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Gene · 5890

RAD51B: RAD51 paralog B

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RAD51B: RAD51 paralog B. Genes, record 5890. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5890

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Gene

Symbol
RAD51B
HGNC
Name
RAD51 paralog B
HGNC
NCBI Gene ID
5890
NCBI Gene
HGNC ID
HGNC:9822
HGNC
Ensembl
ENSG00000182185
NCBI Gene
Aliases
R51H2, RAD51L1, REC2, hREC2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O15315DNA repair protein RAD51 homolog 23845Ensembl, GeneID, HGNC

Source UniProt

Patents20

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1914333O15315Espacenet
JP 2025529142 A2025-09-043667O15315Espacenet
US 12371689 B22025-07-293667O15315Espacenet
JP 2025517970 A2025-06-1214333O15315Espacenet
JP 2024123008 A2024-09-108028O15315Espacenet
US 11597924 B22023-03-07150O15315Espacenet
US 11446398 B22022-09-2071096O15315Espacenet
US 11400116 B22022-08-025699O15315Espacenet
JP 2022524081 A2022-04-27174067O15315Espacenet
US 10501513 B22019-12-108028O15315Espacenet

1 to 10 of 20

See all 20 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,446

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRAD51B papersNewest fiscal year
P30CA008748Cancer Center Support Grant562025
P50CA116201Mayo Clinic Breast Cancer SPORE222025
P30CA016672Cancer Center Support Grant162025
P01CA092584Structural Cell Biology of DNA Repair Machines122025
ZIACP010126Hormone-Related Cancers122025
P30CA016056Roswell Park Cancer Center Support Grant112025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant92025
P30CA006973Regional Oncology Research Center82025
P30CA015704Cancer Center Support Grant72025
P30CA016058Cancer Center Support Grant72025

1 to 10 of 1,446Source NIH's project files

See all 1,446 nih grants

Papers1,861

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A dual gating mechanism controls target-strand cleavage in Cas12j: Implications for engineering efficient nickases.Protein Sci202642742450PubTator, text miningPubMed
Distinct functions of mammalian RAD51 paralogs in genome maintenance.Biochem Soc Trans202642682019PubTator, text miningPubMed
The lncRNA CTD-2566 J3.1 orchestrates oncogenic gene regulation via chromatin interactions in luminal breast cancer.Int J Biol Macromol202642442572PubTator, text miningPubMed
Real-world clinical outcomes, genetic testing patterns, and treatment patterns of patients with metastatic castration-resistant prostate cancer treated with olaparib monotherapy in the United States.Urol Oncol202642431822PubTator, text miningPubMed
New and emerging entities of uterine mesenchymal tumours in the era of molecular testing.Pol J Pathol202642429422PubTator, text miningPubMed
Investigating the shared genetic architecture between selective immunoglobulin A deficiency and autoimmune diseases.Hum Genet202642329450PubTator, text miningPubMed
Integrated transcriptomic and epigenomic profiling reveals conserved molecular subtypes across systemic autoimmune diseases.Ann Rheum Dis202642218077PubTator, text miningPubMed
Uterine Myxoid Inflammatory Myofibroblastic Sarcoma (MIMS) Harboring Pathogenic KRAS Mutations and Expressing ER, PR, and CD10.Int J Gynecol Pathol202642206731PubTator, text miningPubMed
Particulate Hexavalent Chromium Inhibits RAD51 Paralogs Necessary for RAD51 Filament Formation and Stabilization During Homologous Recombination Repair.Occup Health (Auckl)202642169974PubTator, text miningPubMed
Cancer mutations in RAD51 and its paralogues.PLoS One202642133623PubTator, text miningPubMed

1 to 10 of 1,861

See all 1,861 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5890

GET https://conductscience.org/api/genes/v1/5890/patents