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Gene · 58508

KMT2C: lysine methyltransferase 2C

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. KMT2C: lysine methyltransferase 2C. Genes, record 58508. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/58508

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
KMT2C
HGNC
Name
lysine methyltransferase 2C
HGNC
NCBI Gene ID
58508
NCBI Gene
HGNC ID
HGNC:13726
HGNC
Ensembl
ENSG00000055609
NCBI Gene
Aliases
HALR, KIAA1506, KLEFS2, MLL3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8NEZ4Histone-lysine N-methyltransferase 2C4,9119Ensembl, GeneID, HGNC

Source UniProt

Patents27

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1454459Q8NEZ4Espacenet
EP 4650780 A22025-11-192030Q8NEZ4Espacenet
EP 4641201 A22025-10-291594Q8NEZ4Espacenet
JP 2025147176 A2025-10-0615226Q8NEZ4Espacenet
JP 2025517969 A2025-06-121594Q8NEZ4Espacenet
JP 2025517970 A2025-06-122030Q8NEZ4Espacenet
JP 2025028160 A2025-02-2815226Q8NEZ4Espacenet
KR 1020250010750 A2025-01-2115226Q8NEZ4Espacenet
JP 2024109657 A2024-08-1415065Q8NEZ4Espacenet
US 11807852 B22023-11-0747Q8NEZ4Espacenet

1 to 10 of 27

See all 27 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,643

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA008748Cancer Center Support Grant1392025
P30CA016672Cancer Center Support Grant712025
ZIADK075003Enhancer regulation by H3K4 methyltransferase KMT2D/MLL4 and associated factors242025
P30CA006973Regional Oncology Research Center182025
R35CA197569Mutations of Chromatin and its Modifying Machineries in Malignancies172025
P30CA021765Cancer Center Support Grant (CCSG)142025
P30CA016058Cancer Center Support Grant122025
P30CA016086Cancer Center Support Grant122025
P30CA033572Cancer Center Support Grant122025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant122025

1 to 10 of 2,643Source NIH's project files

See all 2,643 nih grants

Papers4,204

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42795000PubTator, text miningPubMed
42784861PubTator, text miningPubMed
42778210PubTator, text miningPubMed
42727675PubTator, text miningPubMed
42727420PubTator, text miningPubMed
42705610PubTator, text miningPubMed
42686832PubTator, text miningPubMed
42626471PubTator, text miningPubMed
42619866PubTator, text miningPubMed
42602752PubTator, text miningPubMed

1 to 10 of 4,204

See all 4,204 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

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