Gene · 5867
RAB4A: RAB4A, member RAS oncogene family
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. RAB4A: RAB4A, member RAS oncogene family. Genes, record 5867. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5867
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P20338 | Ras-related protein Rab-4A | 218 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents28
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026094314 A | 2026-06-09 | 65 | P20338 | Espacenet |
| JP 2026021360 A | 2026-02-10 | 156 | P20338 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 60737 | P20338 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 8100 | P20338 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 8241 | P20338 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 8241 | P20338 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 8100 | P20338 | Espacenet |
| JP 2025041709 A | 2025-03-26 | 83 | P20338 | Espacenet |
| JP 2025023947 A | 2025-02-19 | 65 | P20338 | Espacenet |
| JP 2025024092 A | 2025-02-19 | 156 | P20338 | Espacenet |
1 to 10 of 28
See all 28 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,317
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | RAB4A papers | Newest fiscal year |
|---|---|---|---|
| ZIAHD001607 | Protein Trafficking In The Endosomal-Lysosomal System | 9 | 2025 |
| R01DK048370 | Small GTP Binding Proteins in Gastrointestinal Mucosa | 8 | 2025 |
| R01GM083144 | Characterization of mammalian COG complex-interacting Golgi trafficking machinery | 7 | 2025 |
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 6 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 5 | 2025 |
| R01DK064380 | Molecular Mechanisms Regulating Epithelial Cell Apical Polarity and Ciliogenesis | 5 | 2025 |
| P30DK020593 | Vanderbilt Diabetes Research Center | 4 | 2025 |
| P40OD018537 | Bloomington Drosophila Stock Center at Indiana University | 4 | 2025 |
| R01DA012864 | Mechanisms and Cellular Function of Opioid Receptor Endocytosis | 4 | 2025 |
| ZIABC007365 | Regulation of ADP-ribosylation factor | 4 | 2025 |
1 to 10 of 1,317Source NIH's project files
See all 1,317 nih grantsPapers1,548
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Role of Rab4A in the enhancement of cancer cell invasion induced by plasma samples collected during radiotherapy in patients with triple-negative breast cancer. | PLoS One | 2026 | 42743222 | PubTator, text mining | PubMed |
| Engineered exosomes with RNA-motif short hairpin RNA loading and Rab4-boosted production enable controlled ferroptosis in endometrial carcinoma. | Bioeng Transl Med | 2026 | 42666679 | PubTator, text mining | PubMed |
| Lipid-gated vesicular trafficking directs HSPA1A to the plasma membrane through the endo-lysosomal network. | Cell Stress Chaperones | 2026 | 42641754 | PubTator, text mining | PubMed |
| COPI Coatomer Regulates Several Steps of HDL Metabolism. | Arterioscler Thromb Vasc Biol | 2026 | 42592650 | PubTator, text mining | PubMed |
| Membrane lipid composition and rapid endocytic retrieval modulate Wingless secretion. | EMBO J | 2026 | 42547564 | PubTator, text mining | PubMed |
| The N6-methyladenosine reader IGF2BP2 in T-cell lymphoma. | Blood | 2026 | 42166364 | PubTator, text mining | PubMed |
| RAB4A acts as a negative feedback regulator of extracellular vesicle secretion during TGF-β signaling. | FEBS J | 2026 | 41910365 | PubTator, text mining | PubMed |
| The Role of A-Kinase Anchoring Proteins for Inhibitory cAMP Signalling in Platelets. | Cells | 2026 | 41892342 | PubTator, text mining | PubMed |
| Computational Mapping and Targeting of BK Channel Protein-Protein Interactions in Breast Cancer. | J Chem Inf Model | 2026 | 41844387 | PubTator, text mining | PubMed |
| Role of LRRK2 in physiological activities, diseases, and therapy. | Chin Med J (Engl) | 2026 | 41782203 | PubTator, text mining | PubMed |
1 to 10 of 1,548
See all 1,548 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5867
GET https://conductscience.org/api/genes/v1/5867/patents?page=2