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Gene · 5885

RAD21: RAD21 cohesin complex component

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RAD21: RAD21 cohesin complex component. Genes, record 5885. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5885

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Gene

Symbol
RAD21
HGNC
Name
RAD21 cohesin complex component
HGNC
NCBI Gene ID
5885
NCBI Gene
HGNC ID
HGNC:9811
HGNC
Ensembl
ENSG00000164754
NCBI Gene
Aliases
CDLS4, HR21, HRAD21, KIAA0078, MCD1, MGS, NXP1, SCC1, hHR21
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O60216Double-strand-break repair protein rad21 homolog63136Ensembl, GeneID, HGNC

Source UniProt

Patents35

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1460806O60216Espacenet
EP 4650780 A22025-11-193811O60216Espacenet
EP 4641201 A22025-10-293382O60216Espacenet
JP 2025517969 A2025-06-123382O60216Espacenet
JP 2025517970 A2025-06-123811O60216Espacenet
JP 2023182637 A2023-12-2626O60216Espacenet
US 11446398 B22022-09-2071044O60216Espacenet
US 11357853 B22022-06-1428O60216Espacenet
JP 2022524081 A2022-04-27174015O60216Espacenet
JP 2022512673 A2022-02-07266O60216Espacenet

1 to 10 of 35

See all 35 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,912

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRAD21 papersNewest fiscal year
P30CA008748Cancer Center Support Grant472025
P30CA016672Cancer Center Support Grant202025
P30CA010815Consolidated Basic Cancer Research Program172025
P30CA016058Cancer Center Support Grant152025
R01HG003143Structural Annotation of the Human Genome152025
R01CA117830Epigenomic Control of KSHV Latency132025
U10CA180821Alliance for Clinical Trials in Oncology Operations Center - GY11 Funded Extension112025
U10CA180882Alliance Statistics and Data Management Center112025
U24CA196171The Alliance NCTN Biorepository and Biospecimen Resource112025
P30CA021765Cancer Center Support Grant (CCSG)102025

1 to 10 of 2,912Source NIH's project files

See all 2,912 nih grants

Papers3,897

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Human antibody heavy chain variable region exon interacts with the 3' regulatory region to form a stable somatic hypermutation center.Proc Natl Acad Sci U S A202642804635PubTator, text miningPubMed
Cohesin preservation across mitosis contributes to restart transcription via Cdk9-mediated activation of RNAPol2.Mol Cell202642748911PubTator, text miningPubMed
First Cornelia de Lange Syndrome Type 4 Caused by the Gonadal Mosaicism of RAD21 Deletion.Hum Mutat202642719089PubTator, text miningPubMed
A Novel De Novo STAG1 Variant at the RAD21 Binding Interface Is Associated With Hypoglycemia, Recurrent Fever, Immunodeficiency and Features of Classical Cohesinopathies.Clin Genet202642713681PubTator, text miningPubMed
Induced degradation of Ufd1 reveals regulation of cohesin by the VCP/p97Ufd1-Npl4 complex.Life Sci Alliance202642692794PubTator, text miningPubMed
Characterization of Protein Co-Localization and Histone Modifications at Enhancers Anchored in Chromatin Loops.Biology (Basel)202642651636PubTator, text miningPubMed
Diverse Roles of Cohesin in Chromosome Dynamics and Stem Cells.BioTech (Basel)202642645331PubTator, text miningPubMed
Identification of novel UBE2E3::PDE1A and CTC1::MEF2C fusion transcripts in acute myeloid leukemia.Ther Adv Hematol202642621186PubTator, text miningPubMed
Human antibody heavy chain variable region exon interacts with 3' regulatory region to form a stable somatic hypermutation center.bioRxiv202642539176PubTator, text miningPubMed
A 3D genome atlas of human tonsil and the role of loop extrusion in B cell somatic hypermutation.Science202642490500PubTator, text miningPubMed

1 to 10 of 3,897

See all 3,897 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5885

GET https://conductscience.org/api/genes/v1/5885/patents?page=2