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Gene · 5867

RAB4A: RAB4A, member RAS oncogene family

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RAB4A: RAB4A, member RAS oncogene family. Genes, record 5867. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5867

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Gene

Symbol
RAB4A
HGNC
Name
RAB4A, member RAS oncogene family
HGNC
NCBI Gene ID
5867
NCBI Gene
HGNC ID
HGNC:9781
HGNC
Ensembl
ENSG00000168118
NCBI Gene
Aliases
HRES-1, HRES-1/RAB4, HRES1, RAB4
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P20338Ras-related protein Rab-4A2184Ensembl, GeneID, HGNC

Source UniProt

Patents28

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026094314 A2026-06-0965P20338Espacenet
JP 2026021360 A2026-02-10156P20338Espacenet
JP 2026004568 A2026-01-1460737P20338Espacenet
EP 4650780 A22025-11-198100P20338Espacenet
EP 4641201 A22025-10-298241P20338Espacenet
JP 2025517969 A2025-06-128241P20338Espacenet
JP 2025517970 A2025-06-128100P20338Espacenet
JP 2025041709 A2025-03-2683P20338Espacenet
JP 2025023947 A2025-02-1965P20338Espacenet
JP 2025024092 A2025-02-19156P20338Espacenet

1 to 10 of 28

See all 28 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,317

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRAB4A papersNewest fiscal year
ZIAHD001607Protein Trafficking In The Endosomal-Lysosomal System92025
R01DK048370Small GTP Binding Proteins in Gastrointestinal Mucosa82025
R01GM083144Characterization of mammalian COG complex-interacting Golgi trafficking machinery72025
P30DK058404Molecular and Cellular Basis for Digestive Diseases62025
P30CA068485Cancer Center Support Grant52025
R01DK064380Molecular Mechanisms Regulating Epithelial Cell Apical Polarity and Ciliogenesis52025
P30DK020593Vanderbilt Diabetes Research Center42025
P40OD018537Bloomington Drosophila Stock Center at Indiana University42025
R01DA012864Mechanisms and Cellular Function of Opioid Receptor Endocytosis42025
ZIABC007365Regulation of ADP-ribosylation factor42025

1 to 10 of 1,317Source NIH's project files

See all 1,317 nih grants

Papers1,548

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Role of Rab4A in the enhancement of cancer cell invasion induced by plasma samples collected during radiotherapy in patients with triple-negative breast cancer.PLoS One202642743222PubTator, text miningPubMed
Engineered exosomes with RNA-motif short hairpin RNA loading and Rab4-boosted production enable controlled ferroptosis in endometrial carcinoma.Bioeng Transl Med202642666679PubTator, text miningPubMed
Lipid-gated vesicular trafficking directs HSPA1A to the plasma membrane through the endo-lysosomal network.Cell Stress Chaperones202642641754PubTator, text miningPubMed
COPI Coatomer Regulates Several Steps of HDL Metabolism.Arterioscler Thromb Vasc Biol202642592650PubTator, text miningPubMed
Membrane lipid composition and rapid endocytic retrieval modulate Wingless secretion.EMBO J202642547564PubTator, text miningPubMed
The N6-methyladenosine reader IGF2BP2 in T-cell lymphoma.Blood202642166364PubTator, text miningPubMed
RAB4A acts as a negative feedback regulator of extracellular vesicle secretion during TGF-β signaling.FEBS J202641910365PubTator, text miningPubMed
The Role of A-Kinase Anchoring Proteins for Inhibitory cAMP Signalling in Platelets.Cells202641892342PubTator, text miningPubMed
Computational Mapping and Targeting of BK Channel Protein-Protein Interactions in Breast Cancer.J Chem Inf Model202641844387PubTator, text miningPubMed
Role of LRRK2 in physiological activities, diseases, and therapy.Chin Med J (Engl)202641782203PubTator, text miningPubMed

1 to 10 of 1,548

See all 1,548 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

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