Gene · 5880
RAC2: Rac family small GTPase 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. RAC2: Rac family small GTPase 2. Genes, record 5880. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5880
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P15153 | Ras-related C3 botulinum toxin substrate 2 | 192 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents72
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4801540 A1 | 2026-09-09 | 76 | P15153 | Espacenet |
| WO 2026012976 A1 | 2026-01-15 | 1 | P15153 | Espacenet |
| EP 4661970 A1 | 2025-12-17 | 62167 | P15153 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 1268 | P15153 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 1268 | P15153 | Espacenet |
| JP 2025502257 A | 2025-01-24 | 1 | P15153 | Espacenet |
| WO 2024261302 A1 | 2024-12-26 | 1 | P15153 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 8132 | P15153 | Espacenet |
| EP 4414002 A2 | 2024-08-14 | 1 | P15153 | Espacenet |
| JP 2023522933 A | 2023-06-01 | 1 | P15153 | Espacenet |
1 to 10 of 72
See all 72 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,180
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | RAC2 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 14 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 12 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 8 | 2025 |
| P01CA120964 | Molecular Pathogenesis of the Hamartoma Syndromes | 6 | 2025 |
| ZIAAI000646 | Transgenic Animal Models Of Human Immune Defects | 6 | 2025 |
| ZIAAI000647 | Genes And Gene Products As Immunoadjuvants | 6 | 2025 |
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 4 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 4 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 4 | 2025 |
| P30CA118100 | University of New Mexico Cancer Center Support Grant | 4 | 2025 |
1 to 10 of 2,180Source NIH's project files
See all 2,180 nih grantsPapers3,143
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Human inborn errors of the phagocyte respiratory burst: Chronic granulomatous disease and beyond. | J Hum Immun | 2026 | 42758005 | PubTator, text mining | PubMed |
| Integration of transcriptomics and machine learning to explore inflammatory characteristics and key oxidative stress-related molecules in nasal polyps. | Front Immunol | 2026 | 42718792 | PubTator, text mining | PubMed |
| RAC2 orchestrates immune cell actin remodeling and migration. | Front Immunol | 2026 | 42694400 | PubTator, text mining | PubMed |
| Identification and validation of novel platelet-related genes in ulcerative colitis using bioinformatics and machine learning strategies. | PeerJ | 2026 | 42668808 | PubTator, text mining | PubMed |
| Bioinformatics analysis reveals shared gene signatures and molecular mechanisms between periodontitis and rheumatoid arthritis in the context of aging. | Acta Odontol Scand | 2026 | 42627218 | PubTator, text mining | PubMed |
| Investigating the Cellular Activity and Differential Gene Expression of Human Astrocytes in Interaction with Protein Composite Nanofibers. | Neurochem Res | 2026 | 42599588 | PubTator, text mining | PubMed |
| How Functional Variants Reconfigure the Rac2 Conformational Landscape. | J Phys Chem B | 2026 | 42593131 | PubTator, text mining | PubMed |
| Molecular Pathogenesis and Therapeutic Response of Diffuse Large B Cell Lymphoma Genetic Subtypes. | Annu Rev Cancer Biol | 2026 | 42487683 | PubTator, text mining | PubMed |
| Association Study of Wnt Pathway Genes with Non-syndromic Orofacial Cleft in Han Chinese. | Cleft Palate Craniofac J | 2026 | 42412006 | PubTator, text mining | PubMed |
| CD40LG/CD28-Mediated Rho GTPase Signaling Drives Survival and Chemoresistance in Non-ETP T-ALL. | Int J Mol Sci | 2026 | 42353028 | PubTator, text mining | PubMed |
1 to 10 of 3,143
See all 3,143 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5880
GET https://conductscience.org/api/genes/v1/5880/patents?page=2