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Gene · 5861

RAB1A: RAB1A, member RAS oncogene family

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RAB1A: RAB1A, member RAS oncogene family. Genes, record 5861. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5861

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Gene

Symbol
RAB1A
HGNC
Name
RAB1A, member RAS oncogene family
HGNC
NCBI Gene ID
5861
NCBI Gene
HGNC ID
HGNC:9758
HGNC
Ensembl
ENSG00000138069
NCBI Gene
Aliases
RAB1, YPT1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P62820Ras-related protein Rab-1A20515Ensembl, GeneID, HGNC

Source UniProt

Patents35

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4801540 A12026-09-097P62820Espacenet
JP 2026506308 A2026-02-243P62820Espacenet
JP 2026004568 A2026-01-1460660P62820Espacenet
EP 4650780 A22025-11-1912154P62820Espacenet
EP 4642905 A12025-11-053P62820Espacenet
EP 4615967 A12025-09-173P62820Espacenet
KR 1020250121452 A2025-08-123P62820Espacenet
EP 4587563 A12025-07-233P62820Espacenet
JP 2025517970 A2025-06-1212154P62820Espacenet
KR 1020250084989 A2025-06-113P62820Espacenet

1 to 10 of 35

See all 35 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,347

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRAB1A papersNewest fiscal year
P30CA008748Cancer Center Support Grant172025
R01GM083144Characterization of mammalian COG complex-interacting Golgi trafficking machinery112025
P30CA016672Cancer Center Support Grant92025
ZIAHD008893Virulence strategies of the respiratory pathogen Legionella pneumophila72025
R35GM136258GTPase Regulation of the Golgi Complex62025
R01GM035370Genetics of secretion in yeast42025
U19AI135990HPMI: Host Pathogen Mapping Initiative42025
P30CA068485Cancer Center Support Grant32025
R01NS092823The role of a-synuclein accumulation in lysosomal hydrolase trafficking and function32025
T32CA009302Leveraging innovative technologies in basic and clinical cancer research32025

1 to 10 of 1,347Source NIH's project files

See all 1,347 nih grants

Papers2,400

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrative Cross-Population Multi-Database Analysis Reveals an Association Between GORASP2 and Autophagy in Glioblastoma.J Pak Med Assoc202642817668PubTator, text miningPubMed
Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf-1/ERK1/2/PINK1 Signaling Axis.Adv Sci (Weinh)202642801566PubTator, text miningPubMed
RAB1 mediates OPTN-dependent mitophagy via ATG9A recruitment.Autophagy202642681746PubTator, text miningPubMed
Crotonylome profiling identifies MLKL crotonylation in lupus nephritis associated with RAB1A-mTOR signalling and autophagy changes in tubular epithelial cells.Lupus Sci Med202642674810PubTator, text miningPubMed
In sample pH measurement by 31P phosphate NMR: application to measure the intrinsic GTPase activity of Rab1a.Eur Biophys J202642347928PubTator, text miningPubMed
Rab1A-Mediated Exosomal Sorting of miR-200c Enhances Breast Cancer Lung Metastasis [Retraction].Breast Cancer (Dove Med Press)202642318227PubTator, text miningPubMed
Tumor regression pattern and distribution of residual tumor cells in potential candidates for local excision of rectal cancer: a prospective cohort study.Tech Coloproctol202642307785PubTator, text miningPubMed
ER-Golgi dysfunction and vesicular transport alterations in rheumatoid arthritis immune cells.Front Immunol202642220485PubTator, text miningPubMed
A novel RAB5 binding site in human VPS34-CII that is likely the primordial site in eukaryotic evolution.Elife202642207670PubTator, text miningPubMed
Renal cell carcinoma with a novel RAB1A::ALK fusion: expanding the molecular spectrum of ALK-rearranged RCC.Virchows Arch202642096086PubTator, text miningPubMed

1 to 10 of 2,400

See all 2,400 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5861

GET https://conductscience.org/api/genes/v1/5861/patents?page=2