026 | 42272985 | PubTator, text mining | PubMed |
| Coaxially Electrospun Myocardial dECM- Based Nanofibrous Scaffolds Demonstrate Enhanced Cardiomyocyte Biocompatibility. | Adv Healthc Mater | 2026 | 42152235 | PubTator, text mining | PubMed |
| Characterisation of a Missense Variant of the Alström Syndrome Centrosome and Basal Body Associated Protein (ALMS1) Gene Associated with Cardiomyopathy Using Induced Pluripotent Stem Cells. | Genes (Basel) | 2026 | 41751610 | PubTator, text mining | PubMed |
| Pro- and Anti-Inflammatory Cytokines' Implication in Right Heart Disease, Arrhythmogenesis, and Atrial Fibrillation. | Biomolecules | 2026 | 41750286 | PubTator, text mining | PubMed |
| Single-Cell Multi-Omics Profiling of Human Septal Myectomy Tissue: Toward Precision Medicine in Obstructive Hypertrophic Cardiomyopathy. | J Pers Med | 2026 | 41745380 | PubTator, text mining | PubMed |
| Biomimetic electrospun scaffolds for engineered heart tissue: from design parameters to drug testing platforms. | Front Bioeng Biotechnol | 2026 | 41743838 | PubTator, text mining | PubMed |
| TCA cycle intermediates as an adjunct strategy for human iPSC-derived cardiomyocyte maturation. | BBA Adv | 2026 | 41743073 | PubTator, text mining | PubMed |
| Deep immune-phenotyping of HLA-homozygous iPS-cardiomyocytes by spectral flow cytometry. | Front Immunol | 2026 | 41716415 | PubTator, text mining | PubMed |
| PreTSA: computationally efficient modeling of temporal and spatial gene expression patterns. | Genome Biol | 2026 | 41673899 | PubTator, text mining | PubMed |
1 to 10 of 788
See all 788 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/58498
GET https://conductscience.org/api/genes/v1/58498/patents?page=2