Gene · 5874
RAB27B: RAB27B, member RAS oncogene family
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. RAB27B: RAB27B, member RAS oncogene family. Genes, record 5874. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5874
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O00194 | Ras-related protein Rab-27B | 218 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents34
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2025032204 A | 2025-03-11 | 34486 | O00194 | Espacenet |
| EP 4484957 A1 | 2025-01-01 | 72 | O00194 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 34486 | O00194 | Espacenet |
| WO 2023162878 A | 2023-08-31 | 72 | O00194 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 34486 | O00194 | Espacenet |
| US 11446378 B2 | 2022-09-20 | 7 | O00194 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 70660 | O00194 | Espacenet |
| JP 2022532497 A | 2022-07-15 | 39 | O00194 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 173631 | O00194 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 9258 | O00194 | Espacenet |
1 to 10 of 34
See all 34 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants863
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | RAB27B papers | Newest fiscal year |
|---|---|---|---|
| T32ES007326 | Interdisciplinary Research Training Program in Environmental Health and Toxicology | 6 | 2025 |
| T32ES018827 | Research Training in Environmental Toxicology | 6 | 2025 |
| R01NS125016 | Engineering Extracellular Vesicles of Human Brain Organoids for Stroke Therapy | 4 | 2025 |
| ZIAHG000215 | Human Biochemical Genetics | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
| P30CA225520 | Stephenson Cancer Center - Cancer Center Support Grant | 3 | 2025 |
| R01EY011386 | Microtubule-based Transport in Lacrimal Gland Function | 3 | 2025 |
| IK4BX005219 | BLR&D Research Career Development Transition Award Application | 2 | 2025 |
| K12DK100024 | Duke KURe Program | 2 | 2025 |
| P30AG066511 | Goizueta Alzheimer's Disease Research Center | 2 | 2025 |
1 to 10 of 863Source NIH's project files
See all 863 nih grantsPapers1,324
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Identification of a shared blood-brain transcriptomic signature in Parkinson's disease using bioinformatic and network pharmacology approaches. | Neuroscience | 2026 | 42826760 | PubTator, text mining | PubMed |
| Heat-preconditioned MSC-derived exosomal miR‑486‑5p reverses doxorubicin resistance in breast cancer. | Nanomedicine (Lond) | 2026 | 42821374 | PubTator, text mining | PubMed |
| Cross-tissue Mendelian randomization prioritizes RAB27B as a brain-derived candidate protein for postpartum depression. | Eur Arch Psychiatry Clin Neurosci | 2026 | 42584685 | PubTator, text mining | PubMed |
| Cisplatin-Induced Rab27A/B Exosomal PD-L1 Axis Suppresses Antitumor Immunity and Correlates with Poor 5-Year Survival in Lung Squamous Cell Carcinoma and Adenocarcinoma. | Curr Issues Mol Biol | 2026 | 42510937 | PubTator, text mining | PubMed |
| Extracellular vesicle cargo dynamics in the bone marrow microenvironment: from hematopoietic homeostasis to malignant transformation. | Extracell Vesicle | 2026 | 42344609 | PubTator, text mining | PubMed |
| A TRPM4-associated necrotic cell death signature for prognostic stratification in pancreatic cancer. | J Gastrointest Oncol | 2026 | 42169933 | PubTator, text mining | PubMed |
| Rab27: Molecular switch of tumor exosome secretion (Review). | Int J Mol Med | 2026 | 42138205 | PubTator, text mining | PubMed |
| Rab27b: A Modulator of Lysosomal Function and Alpha-Synuclein Clearance in Parkinson's Disease. | J Neurosci | 2026 | 42020315 | PubTator, text mining | PubMed |
| Extracellular Vesicles Associated Metabolites as Intercellular Signalling Mediators in Disease and Therapy. | Metabolites | 2026 | 41893356 | PubTator, text mining | PubMed |
| Linking first-pass reperfusion success to proteomic markers in large and medium vessel ischemic stroke: an exploratory study. | Precis Clin Med | 2026 | 41878235 | PubTator, text mining | PubMed |
1 to 10 of 1,324
See all 1,324 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5874
GET https://conductscience.org/api/genes/v1/5874/patents?page=2